Results 1 to 10 of about 34,211 (250)

Updates in Anthracycline-Mediated Cardiotoxicity

Frontiers in Pharmacology, 2018
Cardiotoxicity is one of the main adverse effects of chemotheraphy, affecting the completion of cancer therapies and the short- and long-term quality of life.
Canan G. Nebigil, Laurent Désaubry
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Altered Peripheral Blood Gene Expression in Childhood Cancer Survivors With Anthracycline‐Induced Cardiomyopathy – A COG‐ALTE03N1 Report

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Anthracycline‐induced cardiomyopathy is a leading cause of premature death in childhood cancer survivors, presenting a need to understand the underlying pathogenesis.
Purnima Singh, Disheet A. Shah, Mariam Jouni, Romina B. Cejas, David K. Crossman, Tarek Magdy, Shaowei Qiu, Xuexia Wang, Liting Zhou, Noha Sharafeldin, Lindsey Hageman, Donald E. McKenna, Saro H. Armenian, Frank M. Balis, Douglas S. Hawkins, Frank G. Keller, Melissa M. Hudson, Joseph P. Neglia, A Kim Ritchey, Jill P. Ginsberg, Wendy Landier, Ravi Bhatia, Paul W. Burridge, Smita Bhatia   +23 more
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Relationship between Chemotherapy and Atrial Fibrillation: Clinical Case

Рациональная фармакотерапия в кардиологии, 2021
The aim of this article is to represent the characterization of the clinical case of chemotherapy-related atrial fibrillation (AF) development in the young woman, elaborated as a result of multiple neoadjuvant and adjuvant modes of the intake of ...
A. A. Avagimyan, L. H. Mkrtchyan, A. A. Gevorkyan, N. B. Kononchuk, L. V. Kakturskiy, Z. T. Djndoyan   +5 more
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Redefining the role of anthracyclines in early breast cancer treatment

Academia Oncology
Anthracyclines have long been a cornerstone of early breast cancer treatment, contributing to significant reductions in recurrence and improvements in survival.
Guilherme Nader-Marta, Martine Piccart
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Novel Polyhedral Silsesquioxanes [POSS(OH)₃₂] as Anthracycline Nanocarriers—Potential Anticancer Prodrugs

Molecules, 2020
Anthracyclines belong to the anticancer drugs that are widely used in chemotherapy. However, due to their systemic toxicity they also exert dangerous side effects associated mainly with cardiovascular risks.
Kinga Piorecka, Jan Kurjata, Wlodzimierz A. Stanczyk   +2 more
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Cardiotoxicity of venetoclax in patients with acute myeloid leukemia: comparison with anthracyclines

Cardio-Oncology
Venetoclax is a promising drug for patients with acute myeloid leukemia (AML) ineligible for anthracycline-based treatments. In rats, venetoclax is reported to cause myocardial injury.
Takeshi Onoue, Andrew H. Matthews, Azin Vakilpour, Yu Kang, Bénédicte Lefebvre, Amanda M. Smith, Shannon R. McCurdy, Michael G. Fradley, Joseph Carver, Jesse Chittams, Marielle Scherrer-Crosbie   +10 more
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Potent immune-dependent anticancer effects of the non-cardiotoxic anthracycline aclarubicin

OncoImmunology
Aclarubicin (also called aclacinomycin A) is an antineoplastic from the anthracycline class that is used in China and Japan but not in Europe nor in the USA.
Giulia Cerrato, Allan Sauvat, Mahmoud Abdellatif, Guido Kroemer   +3 more
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Extrato hidroalcoolico da casca do pequi (Caryocar brasiliense) em ratos submetidos à aplicação de doxorrubicina Hydro alcoholic extract of pequi peel (Caryocar brasiliense) in rats submitted to the application of doxorubicin

Ciência Rural, 2013
O objetivo deste estudo foi avaliar o efeito antioxidante do extrato hidroalcoolico da casca do pequi (EHCP) em ratos após a administração de doxorrubicina (DOX).
Léa Resende Moura, Aparecida Conceição Martins, Liliam Aparecida da Rocha Vaz, Stiwens Roberto Trevisan Orpinelli, Thiago Lopes da Silva, Mariana Batista Rodrigues Faleiro, Suzana da Costa Santos, Veridiana Maria Briagnezi Dignani de Moura   +7 more
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Pediatric Cardio-Oncology: Screening, Risk Stratification, and Prevention of Cardiotoxicity Associated with Anthracyclines

Children
Anthracyclines have significantly improved the survival of children with malignant tumors, but the associated cardiotoxicity, an effect now under the purview of pediatric cardio-oncology, due to its cumulative and irreversible effects on the heart ...
Xiaomeng Liu, Shuping Ge, Aijun Zhang
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Efficacy of Neurohormonal Therapies in Preventing Cardiotoxicity in Patients With Cancer Undergoing Chemotherapy

JACC. CardioOncology, 2019
Objectives: This study sought to assess the effects of neurohormonal therapies in preventing cardiotoxicity in patients receiving chemotherapy.
Muthiah Vaduganathan, MD, MPH, Sameer A. Hirji, MD, MPH, Arman Qamar, MD, Navkaranbir Bajaj, MD, MPH, Ankur Gupta, MD, PhD, Vlad G. Zaha, MD, Alvin Chandra, MD, Mark Haykowsky, PhD, Bonnie Ky, MD, MSCE, Javid Moslehi, MD, Anju Nohria, MD, Javed Butler, MD, MPH, MBA, Ambarish Pandey, MD, MSCS   +12 more
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