Results 1 to 10 of about 1,701 (115)
Hematin formation and pancreatitis [PDF]
Journal of Surgical Research, 1969 Abstract Production of hematin from hemoglobin in vitro is augmented by a mixture of powdered pancreatic enzymes and human pancreatic juice. Those enzymes which most affected the rate of conversion of hemoglobin to hematin were lipase, elastase, and trypsin. These same enzymes were also most active in hematin production from red cells.
Frey, Charles F. +3 more
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Photoacoustic spectroscopy of β-hematin [PDF]
Journal of Optics, 2012 Malaria affects over 200 million individuals annually, resulting in 800,000 fatalities. Current tests use blood smears and can only detect the disease when 0.1-1% of blood cells are infected. We are investigating the use of photoacoustic flowmetry to sense as few as one infected cell among 10 million or more normal blood cells, thus diagnosing ...
Edward B, Samson +6 more
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Targeting of Hematin by the Antimalarial Pyronaridine [PDF]
Antimicrobial Agents and Chemotherapy, 2006 ABSTRACT Pyronaridine, 2-methoxy-7-chloro-10[3′,5′-bis(pyrrolidinyl-1-methyl-)4′hydroxyphenyl]aminobenzyl-(b)-1,5-naphthyridine, a new Mannich base schizontocide originally developed in China and structurally related to the aminoacridine drug quinacrine, is currently undergoing clinical testing.
Saranya, Auparakkitanon +4 more
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Hematin: unique effects of hemostasis [PDF]
Blood, 1983 Hematin is clinically useful in the treatment of acute intermittent porphyria. Recently, hematin-induced coagulopathy has been reported, and a patient we treated bled during hematin therapy. On 3 separate occasions, infusions of hematin (4 mg/kg) induced thrombocytopenia, prolongation of the prothrombin time, partial thromboplastin time. Reptilase time,
R, Glueck +3 more
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HEMATIN-REQUIRING PLASMODIAL MYXOMYCETE [PDF]
Journal of Bacteriology, 1962 Daniel, John W. (University of Wisconsin, Madison), Jacqueline Kelley, and Harold P. Rusch. Hematin-requiring plasmodial myxomycete. J. Bacteriol. 84:1104-1110. 1962.-The myxomycete Physarum polycephalum, previously shown to require chick embryo extract for growth on a partially defined, soluble medium, grows as well if hematin or certain hemoproteins ...
J W, DANIEL, J, KELLEY, H P, RUSCH
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THE EFFECT OF HEMATIN ON THE CIRCULATION AND RESPIRATION [PDF]
Journal of Experimental Medicine, 1913 1. Doses of less than six milligrams of hematin and, under certain conditions, larger doses may cause a slight rise of blood pressure. 2. Large doses of hematin cause a profound and prolonged fall of blood pressure. The principal factor in this fall of blood pressure is the marked dilatation of the splanchnic vessels.
W H, Brown, A S, Loevenhart
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Hematin Enzymes of Hemophilus parainfluenzae
Journal of Biological Chemistry, 1962 A paste of washed Hemophilus parainfluenzae grown to the stationary phase with vigorous aeration appears tan to brown in color. Frozen cells are deep reddish brown and show absorption bands typical of cytochrome pigments when examined with a spectroscope.
D C, WHITE, L, SMITH
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Hematin Therapy for Acute Porphyria
Medicine, 1979 1. A therapeutic trial of intravenous hematin is presented. Eleven cases of AIP and one of VP who did not improve with conventional treatment (high carbohydrate intake) received this new agent. 2. Urinary ALA, PBG and, when possible, uroporphyrin and coproporphyrin were used to monitor the chemical response to the treatment.
J M, Lamon +3 more
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Journal of Biological ChemistryMalaria remains a significant public health challenge in equatorial regions of the world, largely owing to the parasite's emerging resistance to the recently introduced drugs of the artemisinin (ART) family. In the human body, most ART-derivative drugs are metabolized to dihydroartemisinin (DHA), which, in the parasite, after activation by heme, can ...
Azargoshasb, Hamidreza +4 more
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, 2023 Our research focused on iron deficiency in heart failure. Heart failure is a clinical syndrome which is characterized by a reduced pumping function of the heart. Many heart failure patients also have other diseases (comorbidity), of which iron deficiency is very common.
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