Results 11 to 20 of about 187,269 (312)

Relación existente entre la ratio 2D:4D y la composición corporal en adolescentes de Extremadura

open access: yesE-Motion, 2020
Introducción: La ratio 2D:4D es el cociente entre la longitud del dedo índice y anular de la mano, asociada al balance entre andrógenos y estrógenos, durante el desarrollo embrionario. Una baja proporción 2D:4D, refleja niveles más altos de testosterona
Maria Mendoza Muñoz   +3 more
doaj   +1 more source

Excess Heme Promotes the Migration and Infiltration of Macrophages in Endometrial Hyperplasia Complicated with Abnormal Uterine Bleeding

open access: yesBiomolecules, 2022
In patients, endometrial hyperplasia (EH) is often accompanied by abnormal uterine bleeding (AUB), which is prone to release large amounts of heme. However, the role of excess heme in the migration and infiltration of immune cells in EH complicated by ...
Lu-Yu Ruan   +8 more
doaj   +1 more source

Heme-Edge Residues Modulate Signal Transduction within a Bifunctional Homo-Dimeric Sensor Protein [PDF]

open access: yes, 2021
Bifunctional enzymes, which contain two domains with opposing enzymatic activities, are widely distributed in bacteria, but the regulatory mechanism(s) that prevent futile cycling are still poorly understood.
Dayna C. Patterson (11768449)   +13 more
core   +1 more source

Influence of Body Composition on Physical Fitness in Adolescents

open access: yesMedicina, 2020
Background and objectives: Childhood obesity is one of the main public health issues facing advanced societies. The Spanish population presents 28.6% overweight or obese adolescents, and Extremadura, 22.3%.
María Mendoza-Muñoz   +5 more
doaj   +1 more source

Hsp90 in Human Diseases: Molecular Mechanisms to Therapeutic Approaches

open access: yesCells, 2022
The maturation of hemeprotein dictates that they incorporate heme and become active, but knowledge of this essential cellular process remains incomplete. Studies on chaperon Hsp90 has revealed that it drives functional heme maturation of inducible nitric
Mamta P. Sumi, Arnab Ghosh
doaj   +1 more source

NEAr Transporter (NEAT) Domains: Unique Surface Displayed Heme Chaperones That Enable Gram-Positive Bacteria to Capture Heme-Iron From Hemoglobin

open access: yesFrontiers in Microbiology, 2021
Iron is an important micronutrient that is required by bacteria to proliferate and to cause disease. Many bacterial pathogens forage iron from human hemoglobin (Hb) during infections, which contains this metal within heme (iron–protoporphyrin IX ...
Ken Ellis-Guardiola   +6 more
doaj   +1 more source

Characterizing the Heme Uptake Proteins HtaB and ChtB in Corynebacterium diphtheriae [PDF]

open access: yes, 2020
Corynebacterium diphtheriae is a Gram-positive, pathogenic bacterium. Pathogenic bacteria require iron as a key nutrient for survival. C. diphtheriae utilizes a direct heme uptake system in which the heme binds to a receptor protein that transfers the ...
Ferrell, Brandon L
core   +2 more sources

Mitochondrial Impairment by MitoBloCK-6 Inhibits Liver Cancer Cell Proliferation

open access: yesFrontiers in Cell and Developmental Biology, 2021
Augmenter of liver regeneration (ALR) is a critical multi-isoform protein with its longer isoform, located in the mitochondrial intermembrane space, being part of the mitochondrial disulfide relay system (DRS).
Yaschar Kabiri   +12 more
doaj   +1 more source

Pathological significance of heme oxygenase-1 as a potential tumor promoter in heme-induced colorectal carcinogenesis [PDF]

open access: yes, 2023
The significance of the heme-metabolizing enzyme heme oxygenase-1 (HMOX1) in the pathogenesis of colorectal cancer (CRC) has not been fully explored. HMOX1 cytoprotection is imperative to limit oxidative stress.
Rachitha Singhabahu   +8 more
core   +1 more source

Heme iron from meat and risk of colorectal cancer: a meta-analysis and a review of the mechanisms involved [PDF]

open access: yes, 2011
Red meat and processed meat intake is associated with a risk of colorectal cancer, a major cause of death in affluent countries. Epidemiological and experimental evidence supports the hypothesis that heme iron present in meat promotes colorectal cancer ...
Bastide, Nadia   +6 more
core   +1 more source

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