Results 21 to 30 of about 207,281 (307)

Pathological significance of heme oxygenase-1 as a potential tumor promoter in heme-induced colorectal carcinogenesis [PDF]

, 2023
The significance of the heme-metabolizing enzyme heme oxygenase-1 (HMOX1) in the pathogenesis of colorectal cancer (CRC) has not been fully explored. HMOX1 cytoprotection is imperative to limit oxidative stress.
Rachitha Singhabahu, Sujani M. Kodagoda Gamage, Gopalan, Vinod, Kodagoda Gamage, SM, Singhabahu, Rachitha, Singhabahu, R, Vinod Gopalan, Gopalan, V, Kodagoda Gamage, Sujani M; id_orcid   +8 more
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Peroxidase activity of erythrocytes hemoglobin under action of low-frequency vibration

Біологічні студії, 2021
Background. Hemoglobin is a hemoprotein which in the presence of oxidative equivalents, such as H2O2, can act as peroxidase with a very high oxidative potential.
O. I. Dotsenko, G. V. Taradina, А. М. Mischenko   +2 more
doaj   +1 more source

Analyzing magnetic bead QuantiGene® Plex 2.0 gene expression data in high throughput mode using QGprofiler

BMC Bioinformatics, 2019
Background The QuantiGene® Plex 2.0 platform (ThermoFisher Scientific) combines bDNA with the Luminex/xMAP magnetic bead capturing technology to assess differential gene expression in a compound exposure setting.
Bie Verbist, Eva Adriaensen, Vikki Keersmaekers, Dea Putri, Marjolein Crabbe, Maarten Derks, Rytis Bagdziunas, Griet Laenen, Hans De Wolf   +8 more
doaj   +1 more source

Structure and Function of the Bacterial Heterodimeric ABC Transporter CydDC: Stimulation of the ATPase Activity by Thiol and Heme Compounds [PDF]

, 2014
In Escherichia coli, the biogenesis of both cytochrome bd-type quinol oxidases and periplasmic cytochromes requires the ABC- type cysteine/glutathione (GSH) transporter, CydDC.
Xie, H, Poole, Robert K,, Nyathi, Yvonne, Booth, WI, Nyathi, Y, Bullough, PA, Booth, Wesley I., Xie, Hua, Postis, Vincent; id_orcid, Poole, R. K., Tzokov, Svetomir B., Booth, W.I., Postis, Vincent, Yamashita, M., Booth, W. I., Baldwin, SA, Tzokov, S, Baldwin, Stephen A., Bullough, Per A, Postis, V, Postis, V., Yamashita, Masao, Yamashita, M, Bullough, Per A., Tzokov, Svetomir, Shepherd, M., Poole, RK, Bullough, P.A., Xie, Hao, Bullough, P. A., Poole, Robert K, Poole, R.K., Booth, Wesley I, Nyathi, Y., Tzokov, S. B., Xie, H., Baldwin, Stephen A, Baldwin, S.A., Tzokov, SB, Baldwin, S. A., Shepherd, Mark, Tzokov, S.B., Shepherd, M   +42 more
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Discovering How Heme Controls Genome Function Through Heme-omics

Cell Reports, 2020
Summary: Protein ensembles control genome function by establishing, maintaining, and deconstructing cell-type-specific chromosomal landscapes. A plethora of small molecules orchestrate cellular functions and therefore may link physiological processes ...
Ruiqi Liao, Ye Zheng, Xin Liu, Yuannyu Zhang, Gretchen Seim, Nobuyuki Tanimura, Gary M. Wilson, Peiman Hematti, Joshua J. Coon, Jing Fan, Jian Xu, Sunduz Keles, Emery H. Bresnick   +12 more
doaj   +1 more source

Heme iron from meat and risk of colorectal cancer: a meta-analysis and a review of the mechanisms involved [PDF]

, 2011
Red meat and processed meat intake is associated with a risk of colorectal cancer, a major cause of death in affluent countries. Epidemiological and experimental evidence supports the hypothesis that heme iron present in meat promotes colorectal cancer ...
Bastide, Nadia, Nadia M. Bastide, Denis E. Corpet, Pierre, Fabrice, Pierre, Fabrice H.F., Corpet, Denis E., Fabrice H.F. Pierre   +6 more
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New Marker of Colon Cancer Risk Associated with Heme Intake: 1,4-Dihydroxynonane Mercapturic Acid [PDF]

