Treatment of refractory IgA vasculitis with dapsone: a systematic review [PDF]
IgA vasculitis, formerly known as Henoch-Schönlein purpura, is a systemic IgA-mediated vasculitis of the small vessels commonly seen in children. The natural history of IgA vasculitis is generally self-limiting; however, one-third of patients experience ...
Keum Hwa Lee +11 more
doaj +1 more source
Randomized trial of artesunate+amodiaquine, sulfadoxine-pyrimethamine+amodiaquine, chlorproguanal-dapsone and SP for malaria in pregnancy in Tanzania. [PDF]
BACKGROUND: Malaria in pregnancy is serious, and drug resistance in Africa is spreading. Drugs have greater risks in pregnancy and determining the safety and efficacy of drugs in pregnancy is therefore a priority.
Greenwood, Brian M +24 more
core +1 more source
DAPSONE HYPERSENSITIVITY SYNDROME - A CASE REPORT AT TERTIARY CARE HOSPITAL [PDF]
Dapsone a sulfonamide drug used mainly in the treatment of Leprosy and various other several bacterial infections. Rarely Dapsone can lead to hypersensitive reaction characterised by fever, yellowish sclera and other systems involved. We report a 17 year
Sailajapriyadarsini Parlapalli , Sekhar Babu Bandar +1 more
core +1 more source
Clinical outcomes of adverse cardiovascular events in patients with acute dapsone poisoning [PDF]
Objective Adverse cardiovascular events (ACVEs) account for a large proportion of the morbidities and mortalities associated with drug overdose emergencies. However, there are no published reports regarding outcomes of ACVEs associated with acute dapsone
Kyung Sik Kang +7 more
doaj +1 more source
Dapsone hypersensitivity syndrome (DHS) is characterized by fever, skin rash, eosinophilia, lymphadenopathy, and multi systemic manifestations following Dapsone therapy [1].
S. P. N. Weerasekara +4 more
doaj +1 more source
Dapsone hypersensitivity syndrome-rare complication of dapsone therapy [PDF]
Among several other adverse effects of dapsone therapy, dapsone hypersensitivity syndrome is extremely rare but most life-threatening complication.
Parvaiz A. Shah +7 more
core +2 more sources
DAPSONE HYPERSENSITIVITY SYNDROME: A COMPLICATION OF DAPSONE THERAPY [PDF]
Dapsone is chemically sulfonamide with its leprostatic mechanism used in the treatment of Hansen’s disease. It is one of the safest drugs in leprosy patients.
GUNTURU, LAKSHMI NARASIMHA +3 more
core +1 more source
Dapsone induced hypersensitivity syndrome: a case report [PDF]
Dapsone is an anti-leprotic drug. It may cause a severe adverse effect known as dapsone hypersensitivity syndrome which involves fever, chills, rash, and internal organ involvement.
Suhagiya, Priyanka, Kolli, Sarika
core +2 more sources
Inhibition of Dapsone-Induced Methaemoglobinaemia by Cimetidine in the Rat During Chronic Dapsone Administration [PDF]
Dapsone undergoes N-acetylation to monoacetyl dapsone as well as N-hydroxylation to a hydroxylamine which is responsible for the haemotoxicity (i.e. methaemoglobinaemia; Met Hb) of the drug. Since dapsone is always given chronically, we have investigated
M D Coleman, B K Park, M D Tingle
core +1 more source
Dapsone syndrome with acute renal failure during leprosy treatment: case report
Dapsone syndrome is a rare hypersensitivity reaction to dapsone and is characterized by high fever, papular or exfoliative dermatitis, progressing to liver toxicity and generalized lymphadenopathy, resembling a mononucleosis infection.
Edson Nogueira Alves-Rodrigues +4 more
doaj +1 more source

