Results 21 to 30 of about 34,211 (250)
Cardiac magnetic resonance assessment of right ventricular remodeling after anthracycline therapy
Scientific Reports, 2021 There are limited data on the effects of anthracyclines on right ventricular (RV) structure, function, and tissue characteristics. The goal of this study was to investigate the effects of anthracyclines on the RV using cardiac magnetic resonance (CMR ...
Thiago Ferreira de Souza +13 more
doaj +1 more source
The Role of miRNAs in the Resistance of Anthracyclines in Breast Cancer: A Systematic Review
Frontiers in Oncology, 2022 Breast cancer has been reported as the most common cancer in women globally, with 2.26 million new cases in 2020. While anthracyclines are the first-line drug for breast cancer, they cause a variety of adverse reactions and drug resistance, especially ...
Zihan Si +10 more
doaj +1 more source
Maternal and Neonatal Complications Associated with Breast Cancer Systemic Treatments-A VigiBase Disproportionality Analysis Study. [PDF]
Clin Pharmacol TherPregnancy‐associated breast cancer (PrBC) presents therapeutic challenges. Understanding maternal–fetal safety of systemic anticancer therapies is critical. We performed a case/non‐case disproportionality analysis using the WHO global pharmacovigilance database up to January 2024, to evaluate maternal–fetal outcomes associated with breast cancer (BC ...
Kabirian R +12 more
europepmc +2 more sources
, 2022 Archive of anthracyclines containing sub-folders named after each compound and its net charge. Every compound's folder contains a total of 20 files distributed into three sub-directories reporting QM (QM/), FF (FF/), and MD (MD ...
Giuliano Malloci (2060875) +5 more
core +1 more source
Cardiotoxicity of Anthracyclines
Frontiers in Cardiovascular Medicine, 2020 Cardiotoxicity is a feared side effect that may limit the clinical use of anthracyclines. It may indeed affect the quality of life and survival of patients with cancer, regardless of oncological prognosis. This paper provides an overview of anthracycline-
Daniela Cardinale +2 more
doaj +1 more source
Pharmacogenomics and regulation of apoptosis in acute myeloid leukaemia [PDF]
Medicinski Podmladak, 2020 Acute myeloid leukaemia (AML) is a heterogenous clonal hematopoietic malignancy primarily treated with combination of cytarabine (ara-C) and anthracyclines. Despite high remission rates, especially in younger patients, a vast majority of patients die due
Pravdić Zlatko +1 more
doaj +1 more source
Cardiotoxic effects of anthracyclines in oncological treatment [PDF]
, 2023 Anthracyclines are antitumor antibiotics used during chemotherapy in cancer patients. Treatment with anthracyclines has good results but a side effect is significant cardiotoxicity.
Tekáčová, Kateřina
core +1 more source
TRP Channels: The Neglected Culprits in Breast Cancer Chemotherapy Resistance?
Membranes, 2023 Breast cancer is a major health concern worldwide, and resistance to therapies remains a significant challenge in treating this disease. In breast cancer, Transient Receptor Potential (TRP) channels are well studied and constitute key players in nearly ...
Mayar Soussi +2 more
doaj +1 more source
Clinics and Practice, 2021 Anthracycline-based regimens with or without anti-human epidermal growth factor receptor (HER) 2 agents such as trastuzumab are effective in breast cancer treatment. Nevertheless, heart failure (HF) has become a significant side effect of these regimens.
Jukapun Yoodee +5 more
doaj +1 more source
Anthracyclines: biosynthesis, engineering and clinical applications
, 2021 Covering: January 1995 to June 2021 Anthracyclines are glycosylated microbial natural products that harbour potent antiproliferative activities. Doxorubicin has been widely used as an anticancer agent in the clinic for several decades, but its use is ...
Hulst, M.B. +4 more
core +1 more source