Results 31 to 40 of about 234,827 (207)

Communication Between Cardiomyocytes and Fibroblasts During Cardiac Ischemia/Reperfusion and Remodeling: Roles of TGF-β, CTGF, the Renin Angiotensin Axis, and Non-coding RNA Molecules

open access: yesFrontiers in Physiology, 2021
Communication between cells is a foundational concept for understanding the physiology and pathology of biological systems. Paracrine/autocrine signaling, direct cell-to-cell interplay, and extracellular matrix interactions are three types of cell ...
Raúl Flores-Vergara   +10 more
doaj   +1 more source

Electrical coupling between ventricular myocytes and myofibroblasts in the infarcted mouse heart [PDF]

open access: yes, 2017
Aims: Recent studies have demonstrated electrotonic coupling between scar tissue and the surrounding myocardium in cryoinjured hearts. However, the electrical dynamics occurring at the myocyte-nonmyocyte interface in the fibrotic heart remain ...
Conway, Simon J.   +6 more
core   +1 more source

Estrogen Protects the Female Heart from Ischemia/Reperfusion Injury through Manganese Superoxide Dismutase Phosphorylation by Mitochondrial p38β at Threonine 79 and Serine 106. [PDF]

open access: yes, 2016
A collective body of evidence indicates that estrogen protects the heart from myocardial ischemia/reperfusion (I/R) injury, but the underlying mechanism remains incompletely understood. We have previously delineated a novel mechanism of how 17β-estradiol
Kim, Jin Kyung, Liu, Han, Luo, Tao
core   +1 more source

Hopx and the Cardiomyocyte Parentage [PDF]

open access: yesMolecular Therapy, 2015
The dissection of steps that pattern primitive mesoderm toward the cardiovascular lineages is important to our current understanding of cardiovascular development and can instruct regenerative approaches to heart repair.1 Primitive precursors that can adopt a cardiovascular fate, but also a subset of other mesoderm, are marked by the transcription ...
Schneider, MD, Baker, AH, Riley, P
openaire   +3 more sources

Atrial fibrillation and electrophysiology in transgenic mice with cardiac-restricted overexpression of FKBP12 [PDF]

open access: yes, 2019
Cardiomyocyte-restricted overexpression of FK506-binding protein 12 transgenic (αMyHC-FKBP12) mice develop spontaneous atrial fibrillation (AF). The aim of the present study is to explore the mechanisms underlying the occurrence of AF in αMyHC-FKBP12 ...
Ai, Tomohiko   +14 more
core   +1 more source

Transplantation of cryopreserved cardiomyocytes [PDF]

open access: yesThe Journal of Thoracic and Cardiovascular Surgery, 2001
The present study examined the survival and rate of contraction of (1) cardiomyocytes cultured from cryopreserved fetal rat myocardium and (2) cryopreserved cultured cardiomyocytes. In addition, the effects of transplantation of cryopreserved fetal cardiomyocytes were evaluated.Segments of fetal rat myocardial tissue (0.2, 2.0, and 6.0 mm(3) mince size)
Yokomuro, Hiroki   +5 more
openaire   +2 more sources

IMMUNOHISTOCHEMICAL EVALUATION OF VASOENDOTHELIAL GROWTH FACTOR RECEPTOR-2 (VEGFR2) EXPRESSION IN RAT CARDIOMYOCYTES UNDER DOXORUBICIN AND BETULONIC ACID AMIDE ADMINISTRATION

open access: yesСибирский научный медицинский журнал, 2019
The aim of the study is to perform an immunohistochemical analysis of the expression of the vascular endothelial growth factor receptor 2 (VEGFR2) in the myocardium of Wistar rats in doxorubicin-induced cardiomyopathy and the administration of betulonic ...
L. L. Elena   +3 more
doaj   +1 more source

Ginsenoside Re Treatment Attenuates Myocardial Hypoxia/Reoxygenation Injury by Inhibiting HIF-1α Ubiquitination

open access: yesFrontiers in Pharmacology, 2020
Previous studies have shown an attenuating effect of ginsenoside Re on myocardial injury induced by hypoxia/reoxygenation (H/R). However, the underlying mechanism remains unclear.
Huiyuan Sun   +19 more
doaj   +1 more source

How to alleviate cardiac injury from electric shocks at the cellular level

open access: yesFrontiers in Cardiovascular Medicine, 2022
Electric shocks, the only effective therapy for ventricular fibrillation, also electroporate cardiac cells and contribute to the high-mortality post-cardiac arrest syndrome.
Pamela W. Sowa   +9 more
doaj   +1 more source

Mechanisms of exercise-induced improvements in the contractile apparatus of the mammalian myocardium [PDF]

open access: yes, 2010
One of the main outcomes of aerobic endurance exercise training is the improved maximal oxygen uptake, and this is pivotal to the improved work capacity that follows the exercise training.
Adams   +98 more
core   +1 more source

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