Results 21 to 30 of about 202,054 (300)
Microbiology Spectrum, 2022 Heme is both an essential cofactor and an abundant source of nutritional iron for the human pathogen Mycobacterium tuberculosis. While heme is required for M. tuberculosis survival and virulence, it is also potentially cytotoxic. Since M.
Rebecca K. Donegan +11 more
doaj +1 more source
Relación existente entre la ratio 2D:4D y la composición corporal en adolescentes de Extremadura
E-Motion, 2020 Introducción: La ratio 2D:4D es el cociente entre la longitud del dedo índice y anular de la mano, asociada al balance entre andrógenos y estrógenos, durante el desarrollo embrionario. Una baja proporción 2D:4D, refleja niveles más altos de testosterona
Maria Mendoza Muñoz +3 more
doaj +1 more source
Biomolecules, 2022 In patients, endometrial hyperplasia (EH) is often accompanied by abnormal uterine bleeding (AUB), which is prone to release large amounts of heme. However, the role of excess heme in the migration and infiltration of immune cells in EH complicated by ...
Lu-Yu Ruan +8 more
doaj +1 more source
Influence of Body Composition on Physical Fitness in Adolescents
Medicina, 2020 Background and objectives: Childhood obesity is one of the main public health issues facing advanced societies. The Spanish population presents 28.6% overweight or obese adolescents, and Extremadura, 22.3%.
María Mendoza-Muñoz +5 more
doaj +1 more source
Hsp90 in Human Diseases: Molecular Mechanisms to Therapeutic Approaches
Cells, 2022 The maturation of hemeprotein dictates that they incorporate heme and become active, but knowledge of this essential cellular process remains incomplete. Studies on chaperon Hsp90 has revealed that it drives functional heme maturation of inducible nitric
Mamta P. Sumi, Arnab Ghosh
doaj +1 more source
Frontiers in Microbiology, 2021 Iron is an important micronutrient that is required by bacteria to proliferate and to cause disease. Many bacterial pathogens forage iron from human hemoglobin (Hb) during infections, which contains this metal within heme (iron–protoporphyrin IX ...
Ken Ellis-Guardiola +6 more
doaj +1 more source
Characterizing the Heme Uptake Proteins HtaB and ChtB in Corynebacterium diphtheriae [PDF]
, 2020 Corynebacterium diphtheriae is a Gram-positive, pathogenic bacterium. Pathogenic bacteria require iron as a key nutrient for survival. C. diphtheriae utilizes a direct heme uptake system in which the heme binds to a receptor protein that transfers the ...
Ferrell, Brandon L
core +1 more source
Multiscale Modelling of the Electrocatalysis of Microenzymes: Insights Into the Performance of Microperoxidase at an Aqueous/Graphene Interface and Their Exploitation to Improve Performance. [PDF]
Adv Sci (Weinh)A novel multiscale MD/DFT framework to elucidate microenzyme adsorption and electron transfer is reported. This method reveals distinct configurations for microperoxidase‐11 on graphene and those best suited for electron transfer. Rate constants align with the limited experimental data, establishing this framework as a tool for optimizing microenzyme ...
Mijajlovic M +6 more
europepmc +2 more sources
Mitochondrial Impairment by MitoBloCK-6 Inhibits Liver Cancer Cell Proliferation
Frontiers in Cell and Developmental Biology, 2021 Augmenter of liver regeneration (ALR) is a critical multi-isoform protein with its longer isoform, located in the mitochondrial intermembrane space, being part of the mitochondrial disulfide relay system (DRS).
Yaschar Kabiri +12 more
doaj +1 more source
Heme iron from meat and risk of colorectal cancer: a meta-analysis and a review of the mechanisms involved [PDF]
, 2011 Red meat and processed meat intake is associated with a risk of colorectal cancer, a major cause of death in affluent countries. Epidemiological and experimental evidence supports the hypothesis that heme iron present in meat promotes colorectal cancer ...
Bastide, Nadia +6 more
core +1 more source