Results 71 to 80 of about 5,151 (200)

The Use of Darbepoetin to Stimulate Erythropoiesis in the Treatment of Anemia of Chronic Kidney Disease in Dogs

Journal of Veterinary Internal Medicine, 2017
Background Darbepoetin alfa (darbepoetin) is an erythropoiesis‐stimulating agent used for the treatment of anemia secondary to chronic kidney disease (CKD) in dogs, but reports describing response are lacking.
E.H. Fiocchi, L.D. Cowgill, D.C. Brown, J.E. Markovich, S. Tucker, M.A. Labato, M.B. Callan   +6 more
doaj   +1 more source

The effectiveness and cost-effectiveness of erythropoiesis-stimulating agents (epoetin and darbepoetin) for treating cancer-treatment induced anaemia (including review of TA142): a systematic review and economic model [PDF]

, 2016
Background: Anaemia is a common side-effect of cancer treatments and can lead to a reduction in quality of life. Erythropoiesis-stimulating agents (ESAs) are licensed for use in conjunction with red blood cell transfusions (RBCTs) to improve cancer ...
Briscoe, Simon, Coelho, H, Crathorne, Louise, Haasova, Marcela, Hoyle, M, Huxley, N, Hyde, C, Jones-Hughes, T, Long, Linda, Medina-Lara, A, Mujica-Mota, Ruben, Napier, Mark, Snowsill, T   +12 more
core  

DETERMINATION OF DARBEPOETIN ALFA IN RABBIT PLASMA BY ELISA

Разработка и регистрация лекарственных средств, 2019
Method of quantitative determination of darbepoetin alfa in rabbit blood plasma was developed. Quantitative determination was performed by ELISA using commercially available ELISA kits for assay «Erythropoietin ELISA-Best».
M. V. Karlina, N. M. Faustova, O. N. Pozharitskaya, V. M. Kosman, V. G. Makarov, A. N. Shikov   +5 more
doaj  

RATIONAL SUPPORTIVE THERAPY FOR CHEMOTHERAPY INDUCED ANEMIA: A PHARMACO-ECONOMIC ANALYSIS OF ERYTHROPOIETIN THERAPY IN CANCER PATIENTS IN RUSSIAN FEDERATION

Онкогематология, 2018
Modern anticancer therapy due to its intensity and molecular biology orientation allows achieving higher efficiency and theoretically reducing the incidence of complications.
V. B. Larionova, I. S. Krysanov, A. V. Snegovoy, P. A. Zeinalova, V. S. Krysanova, V. Yu. Ermakova   +5 more
doaj   +1 more source

Effect of Iron Deficiency on Short‐Term Response to Treatment in Cats With Chronic Enteropathies

Journal of Veterinary Internal Medicine, Volume 39, Issue 3, May/June 2025.
ABSTRACT Background Iron deficiency in humans with chronic inflammatory enteropathies (CIE) is associated with active disease and anemia‐related morbidity. Objectives To compare iron deficiency prevalence in cats with CIE versus low‐grade alimentary lymphoma (LGAL) and secondarily, determine the effect of iron deficiency on short‐term clinical response
Maria C. Jugan, Cathy Langston, Brandon L. Plattner, Alexandra K. Ford   +3 more
wiley   +1 more source

Prognostic significance of endogenous erythropoietin in long-term outcome of patients with acute decompensated heart failure [PDF]

, 2016
Aims Although previous reports suggest that an elevated endogenous erythropoietin (EPO) level is associated with worse clinical outcomes in chronic heart failure (HF) patients, the prognostic implication of EPO in patients with acute decompensated HF ...
Anand, Anker, Asaumi, Beguin, Belonje, Belonje, Belonje, Breunig, Cazzola, Diskin, Ezekowitz, Feldschuh, George, Ghali, Grote Beverborg, Levy, Lipsic, Massie, McKee, Meer, Meer, Meer, Silverberg, Smilde, Swedberg, Takei, Teerlink, Westenbrink   +27 more
core   +1 more source

Non‐Inferiority of Subcutaneous Efepoetin Alfa Compared to Methoxy Polyethylene Glycol‐Epoetin Beta in Stage 3 or 4 CKD Patients: Insights From a Phase 3 Trial

Nephrology, Volume 30, Issue 5, May 2025.
ABSTRACT Aim Efepoetin alfa, a novel long‐acting erythropoietin (EPO)‐hybrid Fc fusion protein, represents a promising erythropoiesis‐stimulating agent (ESA) for addressing anaemia in chronic kidney disease (CKD) patients. This Phase 3 trial was to assess the efficacy and tolerability of subcutaneous efepoetin alfa in comparison to subcutaneous methoxy
Simon D. Roger, Chew Ming Wong, Phisitt Vejakama, Kuspudji Dwitanto Rahardjo, Bang‐Gee Hsu, Chang Meng Lee, I‐Wen Wu, Chin‐Chan Lee, Tunggul Diapari Situmorang, Pajaree Krisanapan, Sadanah Aqashiah Mazlan, Yu‐Sen Peng, Johanes Sarwono, Norman De Asis, Domingo Solimen, Jonny, Pornpen Sangthawan, Jin‐Bor Chen, Chia‐Liang Wang, Sungjin Chung, Agnes Jeans Villaflor, Chul Woo Yang, Wei‐Chih Kan, Yu Yang, Jenny Rubio‐Bicol, Lee Yee Yan, Sang Ho Lee, Yi‐Wen Chiu, Cheng‐Hsu Chen, Ki Young Na, Wan Hasnul Halimi Wan Hassah, Young Sun Kang, Bum‐Soon Choi, Grace Aquitania, Ki Ryang Na, Mai‐Szu Wu, Mohd Kamil Ahmad, Rey Isidto, Vincent Wu, Goh Bak Leong, Junne‐Ming Sung, Kajohnsak Noppakun, Kang‐Ju Chou, Mohamad Zaimi Abdul Wahab, Seok Joon Shin, Pringgodigdo Nugroho   +45 more
wiley   +1 more source

Pharmacokinetics‐Based Design of Subcutaneous Controlled Release Systems for Biologics

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 4, Page 668-680, April 2025.
ABSTRACT Protein therapeutics have emerged as an exceedingly promising treatment modality in recent times but are predominantly given as intravenous administration. Transitioning to subcutaneous (SC) administration of these therapies could significantly enhance patient convenience by enabling at‐home administration, thereby potentially reducing the ...
Abigail K. Grosskopf, Antonio A. Ginart, Phillip Spinosa, Vittal Shivva   +3 more
wiley   +1 more source

Initiation of darbepoetin for management of anemia in non-dialysis-dependent patients with chronic kidney disease

Saudi Journal of Kidney Diseases and Transplantation, 2016
The anemia of chronic kidney disease (CKD) is a common comorbidity seen in kidney diseases. It is also associated with increased cardiovascular morbidity and mortality and diminished quality of life.
Fatma Al Raisi, Issa Al Salmi, Pramod Kamble, Muna Al Shehri, Faissal A. M. Shaheen   +4 more
doaj  

Macrocytosis may be associated with mortality in chronic hemodialysis patients: a prospective study

BMC Nephrology, 2011
Background Macrocytosis occurs in chronic hemodialysis (CHD) patients; however, its significance is unknown. The purpose of this study was to establish the prevalence and distribution of macrocytosis, to identify its clinical associations and to ...
West Kenneth A, Soroka Steven D, Tennankore Karthik K, Kiberd Bryce A   +3 more
doaj   +1 more source