Results 61 to 70 of about 870,321 (334)

An image dust removal and enhancement method in low illumination environment based on dark-bright channel segmentation and fusion

Meitan xuebao
Due to the influence of dust, water mist and low illumination environment in coal mine, it is very difficult to accurately identify the monitoring images of belt transportation system. Aiming at the problem of poor image processing results and efficiency
Hongwei FAN, Chao ZHANG, Xiangang CAO, Jinpeng LIU, Xuhui ZHANG, Han ZHAO   +5 more
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Patch-Wise Blind Image Deblurring Via Michelson Channel Prior

IEEE Access, 2019
Motion blur exists in many computer vision tasks, including faces, texts, and low-illumination images etc. It has been proved that Dark Channel Prior (DCP) and Bright Channel Prior (BCP) can both help the image deblurring by enhancing the dark or bright ...
Guoquan Wen, Chao Min, Zeyun Jiang, Zhaozhong Yang, Xiaogang Li   +4 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Dark-Photon searches via Higgs-boson production at the LHC

, 2016
Dark photons $\bar \gamma$ mediating long-range forces in a dark sector are predicted by various new physics scenarios, and are being intensively searched for in experiments.
Biswas, Sanjoy, Gabrielli, Emidio, Heikinheimo, Matti, Mele, Barbara   +3 more
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Research on Machine Vision Image Clearness Under Fog and Haze Weather Conditions [PDF]

Jisuanji gongcheng, 2017
Aiming at restrictions of machine vision image under fog and haze weather conditions,a machine vision image defogging algorithm is proposed based on dark channel prior.It is based on atmospheric scattering model and dark channel prior principle.It uses a
CHEN Junjun,XU Bing
doaj   +1 more source

Positrons from dark matter annihilation in the galactic halo: theoretical uncertainties [PDF]

, 2008
Indirect detection signals from dark matter annihilation are studied in the positron channel. We discuss in detail the positron propagation inside the galactic medium: we present novel solutions of the diffusion and propagation equations and we focus on ...
Delahaye, T., Donato, F., Fornengo, N., Lineros, R., Salati, P.   +4 more
core   +3 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source