Results 81 to 90 of about 5,123 (202)
Effect of Iron Deficiency on Short‐Term Response to Treatment in Cats With Chronic Enteropathies
ABSTRACT Background Iron deficiency in humans with chronic inflammatory enteropathies (CIE) is associated with active disease and anemia‐related morbidity. Objectives To compare iron deficiency prevalence in cats with CIE versus low‐grade alimentary lymphoma (LGAL) and secondarily, determine the effect of iron deficiency on short‐term clinical response
Maria C. Jugan +3 more
wiley +1 more source
ABSTRACT Aim Efepoetin alfa, a novel long‐acting erythropoietin (EPO)‐hybrid Fc fusion protein, represents a promising erythropoiesis‐stimulating agent (ESA) for addressing anaemia in chronic kidney disease (CKD) patients. This Phase 3 trial was to assess the efficacy and tolerability of subcutaneous efepoetin alfa in comparison to subcutaneous methoxy
Simon D. Roger +45 more
wiley +1 more source
The use of darbepoetin alpha in infants
Among the somatic pathology in young children, the most common is anemic syndrome. Until recently, the commonest method for correction of anemia was hemotransfusion, which allows to restore normal hemoglobin quickly, but has the high risk of ...
A. V. Shchegolev +4 more
doaj +1 more source
Rethinking neoadjuvant chemotherapy for breast cancer [PDF]
Breast cancer is the most common cancer in women worldwide. In 2014, 55 000 women in the UK were given the diagnosis of breast cancer, and 11 000 died.1 Early breast cancer is traditionally treated with surgery, plus radiotherapy and adjuvant systemic ...
Alexander, E +6 more
core +1 more source
An Exploratory Analysis of Pharmaceutical Price Disparities and Their Implications Among Six Developed Nations [PDF]
In our study of 43 drugs, prescription drug prices in several wealthy nations (Australia, Canada, France, Germany, and the U.K.) were much lower than in the U.S. on average, well below relative per capita GDP. There was relatively little difference among
Elizabeth DuPre +2 more
core
Successful Asfotase Alfa Treatment in an Adult Dialysis Patient With Childhood-Onset Hypophosphatasia [PDF]
Hypophosphatasia is an inherited disease characterized by reduced alkaline phosphatase activity, extracellular accumulation of inorganic pyrophosphate, and impaired bone mineralization.
Cooper, Mark S. +2 more
core +1 more source
Switch from epoetin to darbepoetin alfa in hemodialysis: dose equivalence and hemoglobin stability
Javier Arrieta,1 Iñigo Moina,1 José Molina,2 Isabel Gallardo,3 María Luisa Muñiz,4 Carmen Robledo,5 Oscar García,5 Fernando Vidaur,6 Rosa Inés Muñoz,3 Izaskun Iribar,7 Román Aguirre,7 Antonio Maza8 ...
Arrieta J +11 more
doaj
Effectiveness and safety of erythropoiesis-stimulating agent use in the perioperative period [PDF]
postprin
Chee, YE +3 more
core +1 more source
Background Darbepoetin alfa (DA-α) is a long-acting erythropoiesis-stimulating glycoprotein which has half-life three-fold longer than that of Erythropoietin alfa (EPO). The objective of this study was to compare the efficacy and safety of DA-α injection
Shubhadeep D. Sinha +9 more
doaj +1 more source
Will There Be a Role for a Short-Acting Biosimilar Erythropoiesis-Stimulating Agent in US Nephrology Practice? [PDF]
Patent protection for pharmaceuticals in the United States is very robust and perhaps there is no greater example than epoetin alfa. Since the approval of epoetin alfa by the Food and Drug Administration (FDA) in 1989, the developer, Amgen (Thousand Oaks,
Wish, Jay B.
core +1 more source

