Results 11 to 20 of about 21,108 (240)

Dapagliflozin, SGLT2 Inhibitor, Attenuates Renal Ischemia-Reperfusion Injury. [PDF]

PLoS ONE, 2016
Dapagliflozin, a new type of drug used to treat diabetes mellitus (DM), is a sodium/glucose cotransporter 2 (SGLT2) inhibitor. Although some studies showed that SGLT2 inhibition attenuated reactive oxygen generation in diabetic kidney the role of SGLT2 ...
Yoon-Kyung Chang, Hyunsu Choi, Jin Young Jeong, Ki-Ryang Na, Kang Wook Lee, Beom Jin Lim, Dae Eun Choi   +6 more
doaj   +4 more sources

Dapagliflozin versus empagliflozin in patients with chronic kidney disease [PDF]

Frontiers in Pharmacology, 2023
Background and Aim: Dapagliflozin and empagliflozin have demonstrated favorable clinical outcomes among patients with chronic kidney disease (CKD). However, their comparative monetary value for improving outcomes in CKD patients is unestablished.
Hilmi Alnsasra, Hilmi Alnsasra, Gal Tsaban, Gal Tsaban, Adam Solomon, Fouad Khalil, Enis Aboalhasan, Abed N. Azab, Abed N. Azab, Joseph Azuri, Joseph Azuri, Ariel Hammerman, Ronen Arbel   +12 more
doaj   +2 more sources

Antiproteinuric effect of dapagliflozin attenuates tubule-interstitial injury development in subclinical acute kidney injury animal model [PDF]

Frontiers in Pharmacology
IntroductionSubclinical acute kidney injury (subAKI) is characterized by markers of tubular injury without changes in glomerular function, being associated with acute kidney injury and chronic kidney disease.
Rodrigo A. S. Peres, Ana Carolina Pinto-Figueiredo, Douglas E. Teixeira, Douglas E. Teixeira, Rodrigo P. Silva-Aguiar, Sarah A. S. Alves, Giulianne Bastos Serpa, Carlos P. Gomes, Carlos P. Gomes, Wagner Barbosa Dias, Ana Acacia S. Pinheiro, Ana Acacia S. Pinheiro, Ana Acacia S. Pinheiro, Celso Caruso-Neves, Celso Caruso-Neves, Celso Caruso-Neves   +15 more
doaj   +2 more sources

Dapagliflozin

Reactions Weekly
  +17 more sources

Dapagliflozin May Protect Against Doxorubicin-Induced Cardiotoxicity

Anatolian Journal of Cardiology, 2023
Background: Doxorubicin is a widely used agent in the treatment of cancer, but the cardiotoxicity associated with this drug limits its potential for use.
Sebahat Ulusan, Kanat Gülle, Ahmet Peynirci, Murat Sevimli, Adnan Karaibrahimoglu, Mevlüt Serdar Kuyumcu   +5 more
doaj   +1 more source

Therapeutic effect and rebound evaluation of dapagliflozin on glycated hemoglobin (HbA1c) in type 1 diabetes mellitus patients

Frontiers in Pharmacology, 2023
Dapagliflozin has been used to treat patients with type 1 diabetes mellitus; however, the actual drug efficacy of dapagliflozin on glycated hemoglobin (HbA1c) and whether there is a rebound from dapagliflozin efficacy on HbA1c remain unknown. The present
Dong-Dong Wang, Cun Zhang, Ke Hu, Su-Mei He, Ping Zhu, Xiao Chen   +5 more
doaj   +1 more source

Dapagliflozin [PDF]

Hospital Pharmacy, 2014
Each month, subscribers to The Formulary Monograph Service receive 5 to 6 well-documented monographs on drugs that are newly released or are in late phase 3 trials. The monographs are targeted to Pharmacy & Therapeutics Committees. Subscribers also receive monthly 1-page summary monographs on agents that are useful for agendas and pharmacy/nursing ...
Dennis J, Cada, Terri L, Levien, Danial E, Baker   +2 more
openaire   +2 more sources

Dapagliflozin, metformin, monotherapy or both in patients with metabolic syndrome

Scientific Reports, 2021
The present study evaluated the effects of dapagliflozin, a SGLT2 inhibitor, or dapagliflozin plus metformin versus metformin monotherapy in patients with metabolic syndrome.
Lan Cheng, Qianyu Fu, Longhua Zhou, Yuqin Fan, Fenfen Liu, Yuanyuan Fan, Xin Zhang, Weiqing Lin, Xiaohe Wu   +8 more
doaj   +1 more source

The Association between Dapagliflozin Use and the Risk of Post-Contrast Acute Kidney Injury in Patients with Type 2 Diabetes and Chronic Kidney Disease: A Propensity-Matched Analysis

Kidney & Blood Pressure Research, 2023
Introduction: This study aimed to investigate the effect of dapagliflozin in preventing post-contrast acute kidney injury (PC-AKI) in patients with type 2 diabetes (T2DM) and chronic kidney disease (CKD) who underwent an elective coronary procedure ...
Tao Liu, Xinwen Jian, Li Li, Shan Chu, Zeyuan Fan   +4 more
doaj   +1 more source

Dapagliflozin partially restores reproductive function in MC4R KO obese female mice [PDF]

, 2022
Obese women often have certain degree of reproductive dysfunction with infertility. Although the clinical impact of obesity on female infertility has been extensively studied, the effective and targeted treatment is still lacking. Melanocortin-4-receptor
Wang, W, Cowley, M., Wu, M, Roelfsema, F., Cowley, M, Huang, Z, Cui, L., Tan, C.L., Huang, L.L., Geng, F, Wu, M.J., Chen, X, Geng, F., Tan, C, Chen, X.L., Wang, W.H., Cui, L, Roelfsema, F, Huang, L, Chen, C, Huang, Z.X., Chen, C.   +21 more
core   +1 more source