Results 131 to 140 of about 6,544,802 (296)
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Light thoughts on dark energy [PDF]
The physical process leading to the acceleration of the expansion of the universe is unknown. It may involve new high energy physics or extensions to gravitation.
Linder, Eric V.
core
Geometry‐driven thermal behavior in wire‐arc additive manufacturing (WAAM) influences microstructural evolution during nonequilibrium solidification of a chemically complex Fe–Cr–Nb–W–Mo–C nanocomposite system. By comparing different deposits configurations, distinct entropy–cooling rate correlations, segregation, and carbide evolution are revealed ...
Blanca Palacios +5 more
wiley +1 more source
Reconstructing and deconstructing dark energy [PDF]
The acceleration of the expansion of the universe, ascribed to a dark energy, is one of the most intriguing discoveries in science. In addition to precise, systematics controlled data, clear, robust interpretation of the observations is required to ...
Linder, Eric V.
core
Dark energy as a kinematic effect
We present a generalization of teleparallel gravity that is consistent with local spacetime kinematics regulated by the de Sitter group SO(1, 4). The mathematical structure of teleparallel gravity is shown to be given by a nonlinear Riemann-Cartan ...
Pereira, J. G. [UNESP] +3 more
core +1 more source
Testing the LSST Difference Image Analysis Pipeline Using Synthetic Source Injection Analysis
We evaluate the performance of the Legacy Survey of Space and Time Science Pipelines Difference Image Analysis (DIA) on simulated images. By adding synthetic sources to galaxies on images, we trace the recovery of injected synthetic sources to evaluate ...
S. Liu +5 more
doaj +1 more source
A unified research data management framework for heterogeneous materials data is presented. The system integrates multimodal datasets using ontologies and knowledge graphs, enabling interoperability and FAIR (findable, accessible, interoperable, reusable) data principles. By linking data across scales and workflows, it supports reproducible, Artifitial
Doaa Mohamed +6 more
wiley +1 more source
Holographic Dark Energy in Modified Barrow Cosmology. [PDF]
Sheykhi A, Hamedan MS.
europepmc +1 more source
I review the problem of dark energy focusing on the cosmological constant as the candidate and discuss its implications for the nature of gravity. Part 1 briefly overviews the currently popular `concordance cosmology' and summarises the evidence for dark energy.
openaire +2 more sources

