Results 11 to 20 of about 232,755 (310)
Heme Oxygenase-1 Signaling and Redox Homeostasis in Physiopathological Conditions
Biomolecules, 2021 Heme-oxygenase is the enzyme responsible for degradation of endogenous iron protoporphyirin heme; it catalyzes the reaction’s rate-limiting step, resulting in the release of carbon monoxide (CO), ferrous ions, and biliverdin (BV), which is successively ...
Valeria Consoli +3 more
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Heme‐hemopexin: A ‘Chronosteric’ heme‐protein [PDF]
IUBMB Life, 2007 AbstractHemopexin (HPX) serves as scavenger and transporter of toxic plasma heme to the liver. HPX is formed by two four‐bladed β‐propeller domains, resembling two thick disks that lock together at a 90° angle. The heme is bound between the two β‐propeller domains in a pocket formed by the interdomain linker peptide.
ASCENZI P, FASANO, MAURO
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Biology, 2021 Functional independence in adults is conditioned by lower limb muscle strength. Thus, it seems important to assess lower limb strength using reliable and easy to reproduce measurements.
Laura Muñoz-Bermejo +6 more
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Antimicrobial Agents and Chemotherapy, 2003 A recent Letter to the Editor (R. K. Haynes, D. Monti, D. Taramelli, N. Basilico, S. Parapini, and P. Olliaro, Letter, Antimicrob. Agents Chemother. 47:1175, 2003) presented cogent evidence that artemisinin and its derivatives do not inhibit hemozoin formation in vitro.
Haynes, Richard K. +5 more
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Biology, 2021 Introduction: Fibromyalgia (FM) affects 2.40% of the Spanish population. The most widespread treatment has been the combination of patient education, pain coping strategies and exercise. With regard to patient education, there are few previous studies on
María Mendoza-Muñoz +5 more
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Blood, 2021 Sickle cell disease (SCD) is characterized by increased hemolysis which results in plasma heme overload and ultimately cardiovascular complications. Here, we hypothesized that increased heme in SCD causes upregulation of heme oxygenase 1 (Hmox1) which ...
Archita V. Menon +6 more
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Microbiology Spectrum, 2022 Heme is both an essential cofactor and an abundant source of nutritional iron for the human pathogen Mycobacterium tuberculosis. While heme is required for M. tuberculosis survival and virulence, it is also potentially cytotoxic. Since M.
Rebecca K. Donegan +11 more
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Relación existente entre la ratio 2D:4D y la composición corporal en adolescentes de Extremadura
E-Motion, 2020 Introducción: La ratio 2D:4D es el cociente entre la longitud del dedo índice y anular de la mano, asociada al balance entre andrógenos y estrógenos, durante el desarrollo embrionario. Una baja proporción 2D:4D, refleja niveles más altos de testosterona
Maria Mendoza Muñoz +3 more
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The Worst Things in Life are Free: The Role of Free Heme in Sickle Cell Disease
Frontiers in Immunology, 2021 Hemolysis is a pathological feature of several diseases of diverse etiology such as hereditary anemias, malaria, and sepsis. A major complication of hemolysis involves the release of large quantities of hemoglobin into the blood circulation and the ...
Oluwabukola T Gbotosho +2 more
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Influence of Body Composition on Physical Fitness in Adolescents
Medicina, 2020 Background and objectives: Childhood obesity is one of the main public health issues facing advanced societies. The Spanish population presents 28.6% overweight or obese adolescents, and Extremadura, 22.3%.
María Mendoza-Muñoz +5 more
doaj +1 more source