Results 31 to 40 of about 46,179 (165)
Archives of Medical ScienceIntroduction Trastuzumab and anthracyclines are mainstays of chemotherapy in breast cancer and lymphoma patients but may cause significant cardiotoxicity, which may result in alterations to chemotherapy dose, schedule, or agent.
Mallorie L. Huff +10 more
doaj +1 more source
The puzzling clinical presentation of fluoropyrimidines cardiotoxicity
Frontiers in Cardiovascular Medicine, 2022 The cardiotoxicity of fluoropyrimidines (FP) [5-Fluorouracil and Capecitabine] is often reported as acute cardiac ischemia with rest typical angina, signs of ischemia at electrocardiogram (ECG), and ventricular kinetics abnormalities.
Linda Cucciniello +5 more
doaj +1 more source
Utility of myocardial work by echocardiography in the early diagnosis of cardiotoxicity [PDF]
Exploration of CardiologyAim: Evaluate the role of myocardial work by echocardiography and determine its utility as an early diagnosis of cardiotoxicity. Methods: Single-center included 180 patients over 18 years old undergoing chemotherapy, the definition of cardiotoxicity for ...
Denise Cortes-Pérez +4 more
doaj +1 more source
Acute and early-onset cardiotoxicity in children and adolescents with cancer: a systematic review
BMC Cancer, 2023 Background Cardiotoxicity is among the most important adverse effects of childhood cancer treatment. Anthracyclines, mitoxantrone and radiotherapy involving the heart are its main causes. Subclinical cardiac dysfunction may over time progress to clinical
Theodorus W. Kouwenberg +9 more
doaj +1 more source
Role of acetylation in doxorubicin-induced cardiotoxicity
Redox Biology, 2021 As a potent chemotherapeutic agent, doxorubicin (DOX) is widely used for the treatment of a variety of cancers However, its clinical utility is limited by dose-dependent cardiotoxicity, and pathogenesis has traditionally been attributed to the formation ...
Daisong Li +9 more
doaj +1 more source
Risk factors for fluorouracil-induced cardiotoxicity in patients with gastrointestinal tumor
Frontiers in Cardiovascular MedicineObjectiveTo explore the risk factors for cardiotoxicity in patients with gastrointestinal (GI) tumors treated with fluorouracil drugs.MethodsThis study included patients with GI tumors who received fluorouracil at our hospital between January 2018 and ...
Yuting Wu +4 more
doaj +1 more source
Cardiotoxicity and Cancer Therapy [PDF]
Angiology, 2013 A fundamental concept of treatment is to do no harm. However, with cancer treatment this is not always possible. Chemotherapy is associated with cardiovascular (CV) complications.1,2 This risk is even greater in the elderly patients and patients with established CV disease.
Vasiliadis, I +2 more
openaire +3 more sources
A Review on Effects of Cardiotoxic Drugs in Animal Models
JLUMHS, 2021 The major types of Cardiotoxicity in humans are mainly drug-induced, trauma, and stress-induced. Animal models for drug-induced Cardiotoxicity are generated by using various categories of drugs including anticancer, antiretroviral and antidiabetic, etc ...
Dr. Bader Alsuwayt
doaj +1 more source
Understanding Anthracycline Cardiotoxicity From Mitochondrial Aspect
Frontiers in Pharmacology, 2022 Anthracyclines, such as doxorubicin, represent one group of chemotherapy drugs with the most cardiotoxicity. Despite that anthracyclines are capable of treating assorted solid tumors and hematological malignancies, the side effect of inducing cardiac ...
Junqi Huang +5 more
doaj +1 more source
Anthracycline Cardiotoxicity in Children [PDF]
New England Journal of Medicine, 2004 More than 70 percent of children who are treated for childhood cancer can be cured. For long-term survivors, possible late effects of treatment and their consequences for the quality of life are a major concern. Cardiotoxic effects of anthracyclines are among the most frequent and serious adverse effects of the treatment of childhood cancer ...
Kremer, L.C.M., Caron, H.N.
openaire +5 more sources