Results 11 to 20 of about 3,924 (164)
Introduction: Dapsone syndrome is a distinct hypersensitivity reaction characterized by skin rash, fever, generalized lymphadenopathy, hepatosplenomegaly and hepatitis which subside with cessation of dapsone therapy.
J Sridhar
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Dapsone has been used in the treatment of bullous pemphigoid (BP) for over 50 years. According to the 2015 European Recommendations, the treatment of choice in BP are potent topical corticosteroids. In this article, we present data from the literature on
Magdalena Żychowska +3 more
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Methemoglobinemia and dapsone levels in patients with leprosy [PDF]
The objective of this work was to determine the methemoglobinemia and correlate with dapsone levels in multibacillary leprosy patients under leprosy multi-drug therapy. Thirty patients with laboratory and clinical diagnosis of multibacillary leprosy were
Jose Luiz Fernandes Vieira +4 more
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Adverse reactions in leprosy patients who underwent dapsone multidrug therapy: a retrospective study
Sanjeev Guragain,1 Namrata Upadhayay,2 Bishwa Mohan Bhattarai3 1Department of Pharmacology, Gandaki Medical College Teaching Hospital and Research Centre, Lekhnath, 2Department of Physiology, Gandaki Medical College Teaching Hospital and Research ...
Guragain S, Upadhayay N, Bhattarai BM
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Lidiane M Monteiro,1 Viviane F Lione,1 Flavia A do Carmo,1 Lilian H do Amaral,1 Julianna H da Silva,2 Luiz E Nasciutti,2 Carlos R Rodrigues,1 Helena C Castro,3 Valeria P de Sousa,1 Lucio M Cabral11Faculdade de Farmácia, Universidade Federal do
Monteiro LM +9 more
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An unusual case of dapsone syndrome
Dapsone, a potent antiparasitic and anti-inflammatory compound, is mainly used in the treatment of leprosy and a variety of blistering skin diseases.
Mary Grace
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Cimetidine improves the therapeutic/toxic ratio of dapsone in patients on chronic dapsone therapy
We have previously shown that cimetidine, given concurrently for 2 weeks to patients on chronic dapsone therapy, reduced methaemoglobinaemia by inhibiting the formation of the toxic hydroxylamine metabolite of dapsone. The aim of the present study was to
Friedmann, P. S. +5 more
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AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Dapsone (4,4'-diaminodiphenylsulfone, DDS) was synthesized a century ago and continues to be a powerful therapeutic tool in many skin diseases. We have tried to retrieve and present the available knowledge and relevant information on this old but still very useful drug with the hope of encouraging and guiding practicing dermatologists to adapt it for ...
Wolf, Ronni +4 more
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The appearance of bite cells associated with methemoglobinemia can be caused by oxidizing drugs such as dapsone in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency or high drug serum levels. Bite cells are often pathognomonic for oxidant
Gandelman, Jocelyn S +15 more
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