, 2006
Background: Red meat consumption is associated with an increased risk of colon cancer. Animal studies show that heme, found in red meat, promotes preneoplastic lesions in the colon, probably due to the oxidative properties of this compound.
G. Gottardi, Gottardi, Gaëlle, N. Gasc, Peiro, Géraldine, S. Tache, Corpet, Denis, Cross, Amanda J., Taché, Sylviane, Bingham, Sheila A, A. J. Cross, D. E. Corpet, F. Gueraud, Gasc, Nicole, Pierre, Fabrice, Cross, Amanda J, Pierre, Fabrice H.F., Guéraud, Françoise, G. Peiro, Corpet, Denis E., S. A. Bingham, Bingham, Sheila A., F. Pierre   +21 more
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Distributions of particulate Heme b in the Atlantic and Southern Oceans - implications for electron transport in phytoplankton [PDF]

, 2013
Concentrations of heme b, the iron-containing component of b-type hemoproteins, ranged from  500). High chl a:heme b ratios resulted from relative decreases in heme b, suggesting proteins such as cytochrome b6f, the core complex of photosystem II, and ...
Nielsdottir, Maria C., Micha J. A. Rijkenberg, Achterberg, Eric P., David J. Honey, Rijkenberg, Micha J.A., Eric P. Achterberg, Maria C. Nielsdottir, Honey, David J., Gledhill, Martha, Martha Gledhill, Achterberg, E.P., Nielsdottir, M.C., Rijkenberg, M.J.A., Honey, D.J., Gledhill, M.   +14 more
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Heme-Edge Residues Modulate Signal Transduction within a Bifunctional Homo-Dimeric Sensor Protein

, 2021
Bifunctional enzymes, which contain two domains with opposing enzymatic activities, are widely distributed in bacteria, but the regulatory mechanism(s) that prevent futile cycling are still poorly understood.
Dayna C. Patterson (11768449), Jean-Paul Armache, Sayan Das (89050), James R. Kincaid, Yilin Liu, Yilin Liu (1991839), Neela H. Yennawar (1430569), Dayna C. Patterson, Emily E. Weinert (2127613), James R. Kincaid (1313820), Emily E. Weinert, Sayan Das, Neela H. Yennawar, Jean-Paul Armache (11768452)   +13 more
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HMOX1 gene promoter alleles and high HO-1 levels are associated with severe malaria in Gambian children. [PDF]

, 2012
Heme oxygenase 1 (HO-1) is an essential enzyme induced by heme and multiple stimuli associated with critical illness. In humans, polymorphisms in the HMOX1 gene promoter may influence the magnitude of HO-1 expression.
Madi Njie (177625), Walther, Brigitte, Cunnington, A., De Caul, A, Sebastian Weis, Ebonyi, A., Deininger Susanne, Aka Peter, Deininger, S., Peter Aka, Takem, Ebako N, Predazzi, Irene M, Conway David J., Predazzi, IM, Cunnington, Aubrey, Walther, Michael, Conway, DJ, Aubrey Cunnington, Njie, M., Predazzi, I. M., Weis Sebastian, Augustine Ebonyi (177659), Sarah Rowland-Jones, Walther Michael, Amambua-Ngwa, A., Sarah Rowland-Jones (74678), Scott M. Williams (177668), Robert Walton, Susanne Deininger (173844), Sirugo, G, Cunnington Aubrey, Njie, Madi, Williams Scott M., Sirugo, Giorgio, Weis, S, Augustine Ebonyi, Walton Robert, Aka, P, Aka, P., Rowland-Jones Sarah, Williams, Scott M, Williams, S. M., Ebonyi, A, Alfred Amambua-Ngwa (122336), Weis, Sebastian, De Caul, Adam, Williams, SM, Sebastian Weis (161447), Amambua-Ngwa Alfred, Takem Ebako N., Deininger, Susanne, Adam De Caul (177612), Giorgio Sirugo, Ebako N. Takem (177656), Amambua-Ngwa, A, Walton, Robert T., Ebonyi, Augustine, Alfred Amambua-Ngwa, Madi Njie, Michael Walther, Rowland-Jones, S., Giorgio Sirugo (62489), Aka, Peter, Walton, R, Njie, M, De Caul Adam, Njie Madi, Rowland-Jones, Sarah, Takem, EN, Predazzi Irene M., Takem, E. N., Robert Walton (177664), Amambua-Ngwa, Alfred, Conway, D. J., Adam De Caul, Walther, B., Weis, S., Deininger, S, Susanne Deininger, Aubrey Cunnington (177640), Conway, David J, Peter Aka (177618), Sirugo, G., Ebako N Takem, David J Conway, David J. Conway (34880), de Caul, A., Irene M. Predazzi (177634), Brigitte Walther (130764), Walther, M, Walther, M., Walther Brigitte, Walton, Robert, Cunnington, A, Scott M Williams, Irene M Predazzi, Sirugo Giorgio, Walther, B, Rowland-Jones, S, Brigitte Walther, Michael Walther (130767), Ebonyi Augustine   +101 more
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