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2015
Darier’s disease (DD) is an autosomal dominant disease induced by haplo-insufficiency with variable expressivity but with complete penetrance in adults. Considerable variation in severity and in clinical manifestation was found between families. Lesions are hyperkeratotic, greasy papules, which are skin colored, yellow, or brown, that may coalesce into
Federico Bardazzi +2 more
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Darier’s disease (DD) is an autosomal dominant disease induced by haplo-insufficiency with variable expressivity but with complete penetrance in adults. Considerable variation in severity and in clinical manifestation was found between families. Lesions are hyperkeratotic, greasy papules, which are skin colored, yellow, or brown, that may coalesce into
Federico Bardazzi +2 more
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Archives of Dermatology, 1982
A 50-year-old woman, with multiple, hyperkeratotic, brown papules on the so-called seborrheic areas of the body, had had vesicles and bullae on the inner aspects of the lower extremities and the flexor aspects of the upper extremities each summer since childhood. Her father, brother, and daughter had similar papular lesions.
Michihito Niimura +2 more
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A 50-year-old woman, with multiple, hyperkeratotic, brown papules on the so-called seborrheic areas of the body, had had vesicles and bullae on the inner aspects of the lower extremities and the flexor aspects of the upper extremities each summer since childhood. Her father, brother, and daughter had similar papular lesions.
Michihito Niimura +2 more
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Archives of Dermatology, 1947
SINCE the first description by Darier 1 in 1889 more than three hundred and fifty papers have been published dealing with Darier's disease, a relatively rare condition, the cause of which, in spite of numerous investigations, remains undetermined. New knowledge of vitamin deficiency states brought promise of a fresh attack on the problem. Peck, Chargin
S. R. Brunauer +2 more
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SINCE the first description by Darier 1 in 1889 more than three hundred and fifty papers have been published dealing with Darier's disease, a relatively rare condition, the cause of which, in spite of numerous investigations, remains undetermined. New knowledge of vitamin deficiency states brought promise of a fresh attack on the problem. Peck, Chargin
S. R. Brunauer +2 more
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Management of Darier's disease
Clinical and Experimental Dermatology, 1999Darier's disease is an uncommon inherited cutaneous disease which is difficult to manage, especially in adolescence. The warty keratotic papules irritate, smell and look unsightly. Histologically, the condition is characterized by the presence of focal acantholytic dyskeratosis.
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British Journal of Dermatology, 1995
Darier's disease is an inherited disorder with well-recognized patterns of presentation. Lesions commonly affect the trunk and flexures. The diagnosis is based on the typical clinical appearance and histology showing acantholytic dyskeratosis. We report two unusual cases with prominent nodular, comedonal lesions on the face and scalp.
E.K Derrick, C.R Darley, S.M. Burge
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Darier's disease is an inherited disorder with well-recognized patterns of presentation. Lesions commonly affect the trunk and flexures. The diagnosis is based on the typical clinical appearance and histology showing acantholytic dyskeratosis. We report two unusual cases with prominent nodular, comedonal lesions on the face and scalp.
E.K Derrick, C.R Darley, S.M. Burge
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Archives of Dermatology, 1965
Fragility, splintering, fissuring of the nails, longitudinal discolorations, and subungual dyskeratoses are important diagnostic features of Darier's disease.
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Fragility, splintering, fissuring of the nails, longitudinal discolorations, and subungual dyskeratoses are important diagnostic features of Darier's disease.
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International Journal of Dermatology, 2000
A 48‐year‐old Caucasian man recounted the onset of keratotic papules on the trunk at the age of 8 years, with subsequent spread to the forearms, scalp, and forehead. His most severe disease was present on the legs. He complained of pain, itching, and noted exacerbations in the summer and with sweating.
Rajani Katta, Jon A. Reed, John E. Wolf
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A 48‐year‐old Caucasian man recounted the onset of keratotic papules on the trunk at the age of 8 years, with subsequent spread to the forearms, scalp, and forehead. His most severe disease was present on the legs. He complained of pain, itching, and noted exacerbations in the summer and with sweating.
Rajani Katta, Jon A. Reed, John E. Wolf
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2008
Darter’s disease is an autosomal dominant acantholytic disorder (OMIM # 124200) characterized by a peculiar keratinization of the epidermis, nails, and mucous membranes, resulting in a persistent eruption of keratotic papules predominantly in seborrheic areas (upper and central trunk, flexures, scalp and forehead), palmar pits and nail dystrophy ...
Carola Durán-McKinster +3 more
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Darter’s disease is an autosomal dominant acantholytic disorder (OMIM # 124200) characterized by a peculiar keratinization of the epidermis, nails, and mucous membranes, resulting in a persistent eruption of keratotic papules predominantly in seborrheic areas (upper and central trunk, flexures, scalp and forehead), palmar pits and nail dystrophy ...
Carola Durán-McKinster +3 more
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Skin research and technology, 2019
Editor, Reflectance confocal microscopy (RCM) has now been described for years in a wide variety of inflammatory skin diseases, for both diagnostic and treatment monitoring purposes, as most features reside within the epidermis and upper dermis. Moreover,
André Oliveira +3 more
semanticscholar +1 more source
Editor, Reflectance confocal microscopy (RCM) has now been described for years in a wide variety of inflammatory skin diseases, for both diagnostic and treatment monitoring purposes, as most features reside within the epidermis and upper dermis. Moreover,
André Oliveira +3 more
semanticscholar +1 more source
A Case of Acral Darier’s Disease
Dermatology, 1999A sporadic case of acral Darier’s disease in a 20-year-old woman is reported. The disease was diagnosed on the basis of clinical, histological and ultrastructural data. Only few cases of exclusively acral clinical manifestations of Darier’s disease have been described in the literature.
ROMANO C. +4 more
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