Results 1 to 10 of about 46,179 (165)
Cardiotoxicity of Anthracyclines [PDF]
Frontiers in Cardiovascular Medicine, 2020 Cardiotoxicity is a feared side effect that may limit the clinical use of anthracyclines. It may indeed affect the quality of life and survival of patients with cancer, regardless of oncological prognosis. This paper provides an overview of anthracycline-
Fabiani Iacopo +2 more
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Frontiers in Cardiovascular Medicine, 2022 BackgroundImmune checkpoint inhibitors (ICIs) have achieved acknowledged progress in cancer therapy. However, ICI-associated cardiotoxicity as one of the most severe adverse events is potentially life-threatening, with limited real-world studies ...
Xue Chen +11 more
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Cardiotoxicity with Itraconazole [PDF]
BMJ Case Reports, 2017 Itraconazole is a commonly used antifungal drug. In addition to commonly described adverse effects, there have been few reports of heart failure with its use. We present two cases that developed acute systolic heart failure with Itraconazole use. A man in his early 30s was admitted with worsening leg swelling and dyspnoea on exertion.
Vishesh, Paul, Harsh, Rawal
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Toll-like Receptor 4 Inflammatory Perspective on Doxorubicin-Induced Cardiotoxicity
Molecules, 2023 Doxorubicin (Dox) is one of the most frequently used chemotherapeutic drugs in a variety of cancers, but Dox-induced cardiotoxicity diminishes its therapeutic efficacy.
Natticha Sumneang +2 more
doaj +1 more source
Cardiotoxicity of fluoroquinolones [PDF]
Journal of Antimicrobial Chemotherapy, 2002 Currently marketed fluoroquinolones enjoy an admirable safety profile that is not matched by any other antibiotic group. The widespread use of fluoroquinolones in the elderly, who are susceptible to cardiac arrhythmias because of underlying heart diseases, metabolic derangement and use of anti-arrhythmic agents and other medications that prolong the QT
Ethan, Rubinstein, John, Camm
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Paracetamol cardiotoxicity [PDF]
Postgraduate Medical Journal, 1993 Summary A 29 year old man with a significant paracetamol overdose was found to have an abnormal electrocardiograph which, in the absence of hepatic encephalopathy, was considered due to a direct cardiotoxic effect of the drug. A functional coronary insufficiency resulting from inhibition of endothelium-derived relaxing factor secondary ...
A, Armour, S D, Slater
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Cardiovascular complications in patients with cancer: focus on anthracycline-induced cardiotoxicity
Кардиоваскулярная терапия и профилактика, 2021 The article describes prevalence and risk factors of cardiovascular in patients with cancer. The problems of anthracycline-induced cardiotoxicity, the deleterious effects of doxorubicin on the heart, as well as the cardioprotective effects of beta ...
I. T. Murkamilov +5 more
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eJHaem, 2020 We investigated the incidence of cardiotoxicity, its risk factors, and the clinical course of cardiac function in patients with malignant lymphoma (ML) who received a cyclophosphamide, doxorubicin, vincristine, and prednisolone (CHOP) regimen.
Takafumi Nakayama +19 more
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Tripartite motif 25 ameliorates doxorubicin-induced cardiotoxicity by degrading p85α
Cell Death and Disease, 2022 Doxorubicin (DOX)-based chemotherapy is widely used to treat malignant tumors; however, the cardiotoxicity induced by DOX restricts its clinical usage. A therapeutic dose of DOX can activate ubiquitin-proteasome system. However, whether and how ubiquitin-
Yihui Shen +10 more
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Journal of Clinical and Translational Science, 2021 IMPACT: Advanced cardiac magnetic resonance imaging techniques can help to protect cancer patients from cardiotoxicity from immunotherapy with a more sensitive assessment of cardiac function with strain imaging for detection of abnormal cardiac function ...
Jason Cuomo +8 more
doaj +1 more source