Results 71 to 80 of about 738,678 (282)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

A new pressure-parametrization unified dark fluid model

European Physical Journal C: Particles and Fields, 2017
We propose a new pressure-parametrization model to explain the accelerated expansion of the late-time Universe by considering the baryon matter and dark contents (dark matter and dark energy) as a unified dark fluid. To realize this model more physically,
Deng Wang, Yang-Jie Yan, Xin-He Meng
doaj   +1 more source

Dynamics and epicyclic motions of particles around the Schwarzschild–de Sitter black hole in perfect fluid dark matter

European Physical Journal C: Particles and Fields, 2021
In this paper, we investigate circular orbits for test particles around the Schwarzschild–de Sitter (dS) black hole surrounded by perfect fluid dark matter.
Javlon Rayimbaev, Sanjar Shaymatov, Mubasher Jamil   +2 more
doaj   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Fluids of Vortices And Dark Matter

, 2000
REVTeX, 9 PostScript figures with ...
Bonjour, Filipe, Letelier, P. S.
openaire   +3 more sources

VISCOUS DARK FLUID UNIVERSE: A UNIFIED MODEL OF THE DARK SECTOR? [PDF]

International Journal of Modern Physics: Conference Series, 2011
The Universe is modeled as consisting of pressureless baryonic matter and a bulk viscous fluid which is supposed to represent a unified description of the dark sector. In the homogeneous and isotropic background the total energy density of this mixture behaves as a generalized Chaplygin gas.
Zimdahl, W., Velten, H. E. S., Hipólito-Ricaldi, W. S.   +2 more
openaire   +2 more sources

A Relativistic Compact Stellar Model of Anisotropic Quark Matter Mixed with Dark Energy

Advances in High Energy Physics, 2021
The possibility of strange stars mixed with dark energy to be one of the candidates for dark energy stars is the main issue of the present study. Our investigation shows that quark matter atcs as dark energy after a certain yet unknown critical condition
Theophanes Grammenos, Farook Rahaman, Saibal Ray, Debabrata Deb, Sourav Roy Chowdhury   +4 more
doaj   +1 more source

Could pressureless dark matter have pressure?

, 2012
A two-fluid dark matter model, in which dark matter is represented as a two-component fluid thermodynamic system, without interaction between the constituent particles of different species, and with each distinct component having a different four ...
Albuquerque, Bernal, Bertolami, Bharadwaj, Binney, Boehmer, Boehmer, Boehmer, Boriello, Borowiec, Briscese, Burkert, Capozziello, Capozziello, Chavanis, Chavanis, Francisco S.N. Lobo, Fuchs, Giannios, Haager, Haager, Harko, Harko, Harko, Harko, Hernández, Herrera, Hogan, Klypin, Letelier, Letelier, Madsen, Martins, Matos, Mielke, Navarro, Navarro, Nucamendi, Ostriker, Overduin, Padmanabhan, Peebles, Persic, Rubin, Saxton, Su, Tiberiu Harko   +46 more
core   +1 more source

DARK FLUID: A UNIFIED FRAMEWORK FOR MODIFIED NEWTONIAN DYNAMICS, DARK MATTER, AND DARK ENERGY [PDF]

The Astrophysical Journal, 2010
Empirical theories of dark matter (DM) like modified Newtonian dynamics (MOND) gravity and of dark energy (DE) like f(R) gravity were motivated by astronomical data. But could these theories be branches rooted from a more general and hence generic framework?
Zhao, H., Li, B.
openaire   +2 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source