Results 111 to 120 of about 738,435 (332)

Thermodynamic aspects of dark energy fluids [PDF]

open access: yesPhysical Review D, 2015
7 pages, 1 figure, 1 table. This an updated version of the article originally named "Is this the end of dark energy?"
Barboza Jr., Edésio M.   +3 more
openaire   +2 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Insights on Dark Matter from Hydrogen during Cosmic Dawn

open access: yes, 2018
The origin and composition of the cosmological dark matter remain a mystery. However, upcoming 21-cm measurements during cosmic dawn, the period of the first stellar formation, can provide new clues on the nature of dark matter.
Loeb, Abraham, Muñoz, Julian B.
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Some remarks on the observational constraints on the self-interacting scalar field model for dark energy

open access: yes, 2009
The dark energy component of the cosmic budget is represented by a self-interacting scalar field. The violation of the null energy condition is allowed. Hence, such component can also represent a phantom fluid. The model is tested using supernova type Ia
Fabris, Julio C., Jardim, Deborah F.
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Universal relation involving fundamental modes in two-fluid dark matter admixed neutron stars

open access: yesEuropean Physical Journal C: Particles and Fields
We systematically investigate the fundamental oscillation frequencies of dark matter admixed neutron stars, focusing on models with self-interacting fermionic dark matter that couples to normal matter solely through gravity.
Hajime Sotani, Ankit Kumar
doaj   +1 more source

Dark Energy and Spacetime Symmetry

open access: yesUniverse, 2017
The Petrov classification of stress-energy tensors provides a model-independent definition of a vacuum by the algebraic structure of its stress-energy tensor and implies the existence of vacua whose symmetry is reduced as compared with the maximally ...
Irina Dymnikova
doaj   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

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