Results 51 to 60 of about 46,179 (165)

NLRP3 inflammasome as a therapeutic target in doxorubicin-induced cardiotoxicity: role of phytochemicals

Frontiers in Pharmacology
Doxorubicin (DOX) has received widespread attention as a broad-spectrum antitumor drug. However, it has been a recognized challenge that long-term DOX injections can lead to severe cardiotoxicity.
Xiao-Peng Zhao, Lian Duan, Lian Duan, Qian-Ru Zhao, Xing Lv, Nai-Yuan Tian, Sheng-Lei Yang, Kun Dong   +7 more
doaj   +1 more source

Digitalis cardiotoxicity

Journal of the American College of Cardiology, 1985
Clinical manifestations of digitalis toxicity were clearly described by Withering in 1785. One hundred years later, certain digitalis-induced arrhythmias were inscribed on the smoked drum, and shortly thereafter with the introduction of the electrocardiograph, manifestations of digitalis toxicity as recognized today were recorded in animals and human ...
Fisch, Charles, Knoebel, Suzanne B.
openaire   +2 more sources

Evaluation of miR-146a as a potential biomarker for diagnosis of cardiotoxicity induced by chemotherapy in patients with breast cancer

Journal of Research in Medical Sciences
Background: Cardiotoxicity from chemotherapy may result in cardiomyopathy and heart failure. Clinicians can use the evaluation of cardiotoxicity-specific biomarkers, such as microRNA, as a tool for the early detection of cardiotoxicity.
Nasrin Zare, Nasim Dana, Azam Mosayebi, Golnaz Vaseghi, Shaghayegh Haghjooy Javanmard   +4 more
doaj   +1 more source

Modified Routine Cardiac Imaging Surveillance of Adult Cancer Patients and Survivors During the COVID-19 Pandemic

JACC. CardioOncology, 2020
Oscar Calvillo-Argüelles, MD, Husam Abdel-Qadir, MD, PhD, Bonnie Ky, MD, MSCE, Jennifer E. Liu, MD, Juan C. Lopez-Mattei, MD, Eitan Amir, MD, PhD, Paaladinesh Thavendiranathan, MD, SM   +6 more
doaj   +1 more source

Macrotroponin interference and association with cardiotoxicity in patients receiving cardiotoxic breast cancer therapy: a pilot study

Cardio-Oncology
Background Cancer therapy-related cardiac dysfunction (CTRCD) is an important adverse effect in patients receiving potential cardiotoxic cancer therapies.
Andrea Soosaipillai, Inbar Nardi-Agmon, Davor Brinc, Anselmo Fabros, Peter A. Kavsak, Paaladinesh Thavendiranathan, Ashley Di Meo   +6 more
doaj   +1 more source

Managing 5FU Cardiotoxicity in Colorectal Cancer Treatment

Cancer Management and Research, 2022
Matthew Anaka, Omar Abdel-Rahman Department of Oncology, Cross Cancer Institute, University of Alberta, Edmonton, AB, CanadaCorrespondence: Omar Abdel-RahmanDepartment of Oncology, Cross Cancer Institute, University of Alberta, 11560 University Avenue ...
Anaka M, Abdel-Rahman O
doaj  

Deubiquitinase MYSM1 promotes doxorubicin-induced cardiotoxicity by mediating TRIM21-ferroptosis axis in cardiomyocytes

Cell Communication and Signaling
Anthracycline antitumor drug doxorubicin (DOX) induces severe cardiotoxicity. Deubiquitinating enzymes (DUBs) are crucial for protein stability and function and play a significant role in cardiac pathophysiology.
Xiaowen Shi, Jianjiang Xu, Xin Zhong, Yuanyuan Qian, Liming Lin, Zimin Fang, Bozhi Ye, Yiting Lyu, Ran Zhang, Zhanxiong Zheng, Jibo Han   +10 more
doaj   +1 more source

Heart rate variability-based prediction of early cardiotoxicity in breast-cancer patients treated with anthracyclines and trastuzumab

Cardio-Oncology
Background Cardiotoxicity is a recognized complication in breast cancer (BC) patients undergoing chemotherapy with anthracyclines with or without trastuzumab.
Santiago Luna-Alcala, Adrián Espejel-Guzmán, Claudia Lerma, Paula Leon, Enrique C. Guerra, Jose Rodrigo Espinosa Fernández, Pavel Martinez-Dominguez, Javier Serrano-Roman, Aldo Cabello-Ganem, Alexis D. Aparicio-Ortiz, Candace Keirns, Abel Lerma, Maria Jose Santa Ana-Bayona, Nilda Espinola-Zavaleta   +13 more
doaj   +1 more source

An intelligent biosensing platform using phase space reconstruction‐assisted convolutional neural network for drug‐induced cardiotoxicity assessment

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Drug‐induced cardiotoxicity often leads to patient deaths and drug recalls. Interdigitated electrode (IDE)‐based cellular impedance detection instrument has been integrated with intelligent algorithms to screen cardiotoxicity based on cardiomyocytes ...
Wenjian Yang, Xinyu Guo, Ruochen Wu, Yue Wu, Minzhi Fan, Bihu Lv, Diming Zhang, Zhijing Zhu   +7 more
doaj   +1 more source

REPLY: Reframing Mechanistic and Clinical Paradigms of Osimertinib-Associated Cardiotoxicity. [PDF]

JACC CardioOncol
Tanaka Y, Tatebe Y, Hamano H, Zamami Y.
europepmc   +1 more source