Results 11 to 20 of about 180,189 (308)

The Formin FHOD1 in Cardiomyocytes [PDF]

The Anatomical Record, 2014
ABSTRACTMembers of the formin family are known to be involved in the regulation of the actin cytoskeleton. We have recently identified a muscle specific splice variant of the formin FHOD3 and demonstrated its role in the maintenance of the contractile filaments of cardiomyocytes.
Dwyer, J, Pluess, M, Iskratsch, T, dos Remedios, CG, Ehler, E   +4 more
openaire   +5 more sources

The role of bone marrow derived cells in cardiac repair [PDF]

, 2012
PhDCurrent pharmacological therapies fail to address the final end-point of cardiac ischaemia — the death and dysfunction of cardiomyocytes. Advances in stem cell biology have provided hope, for the first time, of addressing this underlying pathology.
Lovell, Matthew J.
core   +4 more sources

Cardiomyocyte Regeneration [PDF]

Cells, 2013
The heart was initially believed to be a terminally differentiated organ; once the cardiomyocytes died, no recovery could be made to replace the dead cells. However, around a decade ago, the concept of cardiac stem cells (CSCs) in adult hearts was proposed. CSCs differentiate into cardiomyocytes, keeping the heart functioning.
Toshio Nakanishi, Nanako Kawaguchi
openaire   +3 more sources

Wang et al. Supplementary Files_DMD iPSC-cardiomyocytes

, 2023
The DMD iPSCs were differentiated into beating cardiomyocytes following the protocol for cardiac lineage differentiation based on a stepwise supplementation of iPSC medium with specific small molecules (Campostrini et al. 2021 Nat. Protoc., 16, 2213-2256.
Manuel Goncalves (17675433)
core   +1 more source

Requirements for human cardiomyocytes [PDF]

Cell Proliferation, 2021
Abstract‘Requirements for human cardiomyocytes', jointly drafted and agreed upon by experts from the Chinese Society for Stem Cell Research, is the first guideline for human cardiomyocytes in China. This standard specifies the technical requirements, test methods, test regulations, instructions for use, labelling requirements, packing requirements ...
Miao Yu, Wei Lei, Jiani Cao, Lei Wang, Aijin Ma, Zhen‐Ao Zhao, Huang‐Tian Yang, Zhenya Shen, Feng Lan, Feng Cao, Ping Liang, Xuetao Pei, Andy Peng Xiang, Junying Yu, Yu Zhang, Yong Zhang, Qiyuan Li, Jiaxi Zhou, Jun Wei, Yaojin Peng, Huanxin Zhu, Lingmin Liang, Nan Cao, Boqiang Fu, Jie Hao, Tongbiao Zhao, Shijun Hu   +26 more
openaire   +2 more sources

Dyadic Plasticity in Cardiomyocytes [PDF]

Frontiers in Physiology, 2018
Contraction of cardiomyocytes is dependent on sub-cellular structures called dyads, where invaginations of the surface membrane (t-tubules) form functional junctions with the sarcoplasmic reticulum (SR). Within each dyad, Ca2+ entry through t-tubular L-type Ca2+ channels (LTCCs) elicits Ca2+ release from closely apposed Ryanodine Receptors (RyRs) in ...
Peter P. Jones, Peter P. Jones, Niall MacQuaide, Niall MacQuaide, William E. Louch, William E. Louch   +5 more
openaire   +6 more sources

Reactivation of the mitosis-promoting factor in postmitotic cardiomyocytes [PDF]

, 2003
Cardiomyocytes cease to divide shortly after birth and an irreversible cell cycle arrest is evident accompanied by the downregulation of cyclin-dependent kinase activities.
Datwyler, D. A., Weikert, C., Wightman, L., Magyar, J. P., Hans M. Eppenberger, Wagner, E., Eppenberger, H. M., Josef P. Magyar, Lionel Wightman, Daniel A. Dätwyler, Ernst Wagner, Christian Weikert   +11 more
core   +1 more source

Mena/VASP and αII-Spectrin complexes regulate cytoplasmic actin networks in cardiomyocytes and protect from conduction abnormalities and dilated cardiomyopathy [PDF]

, 2013
BACKGROUND: In the heart, cytoplasmic actin networks are thought to have important roles in mechanical support, myofibrillogenesis, and ion channel function.
Benz, PM, Frantz, Stefan, Merkel, CJ, Offner, Kristin, Fleming, Ingrid, Feller, Stephan M., Renné, T, Gambaryan, Stepan, Unger, A, Linke, Wolfgang A., Fischer, T, Merkel, Carla J., Bayer, B, Schuh, K, Benz, Peter M., Wagner, Helga, Ullrich, Melanie, Linke, WA, Bayer, Barbara, Ullrich, M, Offner, K, Renné, Thomas, Abeßer, M, Ursitti, Jeanine A., Frantz, S, Adham, Ibrahim M., Unger, Andreas, Adham, IM, Feller, SM, Fischer, Tobias, Wagner, H, Abeßer, Marco, Schuh, Kai, Gambaryan, S, Fleming, I, Ursitti, JA   +35 more
core   +1 more source

Exercise training corrects control of spontaneous calcium waves in hearts from myocardial infarction heart failure rats [PDF]

, 2011
Impaired cardiac control of intracellular diastolic Ca²⁺ gives rise to arrhythmias. Whereas exercise training corrects abnormal cyclic Ca²⁺ handling in heart failure, the effect on diastolic Ca<sup>2 ...
Kemi, Ole J., Wisloff, Ulrik, Morten A. Hoydal, MacQuaide, Niall, Godfrey L. Smith, Hoydal, Morten A., Smith, Godfrey L., Ellingsen, Oyvind, Oyvind Ellingsen, Smith, Godfrey L, Niall MacQuaide, Ole J. Kemi, Ulrik Wisloff   +12 more
core   +1 more source

Slow Turning Lateral Vessel Bioreactor Improves Embryoid Body Formation and Cardiogenic Differentiation of Mouse Embryonic Stem Cells. [PDF]

, 2013
Embryonic stem cells (ESCs) have the ability to form aggregates, which are called embryoid bodies (EBs). EBs mimic early embryonic development and are commonly produced for cardiomyogenesis.
Tharasanit, T., Biology of Reproductive Cells, Pirity, M., Rungarunlert, Sasitorn, Klincumhom, Nuttha, Rungarunlert, S., Dinnyés, András, Tharasanit, Theerawat, Dep Gezondheidszorg Landbouwhuisdieren, Klincumhom, N., Techakumphu, M., Pirity, Melinda, Dinnyes, A.   +12 more
core   +2 more sources