Results 1 to 10 of about 232,755 (310)
Proceedings of the National Academy of Sciences of the United States of America, 2022 Significance Heme availability in the cell enables the proper folding and function of enzymes, which carry heme as a cofactor. Using genome-scale modeling, we identified metabolic fluxes and genes that limit heme production.
Olena P Ishchuk +2 more
exaly +2 more sources
Analysis of putative heme ligands in the System I bacterial cytochrome c biogenesis heme transporter, CcmCD [PDF]
Microbiology SpectrumHeme is a key co-factor for biologically important proteins that are required for critical cellular functions such as oxygen transport and energy production.
Alicia N. Kreiman +5 more
doaj +2 more sources
Control of intracellular heme levels: Heme transporters and heme oxygenases
Biochimica Et Biophysica Acta - Molecular Cell Research, 2011 Heme serves as a co-factor in proteins involved in fundamental biological processes including oxidative metabolism, oxygen storage and transport, signal transduction and drug metabolism. In addition, heme is important for systemic iron homeostasis in mammals.
John G Quigley
exaly +3 more sources
Heme Synthesis and Acquisition in Bacterial Pathogens
Journal of Molecular Biology, 2016 Bacterial pathogens require the iron-containing cofactor heme to cause disease. Heme is essential to the function of hemoproteins, which are involved in energy generation by the electron transport chain, detoxification of host immune effectors, and other
Jacob E Choby, Eric P Skaar
exaly +2 more sources
NLRP12-PANoptosome activates PANoptosis and pathology in response to heme and PAMPs
Cell, 2023 SUMMARY Cytosolic innate immune sensors are critical for host defense and form complexes, such as inflammasomes and PANoptosomes, that induce inflammatory cell death.
Balamurugan Sundaram +10 more
semanticscholar +1 more source
El Perfil del Empresario de Turismo Activo y Deportes de Aventura en Extremadura
E-Motion, 2021 El turismo activo y su relación con el turismo y actividades de aventura, se ha convertido en uno de los sectores que mayor auge está experimentado en la actualidad, desarrollándose en Extremadura una importante red empresarial en relación a ello.
Jorge Rojo-Ramos +3 more
doaj +1 more source
Molecular Mechanisms of Iron and Heme Metabolism
Annual review of nutrition, 2022 An abundant metal in the human body, iron is essential for key biological pathways including oxygen transport, DNA metabolism, and mitochondrial function.
S. Dutt, I. Hamza, T. Bartnikas
semanticscholar +1 more source
Influence of Body Composition on Physical Literacy in Spanish Children
Biology, 2021 Background: Childhood obesity is a major health challenge in modern societies; therefore, prevention and management policies are needed. This study aims to establish the level of Physical Literacy (PL) in overweight and non-overweight children in ...
María Mendoza-Muñoz +6 more
doaj +1 more source
Physical exercises for preventing injuries among adult male football players: A systematic review
Journal of Sport and Health Science, 2022 Background: Football is the most practised sport in the world and is associated with the risk of injuries in the players. Some studies have been published that identify injury prevention programs, but there is no review of the full body of evidence on ...
Jorge Pérez-Gómez +3 more
doaj +1 more source
Antioxidants, 2022 The heme oxygenase (HO) enzyme system catabolizes heme to carbon monoxide (CO), ferrous iron, and biliverdin-IXα (BV), which is reduced to bilirubin-IXα (BR) by biliverdin reductase (BVR).
S. Ryter
semanticscholar +1 more source