Results 101 to 110 of about 685,566 (247)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Annihilation vs. Decay: Constraining dark matter properties from a gamma-ray detection

, 2010
Most proposed dark matter candidates are stable and are produced thermally in the early Universe. However, there is also the possibility of unstable (but long-lived) dark matter, produced thermally or otherwise.
A. Ibarra, A.A. Abdo ., A.M. Green, A.M. Green, A.Z. Bonanos, B.S. Hensley, C. Boehm, C.-L. Shan, C.-L. Shan, C.-R. Chen, E. Hayashi, E. Nardi, E.A. Baltz ., F. Halzen, F.J. Sanchez-Salcedo, Fermi-LAT collaboration, G. Bertone, G. Bertone, G. Wikstrom, G.D. Martinez, HESS collaboration, I. Cholis, I.Z. Rothstein, IceCube collaboration, J. Diemand, J. Diemand, J. Einasto, J. Mardon, J. Penarrubia, J.D. Simon, J.F. Navarro, J.F. Navarro, Jennifer M Siegal-Gaskins, K.N. Abazajian, L. Bergstrom, L. Bergstrom, L. Pieri, L. Zhang, L.E. Strigari ., L.E. Strigari ., M. Cirelli, M. Cirelli, M. Drees, M. Kamionkowski, M. Kuhlen, M. Oguri, M. Papucci, M. Pohl, M.G. Walker ., MAGIC collaboration, MAGIC collaboration, MAGIC collaboration, N. Bernal, N. Bernal, N.F. Martin, P. Madau, P. Scott ., R. Cen, R. Cen, R.M. Wagner ., S. De Lope Amigo, S. Kazantzidis ., S. Lombardi ., S. Profumo, Sergio Palomares-Ruiz, T. Bringmann, T. Bringmann, T. Sjöstrand, T.E. Jeltema, T.E. Jeltema, VERITAS collaboration, WMAP collaboration, X.-G. He, Y.-T. Chou   +73 more
core   +1 more source

The GAPS experiment: Low-energy antinuclei measurements for dark matter searches

EPJ Web of Conferences, 2023
GAPS (General Anti-Particle Spectrometer) is a balloon-borne experiment designed to measure low-energy (<0.25 GeV/n) cosmic antinuclei (i.e., antiprotons, antideuterons, and antihelium nuclei) as a signature of dark matter annihilation or decay.
openaire   +2 more sources

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Supersymmetry with Light Dark Matter confronting the recent CDMS and LHC Results

, 2013
We revisit MSSM scenarios with light neutralino as a dark matter candidate in view of the latest LHC and dark matter direct and indirect detection experiments. We show that scenarios with a very light neutralino (~ 10 GeV) and a scalar bottom quark close
Arbey, Alexandre, Battaglia, Marco, Mahmoudi, Farvah   +2 more
core   +3 more sources

Unlocking the Power of Quercetin‐Encapsulated Mesoporous Bioactive Glass Nanoparticles: A Multifunctional Approach to Bone Regeneration

Advanced Engineering Materials, EarlyView.
Mesoporous bioactive glass nanoparticles (MBGNs) are investigated for bone regeneration given their remarkable structural and functional properties. MBGNs are functionalized with Mn and Cu and incorporated with quercetin, a natural flavonoid exhibiting antioxidant, anti‐inflammatory, and antimicrobial properties.
Giovanni Lo Bello, Qaisar Nawaz, Pier Francesco Ferrari, Laura Pastorino, Roberto Raiteri, Aldo R. Boccaccini   +5 more
wiley   +1 more source

Interaction between Molten Al‐Killed Mn–B Steel and Carbon‐Bonded MgO Refractories Based on Recyclates

Advanced Engineering Materials, EarlyView.
High‐temperature interactions between low‐sulfur Al‐killed Mn–B steel and MgO–C refractories (0 and 50 wt% recyclates) are studied via finger immersion tests (1600 °C). Surface‐active elements influence infiltration. MgO/CaS layer forms, along with spinel and calcium silicate.
Matheus Roberto Bellé, Lukas Neubert, Anton Yehorov, Till M. J. Stadtmüller, Christos G. Aneziris, Olena Volkova   +5 more
wiley   +1 more source

Bimetallic (NiFe) and Trimetallic (NiFeCr) Nanoalloys from Metal Oxides Using a Microwave Hydrogen Plasma

Advanced Engineering Materials, EarlyView.
Bimetallic (NiFe) and trimetallic (NiFeCr) nanoalloys (NAs) are synthesized using corresponding oxide mixtures using microwave hydrogen plasma within a few milliseconds. The process simultaneously 1) reduces metal oxides to metals; 2) downsizes the particles from micrometers to nanometers; and 3) blends the metals to form NAs.
Sachin Kumar, Mohammad Kazemi, Zichang Xiong, Thomas Cameron, Julian Held, Uwe Kortshagen   +5 more
wiley   +1 more source

An explanation of one-loop induced h→μτ decay

Physics Letters B, 2016
We discuss a possibility to explain the excess of h→μτ at one-loop level. We introduce three generations of vector-like lepton doublet L′ and two singlet scalars S1,2 which are odd under Z2, while all the standard model fields are even under this ...
Seungwon Baek, Takaaki Nomura, Hiroshi Okada   +2 more
doaj   +1 more source