Results 1 to 10 of about 13,026,798 (304)

A Simple and Low-Cost, but Naturalistic Method for Introducing Students to Action Potentials

open access: yesBrazilian Archives of Biology and Technology, 2021
Current trends in science education recommend the complementary use of virtual and hands-on methods of teaching. In neurobiology, for instance, there is a plethora of virtual laboratories and simulators that can be readily combined with traditional ...
Orlando Jorquera, Edgar Harry Vogel
doaj   +1 more source

Sensitivity Analysis of Ion Channel Conductance on Myocardial Electromechanical Delay: Computational Study

open access: yesFrontiers in Physiology, 2021
It is well known that cardiac electromechanical delay (EMD) can cause dyssynchronous heart failure (DHF), a prominent cardiovascular disease (CVD). This work computationally assesses the conductance variation of every ion channel on the cardiac cell to ...
Ali Ikhsanul Qauli   +2 more
doaj   +1 more source

Resilience of compound action potential peaks to high‐frequency firing in the mouse optic nerve

open access: yesPhysiological Reports, 2023
Action potential conduction in axons triggers trans‐membrane ion movements, where Na+ enters and K+ leaves axons, leading to disruptions in resting trans‐membrane ion gradients that must be restored for optimal axon conduction, an energy dependent ...
Amy J. Hopper   +2 more
doaj   +1 more source

Differences in Intersubject Early Readiness Potentials Between Voluntary and Instructed Actions

open access: yesFrontiers in Psychology, 2020
Readiness potential (RP) is a slow negative electroencephalogram (EEG) potential prior to voluntary action and was first described by Kornhuber and Deecke (1965).
Lipeng Zhang   +11 more
doaj   +1 more source

In vivo Overexpression of Electrogenic Sodium/Bicarbonate Cotransporter (NBCe1) by AAV9 Modifies the Cardiac Action Potential and the QT Interval in Mice

open access: yesFrontiers in Cardiovascular Medicine, 2022
Cardiac cells depend on specific sarcolemmal ion transporters to assure the correct intracellular pH regulation. The sodium/bicarbonate cotransporter (NBC) is one of the major alkalinizing mechanisms.
Romina A. Di Mattía   +7 more
doaj   +1 more source

On mathematical modeling of the propagation of a wave ensemble within an individual axon

open access: yesFrontiers in Cellular Neuroscience, 2023
The long history of studying the propagation of an action potential has revealed that an electrical signal is accompanied by mechanical and thermal effects. All these effects together generate an ensemble of waves. The consistent models of such a complex
Tanel Peets   +3 more
doaj   +1 more source

Distinct dendritic Ca2+ spike forms produce opposing input-output transformations in rat CA3 pyramidal cells

open access: yeseLife, 2021
Proper integration of different inputs targeting the dendritic tree of CA3 pyramidal cells (CA3PCs) is critical for associative learning and recall.
Ádám Magó   +3 more
doaj   +1 more source

A Mathematical Model of the Mouse Atrial Myocyte With Inter-Atrial Electrophysiological Heterogeneity

open access: yesFrontiers in Physiology, 2020
Biophysically detailed mathematical models of cardiac electrophysiology provide an alternative to experimental approaches for investigating possible ionic mechanisms underlying the genesis of electrical action potentials and their propagation through the
Henggui Zhang   +8 more
doaj   +1 more source

ALTERNATIVE TO Q WAVE DIAGNOSIS USING CARDIAC ACTION POTENTIAL PROPAGATION TIME MEASUREMENT

open access: yesРоссийский кардиологический журнал, 2016
The diagnosis of myocardial infarction is done by ECG through the observation of Q waves in one or more leads. The paper describes the relationship between Q waves and the propagation time of the Cardiac Action potential and a technique by which this ...
S. Ananthi, V. Vignesh, K. Padmanabhan
doaj   +1 more source

Kv3.3 subunits control presynaptic action potential waveform and neurotransmitter release at a central excitatory synapse

open access: yeseLife, 2022
Kv3 potassium currents mediate rapid repolarisation of action potentials (APs), supporting fast spikes and high repetition rates. Of the four Kv3 gene family members, Kv3.1 and Kv3.3 are highly expressed in the auditory brainstem and we exploited this to
Amy Richardson   +9 more
doaj   +1 more source

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