Results 21 to 30 of about 180,189 (308)

Fucoxanthin protects neonatal rat cardiomyocytes and attenuates high glucose-mediated oxidative stress via the AMPK pathway

, 2020
Introduction Diabetic cardiomyopathy (DC) is associated with impaired diastolic function. Hyperglycemia-mediated oxidative stress and apoptosis are the major factors responsible for DC.
Chunxia Lei, Fengyue Li
core   +1 more source

Differentiation of cardiomyocyte.

Folia Pharmacologica Japonica, 2000
In the recent decade, remarkable progress has been made in the field of cardiac development through the use of molecular, biological and genetic techniques. Several genes that regulate this process have been cloned, and their functions have been analyzed in vivo and in vitro.
OKA, Toru, KOMURO, Issei
openaire   +3 more sources

Transcriptomic analyses of murine ventricular cardiomyocytes [PDF]

, 2018
Mice are used universally as model organisms for studying heart physiology, and a plethora of genetically modified mouse models exist to study cardiac disease.
Wyler, Kurt, Chevalier, Morgan, Vermij, Sarah H., Keller, Irene, Gillet, Ludovic, Abriel, Hugues   +5 more
core   +2 more sources

Intracellular zinc modulates cardiac ryanodine receptor-mediated calcium release [PDF]

, 2015
This work was supported by University of St. Andrews, Tenovus Scotland Grant T14/35 (to S. J. P.), British Heart Foundation Grant FS/14/69/31001 (to S. J.
Woodier, Jason, J. Woodier (7634894), S. J. Pitt (7634900), A. J. Stewart (7634897), Pitt, Samantha Jane, Stewart, Alan J., Rainbow, Richard D., Richard D. Rainbow (7619696)   +7 more
core   +1 more source

Cardiomyocyte Regeneration [PDF]

Circulation, 2017
Consensus ...
Eschenhagen, T, Bolli, R, Braun, T, Field, LJ, Fleischmann, BK, Frisén, J, Giacca, M, Hare, JM, Houser, S, Lee, RT, Marbán, E, Martin, JF, Molkentin, JD, Murry, CE, Riley, PR, Ruiz-Lozano, P, Sadek, HA, Sussman, MA, Hill, JA   +18 more
openaire   +6 more sources

HL-1 cells express an inwardly rectifying K+ current activated via muscarinic receptors comparable to that in mouse atrial myocytes [PDF]

, 2010
An inwardly rectifying K^+ current is present in atrial cardiac myocytes that is activated by acetylcholine (I_{KACh}). Physiologically, activation of the current in the SA node is important in slowing the heart rate with increased parasympathetic tone ...
Muriel Nobles, Sonia Sebastian, Tinker, A., Andrew Tinker, Nobles, M., Sebastian, S., Nobles, Muriel   +6 more
core   +1 more source

Human induced pluripotent stem cell-derived cardiomyocytes as an electrophysiological model: Opportunities and challenges-The Hamburg perspective. [PDF]

, 2023
Models based on human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) are proposed in almost any field of physiology and pharmacology. The development of human induced pluripotent stem cell-derived cardiomyocytes is expected to become a ...
Koivumäki, Jussi, Koivumäki, Jussi T., Schulz, Carl, Koivumäki, Jussi T, Ismaili, Djemail, Hansen, Arne, Mika, Delphine, Eschenhagen, Thomas, Christ, Torsten, Horváth, András   +9 more
core   +2 more sources

IMMUNOHISTOCHEMICAL EVALUATION OF VASOENDOTHELIAL GROWTH FACTOR RECEPTOR-2 (VEGFR2) EXPRESSION IN RAT CARDIOMYOCYTES UNDER DOXORUBICIN AND BETULONIC ACID AMIDE ADMINISTRATION

Сибирский научный медицинский журнал, 2019
The aim of the study is to perform an immunohistochemical analysis of the expression of the vascular endothelial growth factor receptor 2 (VEGFR2) in the myocardium of Wistar rats in doxorubicin-induced cardiomyopathy and the administration of betulonic ...
L. L. Elena, M. M. Mzhelskaya, E. V. Koldysheva, M. G. Klinnikova   +3 more
doaj   +1 more source

Ginsenoside Re Treatment Attenuates Myocardial Hypoxia/Reoxygenation Injury by Inhibiting HIF-1α Ubiquitination

Frontiers in Pharmacology, 2020
Previous studies have shown an attenuating effect of ginsenoside Re on myocardial injury induced by hypoxia/reoxygenation (H/R). However, the underlying mechanism remains unclear.
Huiyuan Sun, Huiyuan Sun, Huiyuan Sun, Shukuan Ling, Dingsheng Zhao, Jianwei Li, Yang Li, Hua Qu, Ruikai Du, Ying Zhang, Feng Xu, Yuheng Li, Caizhi Liu, Guohui Zhong, Shuai Liang, Zizhong Liu, Xingcheng Gao, Xiaoyan Jin, Yingxian Li, Dazhuo Shi   +19 more
doaj   +1 more source

How to alleviate cardiac injury from electric shocks at the cellular level

Frontiers in Cardiovascular Medicine, 2022
Electric shocks, the only effective therapy for ventricular fibrillation, also electroporate cardiac cells and contribute to the high-mortality post-cardiac arrest syndrome.
Pamela W. Sowa, Pamela W. Sowa, Pamela W. Sowa, Aleksander S. Kiełbik, Aleksander S. Kiełbik, Andrei G. Pakhomov, Emily Gudvangen, Uma Mangalanathan, Volker Adams, Olga N. Pakhomova   +9 more
doaj   +1 more source