Results 21 to 30 of about 187,269 (312)

Involvement of Small Colony Variant-Related Heme Biosynthesis Genes in Staphylococcus aureus Persister Formation in vitro

Frontiers in Microbiology, 2021
Background: Persisters are important reasons for persistent infections, and they can lead to antibiotic treatment failure in patients and consequently chronic infection.
Xuyang Wang, Weizheng Li, Wenjie Wang, Shiyong Wang, Tao Xu, Jiazhen Chen, Wenhong Zhang, Wenhong Zhang, Wenhong Zhang   +8 more
doaj   +1 more source

Biochemical and Biophysical Studies of Heme Binding Proteins from the Corynebacterium diphtheriae and Streptococcus pyogenes Heme Uptake Pathways [PDF]

, 2018
The Gram-positive pathogens Corynebacterium diphtheriae and Streptococcus pyogenes both require iron for survival. These bacteria have developed sophisticated heme uptake and transport protein machinery responsible for the import of iron into the cell ...
Draganova, Elizabeth B
core   +1 more source

Analyzing magnetic bead QuantiGene® Plex 2.0 gene expression data in high throughput mode using QGprofiler

BMC Bioinformatics, 2019
Background The QuantiGene® Plex 2.0 platform (ThermoFisher Scientific) combines bDNA with the Luminex/xMAP magnetic bead capturing technology to assess differential gene expression in a compound exposure setting.
Bie Verbist, Eva Adriaensen, Vikki Keersmaekers, Dea Putri, Marjolein Crabbe, Maarten Derks, Rytis Bagdziunas, Griet Laenen, Hans De Wolf   +8 more
doaj   +1 more source

Peroxidase activity of erythrocytes hemoglobin under action of low-frequency vibration

Біологічні студії, 2021
Background. Hemoglobin is a hemoprotein which in the presence of oxidative equivalents, such as H2O2, can act as peroxidase with a very high oxidative potential.
O. I. Dotsenko, G. V. Taradina, А. М. Mischenko   +2 more
doaj   +1 more source

Structure and Function of the Bacterial Heterodimeric ABC Transporter CydDC: Stimulation of the ATPase Activity by Thiol and Heme Compounds [PDF]

, 2014
In Escherichia coli, the biogenesis of both cytochrome bd-type quinol oxidases and periplasmic cytochromes requires the ABC- type cysteine/glutathione (GSH) transporter, CydDC.
Xie, H, Poole, Robert K,, Nyathi, Yvonne, Booth, WI, Nyathi, Y, Bullough, PA, Booth, Wesley I., Xie, Hua, Postis, Vincent; id_orcid, Poole, R. K., Tzokov, Svetomir B., Booth, W.I., Postis, Vincent, Yamashita, M., Booth, W. I., Baldwin, SA, Tzokov, S, Baldwin, Stephen A., Bullough, Per A, Postis, V, Postis, V., Yamashita, Masao, Yamashita, M, Bullough, Per A., Tzokov, Svetomir, Shepherd, M., Poole, RK, Bullough, P.A., Xie, Hao, Bullough, P. A., Poole, Robert K, Poole, R.K., Booth, Wesley I, Nyathi, Y., Tzokov, S. B., Xie, H., Baldwin, Stephen A, Baldwin, S.A., Tzokov, SB, Baldwin, S. A., Shepherd, Mark, Tzokov, S.B., Shepherd, M   +42 more
core   +1 more source

Discovering How Heme Controls Genome Function Through Heme-omics

Cell Reports, 2020
Summary: Protein ensembles control genome function by establishing, maintaining, and deconstructing cell-type-specific chromosomal landscapes. A plethora of small molecules orchestrate cellular functions and therefore may link physiological processes ...
Ruiqi Liao, Ye Zheng, Xin Liu, Yuannyu Zhang, Gretchen Seim, Nobuyuki Tanimura, Gary M. Wilson, Peiman Hematti, Joshua J. Coon, Jing Fan, Jian Xu, Sunduz Keles, Emery H. Bresnick   +12 more
doaj   +1 more source

Biochemical and Biophysical Studies of Heme Transport Proteins: HtaA, HtaB, and ChtB from the Corynebacterium diphtheriae [PDF]

, 2019
Many pathogenic bacteria require iron for their survival and virulence; in most cases hemin is the main iron source. Pathogens have developed sophisticated heme uptake mechanisms in order to maintain the homeostasis and remain as infectious agents ...
Uluisik, Rizvan C
core   +1 more source

Heme-dependent decreases in endothelial barrier resistance are TLR4-dependent. [PDF]

, 2018
Rat microvascular endothelial cell (RMVEC) monolayers were seeded in Electric Cell-substrate Impedance Sensing (ECIS) arrays as described in Methods. When monolayers reached the appropriate resistance, monolayers were treated with vehicle or heme (10 μM,
Jean-Francois Pittet (254567), Angela P. Brandon (4925758), Rakesh P. Patel (308052), Shannon W. Stephens (4925773), Judy Creighton (4925776), Marisa B. Marques (721880), Jillian R. Richter (4925779), Brant M. Wagener (586587), Jeffrey D. Kerby (4925770), Cilina A. Evans (4925767), Parker J. Hu (4925764), Charity Morgan (4925761), Jaideep Honavar (412428), Joo-Yeun Oh (704641), Randal O. Dull (829904)   +14 more
core   +1 more source

Genetic variants of the promoter of the heme oxygenase-1 gene and their influence on cardiovascular disease (The Ludwigshafen risk and cardiovascular health study) [PDF]

, 2009
Background Heme oxygenase-1 is an inducible cytoprotective enzyme which handles oxidative stress by generating anti-oxidant bilirubin and vasodilating carbon monoxide.
Hoffmann Michael M, Hoffmann, Michael Marcus, März Winfried, Boehm Bernhard O, Wellnitz Britta, Karl Winkler, Bernhard O Boehm, Bernhard R Winkelmann, März, Winfried, Winkelmann Bernhard R, Winkler Karl, Hoffmann, Michael M., Seelhorst Ursula, Ursula Seelhorst, Seelhorst, Ursula, Britta Wellnitz, Böhm, Bernhard O., Böhm, Bernhard Otto, Michael M Hoffmann, Lüblinghoff Nicola, Lüblinghoff, Nicola, Winkelmann, Bernhard Rudolf, Winfried März, Winkler, Karl, Nicola Lüblinghoff, Winkelmann, Bernhard R., Wellnitz, Britta   +26 more
core   +1 more source

Distributions of particulate Heme b in the Atlantic and Southern Oceans-Implications for electron transport in phytoplankton [PDF]

, 2013
Concentrations of heme b, the iron-containing component of b-type hemoproteins, ranged from  500). High chl a:heme b ratios resulted from relative decreases in heme b, suggesting proteins such as cytochrome b6f, the core complex of photosystem II, and ...
Nielsdottir, Maria C., Micha J. A. Rijkenberg, Achterberg, Eric P., David J. Honey, Rijkenberg, Micha J.A., Eric P. Achterberg, Maria C. Nielsdottir, Honey, David J., Rijkenberg, Micha J. A., Gledhill, Martha, Martha Gledhill   +10 more
core   +2 more sources