Results 61 to 70 of about 9,158,896 (219)
Indian Journal of Paediatric Dermatology, 2023 Darier disease (DD) and acrokeratosis verruciformis of Hopf are rare autosomal dominant skin disorders. Both are caused by a single gene mutation, i.e., ATP2A2 located on chromosome 12, which is expressed in the skin and brain. However, both the diseases
Avinash Sharma +3 more
doaj +1 more source
Bacterial Skin Dysbiosis in Darier Disease
DermatologyIntroduction: Darier disease is a rare inherited disease with dominant skin manifestations including keratotic papules and plaques on sebaceous and flexural areas.
O. Reiter +9 more
semanticscholar +1 more source
Darier-White disease and Psychiatric disorders: A Case Report
European Psychiatry, 2022 Introduction Darier-White disease (DD) is a rare genodermatosis of dominant autosomic inheritance characterized by the keratinization of epidermis, nails and mucous membrane.
R.L. Esteve +3 more
doaj +1 more source
Genes, 2020 A 4-month-old female Irish Terrier presented with a well demarcated ulcerative and crusting lesion in the right ear canal. Histological analysis revealed epidermal hyperplasia with severe acantholysis affecting all suprabasal layers of the epidermis ...
M. Linek +8 more
semanticscholar +1 more source
Microbiome, 2023 Background Darier’s disease (DD) is a genodermatosis caused by mutations of the ATP2A2 gene leading to disrupted keratinocyte adhesion. Recurrent episodes of skin inflammation and infections with a typical malodour in DD indicate a role for microbial ...
Y. Amar +17 more
semanticscholar +1 more source
Grover's disease: dermoscopy, reflectance confocal microscopy, and histopathological correlation
Dermatology Practical & Conceptual, 2017 Grover’s disease is a benign condition of unknown origin characterized clinically by an erythematous papulovesicular eruption and histopathologically by intraepidermal clefting and four different patterns of acantholysis: Darier-like, pemphigus-like ...
Francesco Lacarrubba +4 more
doaj +1 more source
Increased risk of depression and anxiety in individuals with Darier disease.
British Journal of DermatologyDarier disease patients show increased risk for depression and anxiety which matches well with increased drug prescription patterns of antidepressants and anxiolytics.
P. Curman +5 more
semanticscholar +1 more source
Dermatology Online Journal, 2008 Darier disease is an uncommon genodermatosis characterized by verrucous papules in a seborrheic distribution. The linear form of this disease is rare and could result from genetic mosaicism in this autosomal dominant disorder. We report a case of linear Darier disease that involved the right lower limb with a zosteriform distribution.
Meziane, Mariame +4 more
openaire +4 more sources
The FEBS Journal, EarlyView.A BioID screen identified interacting proteins for secretory pathway calcium (Ca2+) ATPase 2C (SPCA2C) and showed new links to store‐operated Ca2+ entry. Interactions between SPCA2C and Orai1 were confirmed, along with newly identified interactions with STIM1 and CCDC47.
Petra Samardzija +9 more
wiley +1 more source
Transcriptional profiling of rare acantholytic disorders suggests common mechanisms of pathogenesis
JCI Insight, 2023 Darier, Hailey-Hailey, and Grover diseases are rare acantholytic skin diseases. While these diseases have different underlying causes, they share defects in cell-cell adhesion in the epidermis and desmosome organization.
Quinn R. Roth-Carter +12 more
doaj +1 more source