Results 41 to 50 of about 27,000 (252)
Relationship between Chemotherapy and Atrial Fibrillation: Clinical Case
Рациональная фармакотерапия в кардиологии, 2021 The aim of this article is to represent the characterization of the clinical case of chemotherapy-related atrial fibrillation (AF) development in the young woman, elaborated as a result of multiple neoadjuvant and adjuvant modes of the intake of ...
A. A. Avagimyan +5 more
doaj +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
Сhanges in Blood Pressure in Patients with Breast Cancer during Polychemotherapy with Anthracyclines
Львівський клінічний вісникIntroduction. Elevated blood pressure (BP) during treatment with anthracyclines, which include doxorubicin and epirubicin, may be a factor in polychemotherapy (PCT)-related cardiotoxicity, which necessitates monitoring and adjustment of BP in these ...
Світлана Бусел +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Antitumour Drug Induced Cardiovascular Toxicity and Current Tumour Treatment Methods
Креативная хирургия и онкология, 2020 Currently the oncological mortality takes the second place globally, the leading cause being cardiovascular diseases. The statistics of malignant neoplasms is rather negative all over the world.
K. S. Gumerova +2 more
doaj +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Predictive and Prognostic Relevance of ABC Transporters for Resistance to Anthracycline Derivatives
BiomoleculesAnthracyclines have been clinically well established in cancer chemotherapy for decades. The main limitations of this drug class are the development of resistance and severe side effects.
Rümeysa Yücer +5 more
doaj +1 more source
State of Vegetative Homeostasis in Children with Anthracycline-Induced Cardiomyopathy
Zdorovʹe Rebenka, 2014 The paper presents the results of investigation of the autonomic nervous system in children with acute lymphoblastic leukemia, in whom as a result of protocol chemotherapy with anthracycline antibiotics application, toxic anthracycline-induced ...
T.V. Shatynska +2 more
doaj +1 more source