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Cardiomyocyte Regeneration [PDF]
Cells, 2013 The heart was initially believed to be a terminally differentiated organ; once the cardiomyocytes died, no recovery could be made to replace the dead cells. However, around a decade ago, the concept of cardiac stem cells (CSCs) in adult hearts was proposed. CSCs differentiate into cardiomyocytes, keeping the heart functioning.
Toshio Nakanishi, Nanako Kawaguchi
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Frontiers in Cell and Developmental Biology, 2020 To identify and analyze the live proliferating cardiomyocytes is crucial for deciphering the mechanisms controlling endogenous cardiac regeneration. Traditional methods confuse cell division with multinucleation in postnatal cardiomyocytes.
Wenbin Fu +22 more
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The Formin FHOD1 in Cardiomyocytes [PDF]
The Anatomical Record, 2014 ABSTRACTMembers of the formin family are known to be involved in the regulation of the actin cytoskeleton. We have recently identified a muscle specific splice variant of the formin FHOD3 and demonstrated its role in the maintenance of the contractile filaments of cardiomyocytes.
Dwyer, J +4 more
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Cells, 2023 (1) Pulmonary hypertension (PH)-associated right ventricular (RV) failure is linked to a reduction in pulmonary vasodilators. Treprostinil has shown effectiveness in PAH patients with cardiac decompensation, hinting at potential cardiac benefits.
Aleksandra Judina +8 more
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Dyadic Plasticity in Cardiomyocytes [PDF]
Frontiers in Physiology, 2018 Contraction of cardiomyocytes is dependent on sub-cellular structures called dyads, where invaginations of the surface membrane (t-tubules) form functional junctions with the sarcoplasmic reticulum (SR). Within each dyad, Ca2+ entry through t-tubular L-type Ca2+ channels (LTCCs) elicits Ca2+ release from closely apposed Ryanodine Receptors (RyRs) in ...
Peter P. Jones +5 more
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No functional TRPA1 in cardiomyocytes [PDF]
Acta Physiologica, 2021 AbstractAimThere is mounting evidence that TRPA1 has a role in cardiac physiology and pathophysiology. We aim to clarify the site of TRPA1 expression in the heart and in particular whether the channel is expressed in cardiomyocytes.MethodsDue to the high calcium conductance of TRPA1, and marginal calcium changes being detectable, microfluorimetry in ...
Clara Hoebart +9 more
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AUTOHEMOCHEMOTHERAPY IN CANCER OF THE MAMMARY GLANDS IN CATS
Ветеринарная патология, 2020 This article discusses one of the options for reducing the post-therapeutic complications caused by antineoplastic drugs used in the treatment of mammary glands cancer in cats. There are various ways to reduce the toxicity of chemotherapy drugs.
V. V. Sukhomlinov
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Requirements for human cardiomyocytes [PDF]
Cell Proliferation, 2021 Abstract‘Requirements for human cardiomyocytes', jointly drafted and agreed upon by experts from the Chinese Society for Stem Cell Research, is the first guideline for human cardiomyocytes in China. This standard specifies the technical requirements, test methods, test regulations, instructions for use, labelling requirements, packing requirements ...
Miao Yu +26 more
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Cardiomyocyte Regeneration [PDF]
Circulation, 2017 Consensus ...
Eschenhagen, T +18 more
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Cell Transplantation, 2008 Various cytokines produced by bone marrow cells can protect adult cardiomyocytes against apoptosis. Thus, we investigated the feasibility of implanting adult cardiomyocytes in combination with bone marrow cells for myocardial repair.
Tao-Sheng Li M.D., Ph.D. +6 more
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