Results 1 to 10 of about 47,221 (287)
WikiJournal of Medicine, 2018 Anthracyclines are a clinically important class of antineoplastic agents used to treat a wide variety of solid and blood cancers. The first described anthracycline, daunorubicin, was first isolated from a strain of Streptomyces peucetius in the early ...
Alison Cheong +2 more
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Molecules, 2021 The aim of this study was to evaluate the bioremoval of anthracycline antibiotics (daunomycin-DNR, doxorubicin–DOX, and mitoxantrone-MTX) by immobilized mycelium of B. adusta CCBAS 930.
Kamila Rybczyńska-Tkaczyk
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Cardiac magnetic resonance assessment of right ventricular remodeling after anthracycline therapy
Scientific Reports, 2021 There are limited data on the effects of anthracyclines on right ventricular (RV) structure, function, and tissue characteristics. The goal of this study was to investigate the effects of anthracyclines on the RV using cardiac magnetic resonance (CMR ...
Thiago Ferreira de Souza +13 more
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The Role of miRNAs in the Resistance of Anthracyclines in Breast Cancer: A Systematic Review
Frontiers in Oncology, 2022 Breast cancer has been reported as the most common cancer in women globally, with 2.26 million new cases in 2020. While anthracyclines are the first-line drug for breast cancer, they cause a variety of adverse reactions and drug resistance, especially ...
Zihan Si +10 more
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DNA damage independent inhibition of NF-κB transcription by anthracyclines
eLife, 2022 Anthracyclines are among the most used and effective anticancer drugs. Their activity has been attributed to DNA double-strand breaks resulting from topoisomerase II poisoning and to eviction of histones from select sites in the genome.
Angelo Ferreira Chora +25 more
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Cardiotoxicity of Anthracyclines
Frontiers in Cardiovascular Medicine, 2020 Cardiotoxicity is a feared side effect that may limit the clinical use of anthracyclines. It may indeed affect the quality of life and survival of patients with cancer, regardless of oncological prognosis. This paper provides an overview of anthracycline-
Daniela Cardinale +2 more
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Right ventricular dysfunction during chemotherapy in patients with breast cancer
Кардиоваскулярная терапия и профилактика, 2022 Aim. To assess the right ventricle (RV) during chemotherapy (CT) in patients with breast cancer (BC).Material and methods. The study included 40 women aged 35-72 years with BC who underwent anthracycline chemotherapy. The main group (n=40) included women
A. N. Sumin +4 more
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Ranolazine Attenuates Trastuzumab-Induced Heart Dysfunction by Modulating ROS Production [PDF]
, 2018 The ErbB2 blocker trastuzumab improves survival in oncologic patients, but can cause cardiotoxicity. The late Na+ current inhibitor ranolazine has been shown to counter experimental HF, including doxorubicin cardiotoxicity (a condition characterized by ...
Carlo G. Tocchetti +16 more
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Experimental Hematology & Oncology, 2012 Background Liposomal formulations of anthracyclines appear to have favorable toxicity profile when compared with conventional anthracyclines in elderly, high risk cardiac patients and patients with prior use of anthracyclines.
Rafiyath Shamudheen M +5 more
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Prophylactic use of carvedilol to prevent ventricular dysfunction in patients with cancer treated with doxorubicin [PDF]
, 2018 Objective: Deterioration in ventricular function is often observed in patients treated with anthracyclines for cancer. There is a paucity of evidence on interventions that might provide cardio-protection.
Abrar, Mohammed Burhan +8 more
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