Results 41 to 50 of about 1,856 (171)

Atypical Follicular–Pigmentary Variant of Hailey–Hailey Disease: A Diagnostic Dilemma

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Hailey–Hailey disease (HHD) is a rare autosomal dominant acantholytic dermatosis characterized by recurrent erosive plaques in intertriginous areas. Atypical presentations can resemble other acantholytic disorders, making diagnosis challenging. A 38‐year‐old male presented with recurrent pruritic lesions over flexural regions, worsened by heat
Sandesh Shah, Joshana Shrestha, Rabin Baniya, Mohan Bhusal, Krishangi Pradhan, Radhika Maharjan   +5 more
wiley   +1 more source

A Case of Darier‐Roussy Sarcoidosis Mimicking Rheumatoid Nodule

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Darier‐Roussy sarcoidosis is a rare cutaneous sarcoidosis presenting with painless subcutaneous nodules and minimal systemic involvement. A 58‐year‐old Ethiopian man developed symmetrical nodules mimicking rheumatoid nodules. Histology confirmed non‐caseating granulomas.
Milion Gebrewold Abdi, Aklilu Melaku, Gelalacha Ajema Negasa, Robsan Gudeta Getachew, Selemon Gebrezgabiher Asgedom, Netsanet Azene Gebeyehu, Birhanu Kassie Reta   +6 more
wiley   +1 more source

Type one segmental Darier′s disease

Indian Journal of Dermatopathology and Diagnostic Dermatology, 2015
A 50-year-old woman presented with multiple pruritic hyperpigmented papules in a zosteriform pattern involving the abdomen and back on the left side and in a linear pattern involving the left arm and forearm of 2 years duration.
Arunprasath Palanisamy, Subramaniam Kandasamy, Sivasubramanian Vadivel, Srivenkateswaran Kothandapany   +3 more
doaj   +1 more source

Biomolecular Changes Upon Ablative Laser Therapy of the Skin: A Scoping Review

International Journal of Dermatology, Volume 65, Issue 4, Page 753-762, April 2026.
(Fractional) ablative laser therapy results in a wound healing response characterized by an inflammatory phase, dermal matrix degradation, and remodeling, collagenesis and elastogenesis. This is characterized by an increase in metalloproteinases, collagen type I, III, VII, and tropoelastin.
Marie‐Eline Pauline Henriette Debeuf, Maartje Hendrika Pieternel Rauwenhoff, Michel van Geel, Peter Martin Steijlen, Valerie Lydie Roland Marc Verstraeten   +4 more
wiley   +1 more source

Molecular Changes Induced by Carbon Dioxide Laser in Hailey‐Hailey Disease: A Potential Mechanism Underlying Treatment Efficacy

International Journal of Dermatology, Volume 65, Issue 4, Page 797-805, April 2026.
ABSTRACT Introduction Hailey‐Hailey disease (HHD) is a rare genodermatosis caused by mutations in the ATP2C1 gene that codes for SPCA1, a calcium transporter in the epidermis. HHD impairs quality of life, and no curative treatment exists. Methods To confirm the efficacy and safety of CO2 laser in HHD, we conducted a randomized, prospective, controlled ...
Javier Antoñanzas, Agustín España, Ana Gorostidi, Ana Patiño‐García, Marcos J. Araúzo‐Bravo, Daniela Gerovska, Rafael Salido‐Vallejo, Leyre Aguado‐Gil   +7 more
wiley   +1 more source

Treatment of Darier’s disease with oral magnesium: a case report

SAGE Open Medical Case Reports, 2018
Darier’s disease, an autosomal dominant genodermatosis, arises from a mutation in the ATP2A2 gene that codes for sarco/endoplasmic reticulum Ca 2+ -ATPase in the endoplasmic reticulum and is characterized by greasy keratotic papules commonly found in ...
Heidi Oi-Yee Li, Sophia Colantonio, Nordau Kanigsberg   +2 more
doaj   +1 more source

Darier-White disease: A rare genetic disorder [PDF]

JDVI (Journal of General Procedural Dermatology & Venereology Indonesia), 2018
Background: The clinical manifestation of Darier-White disease, an autosomal dominant genodermatosis, are greasy hyperkeratotic papules in seborrheic regions with nail abnormalities and mucous membrane changes due to a defective sarcoendoplasmic calcium ...
Cara Lynn Marie N. Chia, Ma Teresita G. Gabriel, Leilani R. Senador, Ciara Mae dela Cruz   +3 more
doaj   +1 more source

Encorafenib‐associated acantholytic dermatosis in collision with eccrine squamous syringometaplasia

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Francisco Meraz‐Torres, Gabi Handgretinger, Andreas Meiwes, Derya Durak, Joana Schroth, Stephan Forchhammer   +5 more
wiley   +1 more source

Dermatology 2.0: Precision medicine for inflammatory skin diseases

Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 3, Page 440-445, March 2026.
Digital immune mapping of transcriptomics profiles from inflammatory skin disease biopsies enables precise molecular diagnosis, quantification of immune modules and personalized therapy selection by matching dominant immune signatures to targeted treatments.
Jeremy Di Domizio, Antoine Girardin, Curdin Conrad, Teofila Seremet, Michel Gilliet   +4 more
wiley   +1 more source

Darier-White disease of the vulva. Presentation of a patient

Acta Médica del Centro, 2014
The Darier-White disease is an uncommon genodematoses, the transmisision of autosomal dominant, characterized by lesions involving papulokeratosic mucosal and nails; may appear papules on the vulva, specifically.
Mabel González Escudero, Amelia Betancourt Pérez, Dayren Peraza Cruz   +2 more
doaj