Results 61 to 70 of about 25,202 (260)

The Role of Arterial Blood Gas in Distinction of Intravascular Hemolysis in a Patient with Lupus Nephritis

open access: yesMarshall Journal of Medicine, 2016
Dapsone is a Leprostatic agent routinely used for Malaria, Leprosy and as a prophylaxis for Pneumocystis jiroveci pneumonia (PCP), as well as Toxoplasma gondii in immunocompromised patients.
Ahlim Al Sanani
doaj   +1 more source

Recovery of Dementia Syndrome following Treatment of Brain Inflammation

open access: yesDementia and Geriatric Cognitive Disorders Extra, 2020
Aim/Background: This research aims to prevent progression from mild cognitive impairment (MCI) to Alzheimer’s disease. A Japanese study of leprosy patients revealed that the incidence of dementia in leprosy patients was lower than that in patients taking
Jong-hoon Lee   +3 more
doaj   +1 more source

Efficacy and safety of dapsone as second line therapy for adult immune thrombocytopenia: A retrospective study of 42 patients. [PDF]

open access: yesPLoS ONE, 2017
Dapsone is recommended as a second line therapy in immune thrombocytopenia (ITP), but is underused because of its potential side effects. The medical charts of 42 ITP patients treated with dapsone (100 mg/day) were retrospectively reviewed in order to ...
Clémentine Estève   +7 more
doaj   +1 more source

Impact of Mechanistic Modeling and Simulation Methodologies on Product‐Specific Guidance Development for Non‐Orally Administered Drug Products

open access: yesCPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT The U.S. Food and Drug Administration (FDA) publishes product‐specific guidances (PSGs), with bioequivalence (BE) recommendations for prospective generics. Developing BE recommendations for non‐orally administered drug products including long‐acting injectables (LAI), orally inhaled drug products, and drugs applied locally to the skin ...
Steven G. Chopski   +6 more
wiley   +1 more source

Atovaquone Compared with Dapsone for the Prevention of Pneumocystis carinii Pneumonia in Patients with HIV Infection Who Cannot Tolerate Trimethoprim, Sulfonamides, or Both [PDF]

open access: yes, 1998
BACKGROUND Although trimethoprim–sulfamethoxazole is the drug of choice for the prevention of Pneumocystis carinii pneumonia, many patients cannot tolerate it and must switch to an alternative agent.
Balfour, Henry H., , Jr., M.D.   +11 more
core   +1 more source

Opportunities and Challenges of Population Pharmacogenomics

open access: yesAnnals of Human Genetics, EarlyView.
ABSTRACT Pharmacological responses can vary significantly among patients from different ethnogeographic backgrounds. This variability can, at least in part, be attributed to population‐specific genetic patterns in genes involved in drug absorption, distribution, metabolism, and excretion, as well as in genes associated with drug‐induced toxicity ...
Yitian Zhou   +3 more
wiley   +1 more source

Ocular manifestations in lepromatous and tuberculoid leprosy [PDF]

open access: yes, 1990
Ocular manifestations of leprosy in 100 patients examined were reported on; -80% were suffering from the lepromatous type of the disease. The most frequent change was loss of eyebrows (40%) which was seen mainly in lepromatous patients.
Blagojevic, Milan   +4 more
core  

Severe dapsone hypersensitivity syndrome in a child [PDF]

open access: yesKorean Journal of Pediatrics, 2013
Dapsone (4,4'-diaminodiphenylsulfone, DDS), a potent anti-inflammatory agent, is widely used in the treatment of leprosy and several chronic inflammatory skin diseases.
So Yoon Choi   +4 more
doaj   +1 more source

The Genetics of Acne

open access: yesAnnals of Human Genetics, EarlyView.
ABSTRACT This review addresses the genetics of acne vulgaris, the most common skin disease. It is characterized by the presence of comedones (blackheads), papules, and pustules. The condition is associated with sebaceous glands in the face and chest, which produce an oily substance called sebum.
Maurice A. M. Van Steensel
wiley   +1 more source

Pyoderma Gangrenosum Masquerading as Necrotizing Fasciitis: Stepping Away from Cognitive Shortcuts [PDF]

open access: yes, 2017
A patient with post-Cesarean wound complication was treated for necrotizing fasciitis (NF) with sharp debridement and broad-spectrum antibiotics. Several operations and three weeks later, her abdominal skin, subcutaneous fat, right-sided rectus abdominus,
Berryman, Jefferson   +2 more
core   +2 more sources

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