Results 81 to 90 of about 5,123 (202)

Effect of Iron Deficiency on Short‐Term Response to Treatment in Cats With Chronic Enteropathies

open access: yesJournal of Veterinary Internal Medicine, Volume 39, Issue 3, May/June 2025.
ABSTRACT Background Iron deficiency in humans with chronic inflammatory enteropathies (CIE) is associated with active disease and anemia‐related morbidity. Objectives To compare iron deficiency prevalence in cats with CIE versus low‐grade alimentary lymphoma (LGAL) and secondarily, determine the effect of iron deficiency on short‐term clinical response
Maria C. Jugan   +3 more
wiley   +1 more source

Non‐Inferiority of Subcutaneous Efepoetin Alfa Compared to Methoxy Polyethylene Glycol‐Epoetin Beta in Stage 3 or 4 CKD Patients: Insights From a Phase 3 Trial

open access: yesNephrology, Volume 30, Issue 5, May 2025.
ABSTRACT Aim Efepoetin alfa, a novel long‐acting erythropoietin (EPO)‐hybrid Fc fusion protein, represents a promising erythropoiesis‐stimulating agent (ESA) for addressing anaemia in chronic kidney disease (CKD) patients. This Phase 3 trial was to assess the efficacy and tolerability of subcutaneous efepoetin alfa in comparison to subcutaneous methoxy
Simon D. Roger   +45 more
wiley   +1 more source

The use of darbepoetin alpha in infants

open access: yesСеченовский вестник, 2019
Among the somatic pathology in young children, the most common is anemic syndrome. Until recently, the commonest method for correction of anemia was hemotransfusion, which allows to restore normal hemoglobin quickly, but has the high risk of ...
A. V. Shchegolev   +4 more
doaj   +1 more source

Rethinking neoadjuvant chemotherapy for breast cancer [PDF]

open access: yes, 2018
Breast cancer is the most common cancer in women worldwide. In 2014, 55 000 women in the UK were given the diagnosis of breast cancer, and 11 000 died.1 Early breast cancer is traditionally treated with surgery, plus radiotherapy and adjuvant systemic ...
Alexander, E   +6 more
core   +1 more source

An Exploratory Analysis of Pharmaceutical Price Disparities and Their Implications Among Six Developed Nations [PDF]

open access: yes, 2006
In our study of 43 drugs, prescription drug prices in several wealthy nations (Australia, Canada, France, Germany, and the U.K.) were much lower than in the U.S. on average, well below relative per capita GDP. There was relatively little difference among
Elizabeth DuPre   +2 more
core  

Successful Asfotase Alfa Treatment in an Adult Dialysis Patient With Childhood-Onset Hypophosphatasia [PDF]

open access: yes, 2017
Hypophosphatasia is an inherited disease characterized by reduced alkaline phosphatase activity, extracellular accumulation of inorganic pyrophosphate, and impaired bone mineralization.
Cooper, Mark S.   +2 more
core   +1 more source

Switch from epoetin to darbepoetin alfa in hemodialysis: dose equivalence and hemoglobin stability

open access: yesInternational Journal of Nephrology and Renovascular Disease, 2014
Javier Arrieta,1 Iñigo Moina,1 José Molina,2 Isabel Gallardo,3 María Luisa Muñiz,4 Carmen Robledo,5 Oscar García,5 Fernando Vidaur,6 Rosa Inés Muñoz,3 Izaskun Iribar,7 Román Aguirre,7 Antonio Maza8 ...
Arrieta J   +11 more
doaj  

Efficacy, tolerability and safety of darbepoetin alfa injection for the treatment of anemia associated with chronic kidney disease (CKD) undergoing dialysis: a randomized, phase-III trial

open access: yesBMC Nephrology, 2019
Background Darbepoetin alfa (DA-α) is a long-acting erythropoiesis-stimulating glycoprotein which has half-life three-fold longer than that of Erythropoietin alfa (EPO). The objective of this study was to compare the efficacy and safety of DA-α injection
Shubhadeep D. Sinha   +9 more
doaj   +1 more source

Will There Be a Role for a Short-Acting Biosimilar Erythropoiesis-Stimulating Agent in US Nephrology Practice? [PDF]

open access: yes, 2019
Patent protection for pharmaceuticals in the United States is very robust and perhaps there is no greater example than epoetin alfa. Since the approval of epoetin alfa by the Food and Drug Administration (FDA) in 1989, the developer, Amgen (Thousand Oaks,
Wish, Jay B.
core   +1 more source

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