Results 41 to 50 of about 4,844,369 (196)
A case of segmental Darier disease treated with doxycycline monotherapy [PDF]
, 2018 Darier disease is a rare autosomal dominant disorder that results from a mutation in the gene coding for the endoplasmic reticulum membrane calcium pump Ca2+-ATPase type 2 (SERCA2), leading to compromised intercellular adhesion.
Spohn, Gina +3 more
core +1 more source
Segmental Darier’s disease, a rare disorder of keratinization: a case report
MGM Journal of Medical Sciences, 2021 We present a case of Darier disease which is a rare autosomal-dominant genodermatosis. It is clinically manifested by hyperkeratotic papules primarily affecting seborrheic areas.
Abeer M Ilyas, Ujwala Maheswari
doaj +1 more source
Dermatology Online Journal, 2008 Darier disease is an uncommon genodermatosis characterized by verrucous papules in a seborrheic distribution. The linear form of this disease is rare and could result from genetic mosaicism in this autosomal dominant disorder. We report a case of linear Darier disease that involved the right lower limb with a zosteriform distribution.
Meziane, Mariame +4 more
openaire +4 more sources
Nail Lichen Planus in Children ‐ Epidemiology, Pathogenesis, Clinical Presentation, and Treatment
JEADV Clinical Practice, EarlyView.ABSTRACT Nail lichen planus (NLP) is a chronic inflammatory disorder that, while rare in children compared to adults, represents a significant cause of pediatric nail dystrophy that requires early recognition to prevent permanent scarring and nail loss.
Francesca Pampaloni, Matilde Iorizzo
wiley +1 more source
Lasers in Surgery and Medicine, EarlyView.ABSTRACT Objectives To report the first case of Koebner phenomenon induced by picosecond laser treatment in a patient with psoriasis. We analyzed the clinical and histopathological features and discussed the possible mechanism by which the laser's photomechanical effect triggered the reaction.
Teppei Sakai, Koya Sonoda, Jun Omatsu
wiley +1 more source
Transcriptional profiling of rare acantholytic disorders suggests common mechanisms of pathogenesis
JCI Insight, 2023 Darier, Hailey-Hailey, and Grover diseases are rare acantholytic skin diseases. While these diseases have different underlying causes, they share defects in cell-cell adhesion in the epidermis and desmosome organization.
Quinn R. Roth-Carter +12 more
doaj +1 more source
Effect of Anti‐IL‐23 and Anti‐IL‐17 Therapy on Darier Disease: A Case Series
Australasian Journal of Dermatology, EarlyView.ABSTRACT Darier disease is a rare ATP2A2‐related genodermatosis for which therapeutic options remain limited, as acitretin is often constrained by toxicity and teratogenicity. In this retrospective real‐world case series of eight patients, anti‐IL‐17 therapy showed a more consistent early signal of clinical benefit than anti‐IL‐23 therapy, with greater
Maione Vincenzo +6 more
wiley +1 more source
Darier′s disease - Oral, general and histopathological features in a 7 year old child
Journal of Indian Society of Pedodontics and Preventive Dentistry, 2016 Darier′s disease, also known as keratosis follicularis, is a rare autosomal dominant genodermatosis, manifesting clinically as hyperkeratotic, firm papule that predominates in the seborrheic areas and flexures with accompanying nail abnormalities.
Sreedevi Dharman, Muthukrishnan Arvind
doaj +1 more source
Darier disease with disseminated herpes simplex virus type 2 infection [PDF]
, 2019 Darier disease (DD), also known as keratosis follicularis or Darier-White disease, is a rare autosomal dominant genodermatosis that presents as hyperkeratotic, warty papules affecting the seborrheic and intertriginous areas.
Walker, Kendra +5 more
core +1 more source
Clinical cases of Darier-White follicular dyskeratosis
Medičnì Perspektivi, 2022 Follicular dyskeratosis (Darier-White disease) is a hereditary skin disease that is extremely rare in medical practice, so errors in its diagnosis can occur.
V.Ye. Tkach +5 more
doaj +1 more source