Results 31 to 40 of about 3,924 (164)

Clinical outcomes of adverse cardiovascular events in patients with acute dapsone poisoning [PDF]

Clinical and Experimental Emergency Medicine, 2016
Objective Adverse cardiovascular events (ACVEs) account for a large proportion of the morbidities and mortalities associated with drug overdose emergencies. However, there are no published reports regarding outcomes of ACVEs associated with acute dapsone
Kyung Sik Kang, Hyung Il Kim, Oh Hyun Kim, Kyoung Chul Cha, Hyun Kim, Kang Hyun Lee, Sung Oh Hwang, Yong Sung Cha   +7 more
doaj   +1 more source

Dapsone hypersensitivity syndrome-rare complication of dapsone therapy [PDF]

, 2017
Among several other adverse effects of dapsone therapy, dapsone hypersensitivity syndrome is extremely rare but most life-threatening complication.
Parvaiz A. Shah, Muzaffar Maqbool, Rakesh K. Koul, Wani, Fayaz A., Fayaz A. Wani, Maqbool, Muzaffar, Shah, Parvaiz A., Koul, Rakesh K.   +7 more
core   +1 more source

Dapsone-CYP 2C19 complex.

, 2018
Dapsone is shown in spheres and the target enzyme is colored from blue, starting from terminal N, through the red, up until terminal C (a). Dapsone-catalytic site CYP2C19 complex: Dapsone, the interacting amino acid residues and heme prosthetic group ...
Fabio R. Oliveira (512808), Jose Luiz F. Vieira (512806), Pedro R. T. Romão (512807), Rosivaldo S. Borges (512803), Claudio G. Salgado (512805), Michael D. Coleman (312824), João Batista Júnior (512804), Marta Chagas Monteiro (512809), Taysa Ribeiro Schalcher (512802)   +8 more
core   +1 more source

Multiple docking analysis and In silico absorption, distribution, metabolism, excretion, and toxicity screening of anti-leprosy phytochemicals and dapsone against dihydropteroate synthase of Mycobacterium leprae

International Journal of Mycobacteriology, 2019
Background: Leprosy is a neglected tropical disease affecting millions of people. The current treatment against leprosy includes various antibacterial drugs of which dapsone is known to bind to dihydropteroate synthase of Mycobacterium leprae. Dapsone is
Sumit T Halder, Tehseen M Dhorajiwala, Lalit R Samant,   +3 more
doaj   +1 more source

Dapsone syndrome with acute renal failure during leprosy treatment: case report

Brazilian Journal of Infectious Diseases
Dapsone syndrome is a rare hypersensitivity reaction to dapsone and is characterized by high fever, papular or exfoliative dermatitis, progressing to liver toxicity and generalized lymphadenopathy, resembling a mononucleosis infection.
Edson Nogueira Alves-Rodrigues, Luciano Correa Ribeiro, Margareth Dióz Silva, Arley Takiuchi, Cor Jesus Fernandes Fontes   +4 more
doaj   +1 more source

Dispensing of actionable pharmacogenetic drugs among adults receiving cardiovascular disease medications in the Northern Netherlands: A serial cross‐sectional study

Clinical Pharmacology &Therapeutics, EarlyView.
The extent of pharmacogenetic (PGx) drug dispensing among Dutch adults receiving medications for cardiovascular disease (CVD) is unknown. Using the University of Groningen IADB.nl pharmacy database, we performed a serial cross‐sectional study (2019–2023) to estimate the annual prevalence of PGx drug dispensing and annual rates of initiation.
Zhuolin Zhang, Guiling Zhou, Jens H. J. Bos, Eelko Hak, Talitha Feenstra, Frank Klont   +5 more
wiley   +1 more source

Falsely decreased HbA1c in a type 2 diabetic patient treated with dapsone

, 2014
Glycated hemoglobin A1c (HbA1c) is an important indicator of glycemic control. The current recommendation for glycemic control based on HbA1c values has been widely accepted.
Lai, Ying-Chuen;Wang, Chou-Shiang;Wang, Yi-Ching;Hsu, Yu-Ling;Chuang, Lee-Ming, 莊立民   +1 more
core   +1 more source

Early-Onset Methemoglobinemia in an HIV Patient Receiving Dapsone for PCP Prophylaxis Without G6PD Deficiency: A Case Report

Mediterranean Journal of Infection, Microbes and Antimicrobials
Dapsone is used for Pneumocystis jirovecii pneumonia (PCP) prophylaxis in patients with human immunodeficiency virus (HIV) infection who cannot tolerate trimethoprim–sulfamethoxazole (TMP-SMX), the first-line agent.
Deniz Kakalıçoğlu Özden, Canan Cengiz, Ece Öztürk Çiftci, Filiz Pehlivanoğlu   +3 more
doaj   +1 more source

Nail Lichen Planus in Children ‐ Epidemiology, Pathogenesis, Clinical Presentation, and Treatment

JEADV Clinical Practice, EarlyView.
ABSTRACT Nail lichen planus (NLP) is a chronic inflammatory disorder that, while rare in children compared to adults, represents a significant cause of pediatric nail dystrophy that requires early recognition to prevent permanent scarring and nail loss.
Francesca Pampaloni, Matilde Iorizzo
wiley   +1 more source

Dapsone Alters Phenotypical and Functional Properties of Human Neutrophils In Vitro

Molecules
Dapsone is a sulfone used in treating inflammatory skin conditions. Despite its widespread dermatological use, the pharmacological actions of dapsone remain poorly understood.
Sara Rakočević, Vanja Mališ, Ljiljana Kozić, Anđela Dubovina, Marija Drakul, Dejan Bokonjić, Miodrag Čolić, Dušan Mihajlović   +7 more
doaj   +1 more source