Results 91 to 100 of about 738,435 (332)
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Effects of f(R) Dark Energy on Dissipative Anisotropic Collapsing Fluid
, 2010 The purpose of this paper is to study the effects of dark energy on dynamics of the collapsing fluid within the framework of metric f(R) gravity. The fluid distribution is assumed to be locally anisotropic and undergoing dissipation in the form of heat ...
Kausar, H. Rizwana, Sharif, M.
core +1 more source
Bounce universe induced by an inhomogeneous dark fluid coupled with dark matter [PDF]
Modern Physics Letters A, 2014 We investigate cosmological models with a linear inhomogeneous time-dependent equation-of-state (EoS) for the dark energy, coupled with dark matter, leading to a bounce cosmology. Equivalent descriptions in terms of the EoS parameters for an exponential, a power-law, or a double exponential form of the scale factor a is obtained.
Brevik, I. +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
The Equivalence between Different Dark (Matter) Energy Scenarios
, 2004 We have shown that the phenomenological models with a cosmological constant of the type $\Lambda=\beta(\frac{\ddot R}{R})$ and $\Lambda=3\alpha H^2$, where $R$ is the scale factor of the universe and $H$ is the Hubble constant, are equivalent to a ...
Arbab, Arbab I.
core +2 more sources
Holographic dark energy in curved spacetime for interacting fluids [PDF]
, 2021 A. Bolaños +3 more
openalex +1 more source
, 2022 The cosmological gauge field (CGF) is a classical solution of SU(2)-weak gauge theory oscillating rapidly in time. It is the dark matter driving the CGF cosmology. A general, local, mathematically natural construction of the CGF is given here. The macroscopic properties are derived. The CGF is an irrotational perfect fluid.
openaire +2 more sources
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Dynamical system analysis of a three fluid cosmological model: an invariant manifold approach
European Physical Journal C: Particles and Fields, 2019 The present paper considers a three-fluid cosmological model consisting of noninteracting dark matter, dark energy and baryonic matter in the background of the Friedman–Robertson–Walker–Lemaître flat spacetime.
Subhajyoti Pal, Subenoy Chakraborty
doaj +1 more source
Dark-Soliton Molecules in an Exciton-Polariton Superfluid
Physical Review X, 2020 The general theory of dark solitons relies on repulsive interactions and, therefore, predicts the impossibility to form dark-soliton bound states. One important exception to this prediction is the observation of bound solitons in nonlocal nonlinear media.
Anne Maître +7 more
doaj +1 more source