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Dapsone hypersensitivity syndrome (DHS) is characterized by fever, skin rash, eosinophilia, lymphadenopathy, and multi systemic manifestations following Dapsone therapy [1].
S. P. N. Weerasekara+4 more
doaj +1 more source
Gentian violet for pyoderma gangrenosum: a retrospective chart review [PDF]
Pyoderma gangrenosum is a rare autoinflammatory skin disease. Treatment is multifactorial, addressing inflammation, pain, underlying disease, if present, and the wound.
Cline, A+6 more
core
Evaluation of early and late presentation of patients with ocular mucous membrane pemphigoid to two major tertiary referral hospitals in the United Kingdom [PDF]
PURPOSE: Ocular mucous membrane pemphigoid (OcMMP) is a sight-threatening autoimmune disease in which referral to specialists units for further management is a common practise.
AH Ross+45 more
core +2 more sources
Dapsone has been used in the treatment of bullous pemphigoid (BP) for over 50 years. According to the 2015 European Recommendations, the treatment of choice in BP are potent topical corticosteroids. In this article, we present data from the literature on
Magdalena Żychowska+3 more
doaj +1 more source
Background: Leprosy is a neglected tropical disease affecting millions of people. The current treatment against leprosy includes various antibacterial drugs of which dapsone is known to bind to dihydropteroate synthase of Mycobacterium leprae. Dapsone is
Sumit T Halder+3 more
doaj +1 more source
After the injection of about 10 gm of dapsone, a 38-year-old male showed a whitish-yellow patch in the macular region of both eyes, with decreased visual acuity of the counting finger in the right and 0.04 in the left eye. Two weeks after the start of systemic steroid therapy the patch disappeared, and on follow-up at 11 months, visual acuity was 0.02 ...
M S, Seo, K C, Yoon, Y G, Park
openaire +2 more sources
Dapsone syndrome with acute renal failure during leprosy treatment: case report
Dapsone syndrome is a rare hypersensitivity reaction to dapsone and is characterized by high fever, papular or exfoliative dermatitis, progressing to liver toxicity and generalized lymphadenopathy, resembling a mononucleosis infection.
Edson Nogueira Alves-Rodrigues+4 more
doaj +1 more source
Objective The objective of this study was to investigate the effect of prophylactic trimethoprim‐sulfamethoxazole (TMP‐SMX) on the incidence of serious infections in patients with antineutrophil cytoplasmic antibody–associated vasculitis (AAV). Methods This multicenter cohort study was designed to emulate a target trial that studied 296 patients with ...
Yun Kyu Kim+7 more
wiley +1 more source
Addressing the challenge of neonatal mortality.
Reducing neonatal mortality remains a challenge with an estimated 3.0 million neonatal deaths in 2011, three-quarters of these in sub-Saharan Africa and Southern Asia.
Blencowe, H, Cousens, S
core +1 more source
Voclosporin‐induced gingival enlargement: A case report
Abstract Background Drug‐influenced gingival enlargement (DIGE) is a recognized adverse effect of certain medications, particularly immunosuppressants like cyclosporin and tacrolimus. However, there have been no documented cases of DIGE associated with voclosporin, a newer calcineurin inhibitor used primarily to treat lupus nephritis.
Francesca Racca+2 more
wiley +1 more source