Results 71 to 80 of about 3,924 (164)

Management of chronic urticaria: Current status and future prospect

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Chronic urticaria is driven by mast cell activation through autoimmune, inflammatory, and neuroimmune pathways. A structured approach combining diagnosis, patient‐reported outcomes, stepwise therapy, treatment optimization, monitoring and emerging targeted agents may improve disease control and enable more personalized management.
Andaç Salman, Mona Al‐Ahmad, Maryam Al‐Nesf, Chia‐Yu Chu, Luis Felipe Ensina, Ana M. Gimenez‐Arnau, Margarida Gonçalo, Clive Grattan, Michihiro Hide, Pavel Kolkhir, Martin Metz, Iman Nasr, Romi Saini, Simon Francis Thomsen, Torsten Zuberbier, Emek Kocaturk   +15 more
wiley   +1 more source

Dapsone Suppresses Integrin-Mediated Neutrophil Adherence Function [PDF]

, 1992
The anti-inflammatory influence of dapsone may involve suppression of neutrophil chemotaxis to selected attractants, but other actions of the drug are likely also involved.
Dahl, Mark V, Charles E Moody, Herron, Michael J, Sally A Booth, Booth, Sally A, Robert D Nelson, Moody, Charles E, Michael J Herron, Nelson, Robert D, Mark V Dahl   +9 more
core   +1 more source

DAPSONE HYPERSENSITIVITY SYNDROME - A CASE REPORT AT TERTIARY CARE HOSPITAL

, 2022
Dapsone a sulfonamide drug used mainly in the treatment of Leprosy and various other several bacterial infections. Rarely Dapsone can lead to hypersensitive reaction characterised by fever, yellowish sclera and other systems involved. We report a 17 year
Sailajapriyadarsini Parlapalli , Sekhar Babu Bandar, Upendra Kumar Mudragadda   +1 more
core   +1 more source

Recovery of Dementia Syndrome following Treatment of Brain Inflammation

Dementia and Geriatric Cognitive Disorders Extra, 2020
Aim/Background: This research aims to prevent progression from mild cognitive impairment (MCI) to Alzheimer’s disease. A Japanese study of leprosy patients revealed that the incidence of dementia in leprosy patients was lower than that in patients taking
Jong-hoon Lee, Su-hee Choi, Chul Joong Lee, Sang-suk Oh   +3 more
doaj   +1 more source

Efficacy and safety of high doses of eltrombopag for treating adult immune thrombocytopenia: Results from a multicentre retrospective cohort study

British Journal of Haematology, EarlyView.
Salomé Dahan, Stéphanie Guillet, Olivier Fain, Delphine Gobert, Stéphane Cheze, Florent Broca, Bertrand Godeau, Marc Michel   +7 more
wiley   +1 more source

Treatment strategies for interstitial granulomatous dermatitis: Systematic review and expert opinion

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Systematic review of 108 studies with a total of 182 patients with interstitial granulomatous dermatitis (IGD). IGD was frequently associated with systemic conditions or drug exposure. Management includes careful medication review and prompt withdrawal of potential triggers. Corticosteroids (systemic and topical) were commonly effective, while biologic
Francesco Bellinato, Sara Salvagno, Chiara Colato, Paolo Gisondi, Giampiero Girolomoni   +4 more
wiley   +1 more source

Dapsone- and nitroso dapsone-specific activation of T-cells from hypersensitive patients expressing the risk allele HLA-B*13:01. [PDF]

, 2019
BACKGROUND:Research into drug hypersensitivity associated with expression of specific HLA alleles has focussed on the interaction between parent drug and the HLA with no attention given to reactive metabolites.
Mubarak Almutairi, Zhang, Huimin, Liu, Jianjun, Abdulaziz Alzahrani, Lele Sun, Monday O. Ogese, Khetam Alhilali, Jianjun Liu, Dean J. Naisbitt, Andrew Gibson, Gibson, Andrew, Sun, Yonghu, Xiaoli Meng, Ogese, Monday O, Yonghu Sun, David A. Ostrov, Hong Liu, Zhao, Qing, Zhang, Furen, Ostrov, David A, Huimin Zhang, Qing Zhao, Liu, Hong, Furen Zhang, Juwaria Amjad, Sun, Lele, Alhilali, Khetam, Naisbitt, Dean J, Almutairi, Mubarak, Amjad, Juwaria, B. Kevin Park, Meng, Xiaoli, Alzahrani, Abdulaziz, Park, B Kevin   +33 more
core   +1 more source

Sustained Remission of Pediatric Bowel‐Associated Dermatosis‐Arthritis Syndrome With Risankizumab

Pediatric Dermatology, EarlyView.
ABSTRACT Bowel‐associated dermatosis‐arthritis syndrome (BADAS) is a rare neutrophilic dermatosis characterized by recurrent fever, arthralgias, and skin eruptions, most commonly occurring in patients with inflammatory bowel disease. We report the case of a 17‐year‐old female with Crohn's disease who developed BADAS and achieved complete and durable ...
Kylie E. Peake, Harman Toor, Marie‐Christine Jean, Collin C. Barker, Joseph M. Lam   +4 more
wiley   +1 more source

Aortic dissection type A, common carotid artery occlusion, and stroke after dapsone for 20 years

Journal of Family Medicine and Primary Care
Long-term use of dapsone, a sulfone with anti-inflammatory and immunosuppressive properties, has not been previously reported in association with aortic dissection type A.
Josef Finsterer, Sounira Mehri
doaj   +1 more source

Optimizing Pneumocystis jirovecii Prophylaxis in Immunocompromised Patients: Defining the Clinical Role of Atovaquone

Transplant Infectious Disease, EarlyView.
In a retrospective cohort study of 149 patients receiving atovaquone for PJP prophylaxis, increased usage was related to broader indications, uptake in new patient groups, difficulty tolerating or accessing alternatives, and longer durations used per patient.
To N. Pham, Kelly A. Cairns, Adithi Ramachandra, Susan G. Poole, Carmela E. Corallo, Bradley J. Gardiner   +5 more
wiley   +1 more source