Results 1 to 10 of about 14,442 (214)
Frontiers in Immunology, 2021 HLA-B*13:01 allele has been identified as the genetic determinant of dapsone hypersensitivity syndrome (DHS) among leprosy and non-leprosy patients in several studies.
Therdpong Tempark +2 more
exaly +3 more sources
Treatment of a life-threatening dapsone intoxication [PDF]
Toxicology Reports, 2023 The case report describes a case of a severe dapsone (more than 200 tablets dapsone 100 mg) and mild methotrexate intoxication (10 tablets methotrexate 10 mg) as an attempt to commit suicide, resulting in severe cyanosis with elevation in methemoglobin ...
M.H. Veerman +3 more
doaj +3 more sources
Safety and effectiveness of topical dapsone in acne treatment: A review [PDF]
Journal of Family Medicine and Primary CareOral dapsone is effective in treating several dermatologic conditions, including acne vulgaris. However, the rate of adverse effects of oral dapsone is a concern when prescribing it.
Sami N. Alsuwaidan, Tala A. Qadoumi
doaj +2 more sources
Dapsone is an anticatalysis for Alzheimer’s disease exacerbation [PDF]
iScience, 2022 Summary: Brain inflammation generally accelerates neurodegeneration. Alzheimer’s disease (AD) triggers an innate immune response by activating a cytosolic DNA sensor cyclic-GMP-AMP synthase (cGAS)/stimulator of interferon genes (STING) signaling pathway.
Jong Hoon Lee +4 more
doaj +3 more sources
DAPSONE-INDUCED TOXIC MACULOPATHY IN LEPROSY PATIENT [PDF]
IJRETINA (International Journal of Retina), 2023 Introduction: Dapsone has been widely used as a part of multidrug therapy for leprosy patients. Ocular side effects are rare. Ocular toxicity manifestations include retinal necrosis, optic atrophy, macular infarction, bilateral exudative retinal ...
Sita Paramita Ayuningtyas +4 more
doaj +4 more sources
Dermatologic Therapy, 2002 Dapsone (4,4'-diaminodiphenylsulfone, DDS) was synthesized a century ago and continues to be a powerful therapeutic tool in many skin diseases. We have tried to retrieve and present the available knowledge and relevant information on this old but still very useful drug with the hope of encouraging and guiding practicing dermatologists to adapt it for ...
Wolf, Ronni +4 more
exaly +5 more sources
Dapsone-induced methemoglobinemia in gynecologic cancer patients treated with immune checkpoint Inhibitors: a case series [PDF]
Gynecologic Oncology ReportsBackground: Immune checkpoint inhibitors (ICI) activate antitumor immunity which can lead to the development of immune-related adverse events (irAE) that often require management with high-dose corticosteroids.
Julia C. Sakach +6 more
doaj +2 more sources
Dapsone-Induced Granulomatous Cholestatic Hepatitis Unmasked by Steroid Taper: A Case Report
Case Reports in Gastroenterology, 2023 Introduction: Dapsone is known to cause drug-induced liver injury (DILI) but can rarely induce the formation of hepatic granulomas. We describe a patient with jaundice who demonstrated granulomas on liver biopsy in response to dapsone.
Shahana Prakash +2 more
doaj +1 more source
Acta Medica Iranica, 2021 Several factors contribute to the development of gastric erosions, including corticosteroids and nonsteroidal anti-inflammatory drugs (NSAIDs), alcohol, and stress.
Mohammad Sheibani +4 more
doaj +1 more source
International Journal of Retina and Vitreous, 2022 Background Dapsone is a synthetic sulfonamide used to treat numerous dermatologic conditions. Ocular side effects have been rarely reported and include retinal necrosis, optic atrophy, and macular infarction.
Sarah P. Dugan, Hakan Demirci
doaj +1 more source