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Emerging Roles of the Membrane Potential: Action Beyond the Action Potential [PDF]
Whilst the phenomenon of an electrical resting membrane potential (RMP) is a central tenet of biology, it is nearly always discussed as a phenomenon that facilitates the propagation of action potentials in excitable tissue, muscle, and nerve. However, as
Lina Abdul Kadir +2 more
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Artificial Action Potential and Ionic Power Device Inspired by Ion Channels and Excitable Cell
In vivo, the membrane potential of the excitable cell working by ion gradients plays a significant role in bioelectricity generation and nervous system operation.
Jung‐Soo Kim +4 more
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Cardiac calcium alternans is defined as beat-to-beat alternations of Ca transient (CaT) amplitude and has been linked to cardiac arrhythmia, including atrial fibrillation.
Kathrin Banach, Lothar A. Blatter
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Mechanisms of Synaptic Vesicle Exo- and Endocytosis
Within 1 millisecond of action potential arrival at presynaptic terminals voltage–gated Ca2+ channels open. The Ca2+ channels are linked to synaptic vesicles which are tethered by active zone proteins. Ca2+ entrance into the active zone triggers: (1) the
Sumiko Mochida
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Human iPSC-Derived Cortical Neurons Display Homeostatic Plasticity
Maintaining the excitability of neurons and circuits is fundamental for healthy brain functions. The global compensatory increase in excitatory synaptic strength, in response to decreased activity, is one of the main homeostatic mechanisms responsible ...
Federica Cordella +9 more
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Essential oil composition and antinociceptive activity of Thymus capitatus
Context: The essential oil (EO) from Thymus capitatus Hoff. et Link. (Lamiaceae) has been traditionally used for its medicinal properties, such as anti-inflammatory, analgesic, antioxidant and antimicrobial properties.
Juan Carlos Ramos Gonçalves +7 more
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Background and aims Although studies on the relation between arrhythmias and the action potential duration (APD) have been carried out, most of them are based only on electrophysiological factors of the heart and lack experiments that consider cardiac ...
Da Un Jeong, Ki Moo Lim
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Dynamics of action potential firing in electrically connected striatal fast-spiking interneurons
Fast-spiking interneurons (FSIs) play a central role in organizing the output of striatal neural circuits, yet functional interactions between these cells are still largely unknown.
Giovanni eRusso +3 more
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Neurocomputational mechanisms underlying perception and sentience in the neocortex
The basis for computation in the brain is the quantum threshold of “soliton,” which accompanies the ion changes of the action potential, and the refractory membrane at convergences.
Andrew S. Johnson +2 more
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Electrical restitution (ER) is a determinant of cardiac repolarization stability and can be measured as steady action potential (AP) duration (APD) at different pacing rates—the so-called dynamic restitution (ERdyn) curve—or as APD changes after pre- or ...
Massimiliano Zaniboni
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