Results 141 to 150 of about 4,173,231 (371)

The evolution of large-scale structure in a universe dominated by cold dark matter

open access: yes, 1985
The results of numerical simulations of nonlinear gravitational clustering in universes dominated by weakly interacting, 'cold' dark matter are presented.
M. Davis   +3 more
semanticscholar   +1 more source

Dark Future for Dark Matter

open access: yesJournal of Modern Physics, 2020
The prevailing cosmological constant and cold dark matter (LCDM) cosmic concordance model accounts for the radial expansion of the universe after the Big Bang. The model appears to be authoritative because it is based on the Einstein gravitational field equation.
Eckhardt, D.H., Garrido Pestaña, J.L.
openaire   +5 more sources

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

Insights into the phylogeny and coding potential of microbial dark matter

open access: yesNature, 2013
Genome sequencing enhances our understanding of the biological world by providing blueprints for the evolutionary and functional diversity that shapes the biosphere.
Christian Rinke   +21 more
semanticscholar   +1 more source

Dark branes for dark matter

open access: yesPhysical Review D
We propose a setup for the origin of dark matter based on spacetime with a warped extra dimension and three branes: the Planck brane, the TeV brane, at a (few) TeV scale ρT, and a dark brane, at a (sub-)GeV scale ρ1≲100  GeV≪ρT. The Standard Model (SM) is localized in the TeV brane, thus solving the Higgs hierarchy problem, while the dark matter χ, a ...
Fotis Koutroulis   +3 more
openaire   +2 more sources

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

EGFR‐STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1‐positive prostate cancer

open access: yesMolecular Oncology, EarlyView.
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva   +5 more
wiley   +1 more source

Effect of the pion field on the distributions of pressure and shear in the proton

open access: yesPhysics Letters B, 2022
In light of recent experimental progress in determining the pressure and shear distributions in the proton, these quantities are calculated in a model with confined quarks supplemented by the pion field required by chiral symmetry.
Shiryo Owa, A.W. Thomas, X.G. Wang
doaj  

Implications of Two-component Dark Matter Induced by Forbidden Channels and Thermal Freeze-out

open access: yes, 2017
We consider a model of two-component dark matter based on a hidden $U(1)_D$ symmetry, in which relic densities of the dark matter are determined by forbidden channels and thermal freeze-out.
Aoki, Mayumi, Toma, Takashi
core   +1 more source

Dark Matter 2014 [PDF]

open access: yesEPJ Web of Conferences, 2015
This article gives an overview on the status of experimental searches for dark matter at the end of 2014. The main focus is on direct searches for weakly interacting massive particles (WIMPs) using underground-based low-background detectors, especially on the new results published in 2014.
openaire   +5 more sources

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