Results 31 to 40 of about 11,723 (189)
Dapsone Alters Phenotypical and Functional Properties of Human Neutrophils In Vitro
MoleculesDapsone is a sulfone used in treating inflammatory skin conditions. Despite its widespread dermatological use, the pharmacological actions of dapsone remain poorly understood.
Sara Rakočević +7 more
doaj +1 more source
Dermatologica Sinica, 2011 Dapsone (4,4′-diaminodiphenylsulfone) has been used for a variety of dermatological conditions. Dapsone-induced drug reaction with eosinophilia and systemic symptoms (DRESS) is a rare but severe drug reaction characterized by fever, cutaneous eruption ...
Wei-Hsuan Li, Han-Nan Liu, Ding-Dar Lee
doaj +1 more source
JPGN Reports, EarlyView.Abstract Skin and lung findings, including the rare findings of leukocytoclastic vasculitis (LCV) and necrobiotic pulmonary nodules, are known extraintestinal manifestations (EIMs) of inflammatory bowel disease. However, these rare EIMs have typically been reported as being a sign of active intestinal disease.
Joshua D. Noe +3 more
wiley +1 more source
Surgical Reconstruction in Pyoderma Gangrenosum, a Retrospective Study of Five Patients
JEADV Clinical Practice, EarlyView.ABSTRACT Pyoderma Gangrenosum (PG) is a neutrophilic dermatosis characterized by chronic painful ulcerations most commonly on the lower extremities. Current treatment options for PG are largely nonsurgical and include the use of systemic and topical immunomodulators and wound care.
Max E. Oscherwitz +8 more
wiley +1 more source
Sulfone Syndrome: A Unique Delayed Type of Drug Hypersensitivity from Dapsone
Journal of Health Science and Medical Research (JHSMR)Nowadays, dapsone is more commonly used in some dermatologic and inflammatory conditions other than leprosy. Even though it has excellent therapeutic efficacy, its side effects are of common concern. Although immune mediated drug hypersensitivity is less
Metus Thungthienthong +2 more
doaj +1 more source
Risk factors for dapsone resistance in leprosy patients: a systematic meta-analysis
Journal of Global Antimicrobial Resistance, 2022 : Objectives: Dapsone is one of the important drugs in the treatment of leprosy. The present study aims to evaluate the resistance of Mycobacterium leprae isolates to dapsone, in turn assisting in implementing better control strategies for leprosy ...
Ziwei Wu +5 more
doaj +1 more source
JEADV Clinical Practice, EarlyView.ABSTRACT Background Epidermal necrolysis (EN), including Stevens‐Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), are severe cutaneous drug reactions with high morbidity. However, the quality of life (QoL) impact during acute hospitalization is not well understood.
Jacob McFeeters +9 more
wiley +1 more source
Marshall Journal of Medicine, 2016 Dapsone is a Leprostatic agent routinely used for Malaria, Leprosy and as a prophylaxis for Pneumocystis jiroveci pneumonia (PCP), as well as Toxoplasma gondii in immunocompromised patients.
Ahlim Al Sanani
doaj +1 more source
JTO Clinical and Research Reports, 2022 A 45-year-old woman with a history of lung adenocarcinoma treated with osimertinib developed purpuric plaques and vesicles on the lower extremities after 5 months of therapy. Skin biopsy revealed leukocytoclastic vasculitis (LCV).
Christopher Iriarte, MD +3 more
doaj +1 more source
Response to Oral Dapsone in a Patient With Generalised Junctional Epidermolysis Bullosa
JEADV Clinical Practice, EarlyView.ABSTRACT Dapsone is a potent antibacterial agent used as a first‐line treatment for leprosy and employed also as an anti‐inflammatory agent. Additionally, dapsone is used for a variety of other cutaneous conditions. Herein, we report a case of intermediate junctional epidermolysis bullosa that improved significantly with oral 4,4’‐diamino‐diphenyl ...
Shiho Mori +2 more
wiley +1 more source