Results 11 to 20 of about 133,857 (267)

FBPase is in the nuclei of cardiomyocytes [PDF]

FEBS Letters, 2003
Intracellular localization of FBPase in the cardiac muscle of the pig was studied by immunohistochemistry. In contrast to data from skeletal muscle [Gizak, A., Rakus, D. and Dzugaj, A. (2003) Histol. Histopathol. 18, 135–142], in cardiomyocytes FBPase was present not only in the cytoplasm, but surprisingly, also in the nucleus.
Gizak, A, Dzugaj, A
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Nucleus Mechanosensing in Cardiomyocytes

International Journal of Molecular Sciences, 2023
Cardiac muscle contraction is distinct from the contraction of other muscle types. The heart continuously undergoes contraction–relaxation cycles throughout an animal’s lifespan. It must respond to constantly varying physical and energetic burdens over the short term on a beat-to-beat basis and relies on different mechanisms over the long term.
Isabella Leite Coscarella, Maicon Landim-Vieira, Hosna Rastegarpouyani, Prescott Bryant Chase, Jerome Irianto, Jose Renato Pinto   +5 more
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Differentiation of cardiomyocyte.

Folia Pharmacologica Japonica, 2000
In the recent decade, remarkable progress has been made in the field of cardiac development through the use of molecular, biological and genetic techniques. Several genes that regulate this process have been cloned, and their functions have been analyzed in vivo and in vitro.
OKA, Toru, KOMURO, Issei
openaire   +3 more sources

Sulfur Dioxide Derivative Prevents the Prolongation of Action Potential During the Isoproterenol-Induced Hypertrophy of Rat Cardiomyocytes

Anais da Academia Brasileira de Ciências, 2021
Exogenous SO2 is toxic especially to the pulmonary and cardiovascular system, similar to nitric-oxide, carbon-monoxide, and hydrogen-sulfide. Endogenous SO2 is produced in many cell types.
UĞUR DALAMAN, HASAN ÖZDOĞAN, AHMED K. SIRCAN, SEVGI A. ŞENGÜL, NAZMI YARAŞ   +4 more
doaj   +1 more source

Role of Mitophagy in Coronary Heart Disease: Targeting the Mitochondrial Dysfunction and Inflammatory Regulation

Frontiers in Cardiovascular Medicine, 2022
Coronary heart disease (CHD) is one of the main causes of death worldwide. In the past few decades, several in-depth research on the pathological mechanisms and effective treatment methods for CHD have been conducted.
Mingxuan Liu, Ying Wu
doaj   +1 more source

Impact of Opuntia ficus-indica Fruit Extracts on Toxicity Induced by Doxorubicin in Cardiomyocytes [PDF]

Research Journal of Pharmacognosy
Background and objectives: Doxorubicin is an antineoplastic agent whose administration may cause cardiotoxicity. Opuntia ficus-indica is a widely consumed cactus species with nutritional and antioxidant value.
Leila Safaeian*, Masoud Sadeghi-Dinani, Arezou Ramezani, Mansooreh Asghari-Varzaneh   +3 more
doaj   +1 more source

The Regulator of G Protein Signaling Homologous Domain of G Protein-Coupled Receptor Kinase 2 Mediates Short-Term Desensitization of β3-Adrenergic Receptor

Frontiers in Pharmacology, 2020
G protein coupled receptor (GPCR) kinases (GRKs) are key regulators of GPCR signaling. Canonical mechanism of GPCR desensitization involves receptor phosphorylation by GRKs followed by arrestin recruitment and uncoupling from heterotrimeric G protein ...
Emiliana Echeverría, Emiliana Echeverría, Maia Cabrera, Maia Cabrera, Valeria Burghi, Valeria Burghi, Máximo Sosa, Máximo Sosa, Sonia Ripoll, Sonia Ripoll, Agustín Yaneff, Agustín Yaneff, Federico Monczor, Federico Monczor, Carlos Davio, Carlos Davio, Carina Shayo, Natalia Fernández, Natalia Fernández   +18 more
doaj   +1 more source

The β2-Subunit of Voltage-Gated Calcium Channels Regulates Cardiomyocyte Hypertrophy

Frontiers in Cardiovascular Medicine, 2021
L-type voltage-gated calcium channels (LTCCs) regulate crucial physiological processes in the heart. They are composed of the Cavα1 pore-forming subunit and the accessory subunits Cavβ, Cavα2δ, and Cavγ. Cavβ is a cytosolic protein that regulates channel
Simone Pickel, Yiliam Cruz-Garcia, Sandra Bandleon, Katalin Barkovits, Katalin Barkovits, Cornelia Heindl, Katharina Völker, Marco Abeßer, Kathy Pfeiffer, Kathy Pfeiffer, Alice Schaaf, Katrin Marcus, Katrin Marcus, Petra Eder-Negrin, Michaela Kuhn, Michaela Kuhn, Erick Miranda-Laferte, Erick Miranda-Laferte   +17 more
doaj   +1 more source

Communication Between Cardiomyocytes and Fibroblasts During Cardiac Ischemia/Reperfusion and Remodeling: Roles of TGF-β, CTGF, the Renin Angiotensin Axis, and Non-coding RNA Molecules

Frontiers in Physiology, 2021
Communication between cells is a foundational concept for understanding the physiology and pathology of biological systems. Paracrine/autocrine signaling, direct cell-to-cell interplay, and extracellular matrix interactions are three types of cell ...
Raúl Flores-Vergara, Raúl Flores-Vergara, Ivonne Olmedo, Ivonne Olmedo, Pablo Aránguiz, Jaime Andrés Riquelme, Jaime Andrés Riquelme, Raúl Vivar, Zully Pedrozo, Zully Pedrozo, Zully Pedrozo   +10 more
doaj   +1 more source

Hopx and the Cardiomyocyte Parentage [PDF]

Molecular Therapy, 2015
The dissection of steps that pattern primitive mesoderm toward the cardiovascular lineages is important to our current understanding of cardiovascular development and can instruct regenerative approaches to heart repair.1 Primitive precursors that can adopt a cardiovascular fate, but also a subset of other mesoderm, are marked by the transcription ...
Schneider, MD, Baker, AH, Riley, P
openaire   +3 more sources