Results 61 to 70 of about 5,151 (200)

Quantification of polysorbate 80 in biopharmaceutical formulations implementing an optimized colorimetric approach

open access: yesТонкие химические технологии, 2020
Objectives. We hereby describe an improvement of a previously developed quantification technique for polysorbate 80 in biopharmaceutical formulations (darbepoetin alfa and eculizumab) and report the validation of the new approach.Methods. Polysorbate was
A. S. Seregin   +4 more
doaj   +1 more source

Staff Time and Motion Assessment for Administration of Erythropoiesis-Stimulating Agents: A Two-Phase Pilot Study in Clinical Oncology Practices [PDF]

open access: yes, 2013
BACKGROUND: Erythropoiesis-stimulating agents (ESAs) are used for the management of anaemia in patients with non-myeloid malignancies where anaemia is due to the effect of concomitant myelosuppressive chemotherapy.
Arletta van Breda   +5 more
core   +1 more source

Cost Minimized Immunoaffinity Purification of EPO and Its Analogs in Doping Control—A Step‐by‐Step Protocol for Human Urine and Blood

open access: yesDrug Testing and Analysis, Volume 17, Issue 9, Page 1545-1559, September 2025.
A cost minimized immunoaffinity protocol was developed, which allows the direct purification of ERAs from human urine. After slight modification, the protocol is also applicable to serum and plasma and is fully compliant with WADA TD2024EPO. Compared to commercial EPO‐purification kits, the material costs are significantly lower.
Christian Reichel   +2 more
wiley   +1 more source

Evaluating Economic and Clinical Impacts of Anaemia Management Strategies: A Systematic Review of the Evidence From the UK Perspective

open access: yeseJHaem, Volume 6, Issue 4, August 2025.
ABSTRACT Background Anaemia significantly affects health outcomes and quality of life. While blood transfusion remains a common intervention, alternative treatments, such as iron supplementation and erythropoiesis‐stimulating agents (ESAs), offer potential to mitigate transfusion‐associated costs.
Hiro Farabi   +9 more
wiley   +1 more source

Carnitine reduced erythropoietin dose required and improved cardiac function of patients on maintenance hemodialysis

open access: yesSaudi Journal of Kidney Diseases and Transplantation, 2017
Intravenous administration of 2 g carnitine in every hemodialysis (3 times/week), for 8–10 months, reduced doses of darbepoetin alfa required to maintain adequate hemoglobin levels (10–11 g/dL) into 10% of the initial doses.
Yosuke Aoki, Takako Yamamoto
doaj   +1 more source

ERYTHROPOIETIN FOR THE TREATMENT OF SUBARACHNOID HEMORRAGE: A FEASIBLE INGREDIENT FOR A SUCCESS MEDICAL RECIPE [PDF]

open access: yes, 2015
Subaracnhoid hemorrage (SAH) following aneurysm bleeding accounts for 6% to 8% of all cerebrovascular accidents. Althoug an aneurysm can be effectively managed by surgery or endovascular therapy, delayed cerebral ischemia is diagnosed in a high ...
A Gorio   +101 more
core   +1 more source

How to use luspatercept and erythropoiesis‐stimulating agents in low‐risk myelodysplastic syndrome

open access: yesBritish Journal of Haematology, Volume 207, Issue 1, Page 15-26, July 2025.
Summary Anaemia is the most common cytopenia in myelodysplastic syndrome (MDS), significantly impacting quality of life and morbidity. Erythropoiesis‐stimulating agents (ESAs) are the first‐line treatment for anaemia in lower risk (LR)‐MDS. The European Medicines Agency (EMA) approved epoetin alpha for LR‐MDS‐related anaemia in 2017, based on evidence ...
Valeria Santini, Angela Consagra
wiley   +1 more source

Uptake of evidence by physicians: De-adoption of erythropoiesis-stimulating agents after the TREAT trial

open access: yesBMC Nephrology, 2021
Background Variation in de-adoption of ineffective or unsafe treatments is not well-understood. We examined de-adoption of erythropoiesis-stimulating agents (ESA) in anemia treatment among patients with chronic kidney disease (CKD) following new clinical
Khoa Vu   +8 more
doaj   +1 more source

Successful Asfotase Alfa Treatment in an Adult Dialysis Patient With Childhood-Onset Hypophosphatasia [PDF]

open access: yes, 2017
Hypophosphatasia is an inherited disease characterized by reduced alkaline phosphatase activity, extracellular accumulation of inorganic pyrophosphate, and impaired bone mineralization.
Cooper, Mark S.   +2 more
core   +1 more source

A Rare Case of Parvovirus Infection Causing Pure Red Cell Aplasia in a Kidney‐Pancreas Transplant Recipient

open access: yesNephrology, Volume 30, Issue 7, July 2025.
ABSTRACT Parvovirus B19 infection can rarely manifest with pure red cell aplasia in immunocompromised hosts. This case details a 48‐year‐old male, 11 years post kidney‐pancreas transplant who was admitted with a chronic normocytic anaemia (haemoglobin 72 g/L) after being admitted four months prior with a bleeding peptic ulcer, requiring eight units of ...
Oscar Perry   +5 more
wiley   +1 more source

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