Results 51 to 60 of about 6,366 (244)
Relationship between Chemotherapy and Atrial Fibrillation: Clinical Case
Рациональная фармакотерапия в кардиологии, 2021 The aim of this article is to represent the characterization of the clinical case of chemotherapy-related atrial fibrillation (AF) development in the young woman, elaborated as a result of multiple neoadjuvant and adjuvant modes of the intake of ...
A. A. Avagimyan +5 more
doaj +1 more source
Advanced Science, EarlyView.A multifunctional nanoagonist (cDZ@IP) enables nano‐metabolite–driven multimodal activation of the STING pathway and enhanced immune recognition, achieving potent antitumor immunity and suppressing tumor growth and metastasis. This strategy highlights the rational design of therapeutic metabolites and establishes a new paradigm bridging nanomedicine ...
Kepeng Hu +17 more
wiley +1 more source
Сhanges in Blood Pressure in Patients with Breast Cancer during Polychemotherapy with Anthracyclines
Львівський клінічний вісникIntroduction. Elevated blood pressure (BP) during treatment with anthracyclines, which include doxorubicin and epirubicin, may be a factor in polychemotherapy (PCT)-related cardiotoxicity, which necessitates monitoring and adjustment of BP in these ...
Світлана Бусел +4 more
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Reprogramming the Immune Landscape of Inflammatory Breast Cancer
Advanced Science, EarlyView.Inflammatory breast cancer is the most lethal subtype of breast cancer and is characterized by an immunosuppressive tumor microenvironment (TME) driven by a complex network of immune cells and inflammatory cytokines, contributing to its aggressiveness and treatment challenges. Immune checkpoint inhibitors, either alone or in combination, show potential
Verena Martinez‐Rodriguez +3 more
wiley +1 more source
Role of liposomal anthracyclines in breast cancer
, 2007 Anthracyclines are among the most effective drugs for patients with breast cancer. Their use, however, has been limited by associated toxic effects, including myelosuppression, alopecia, nausea and vomiting, stomatitis, and most importantly ...
Lorusso V., Silvestris N., Manzione L.
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Advanced Science, EarlyView.P3FI–90 treatment targets KDM3B, reshapes the epigenetic landscape, and suppresses SHP1 expression, thereby activating STING–TBK1–IRF3–type I IFN signaling pathway. Consequently, CD8+ T cells are recruited to the tumor site and activated to produce IFN–γ and GZMB, leading to the killing of TNBC cells.
Xiaolong Wang +8 more
wiley +1 more source
Asymmetric Synthesis of Anticancer Anthracyclines PhD thesis
, 2014 Some of the experimental part from my PhD thesis entitled 'Asymmetric Synthesis of Anticancer Anthracyclines', University of Manchester, U.K., 1994. Author Jonathan P. Miller.
Miller, Jonathan
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Advanced Science, EarlyView.This study presents a surfaceome‐reprogramming strategy for mutation‐independent lung cancer therapy by repurposing dexamethasone to prime mesenchymal stem cell‐derived nanovesicles. The engineered vesicles leverage multi‐valent interactions mediated by upregulated adhesion proteins, EPHA2, and NOTCH3.
Geunhye Kim +8 more
wiley +1 more source
Predictive and Prognostic Relevance of ABC Transporters for Resistance to Anthracycline Derivatives
BiomoleculesAnthracyclines have been clinically well established in cancer chemotherapy for decades. The main limitations of this drug class are the development of resistance and severe side effects.
Rümeysa Yücer +5 more
doaj +1 more source
Antitumour Drug Induced Cardiovascular Toxicity and Current Tumour Treatment Methods
Креативная хирургия и онкология, 2020 Currently the oncological mortality takes the second place globally, the leading cause being cardiovascular diseases. The statistics of malignant neoplasms is rather negative all over the world.
K. S. Gumerova +2 more
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