Results 121 to 130 of about 1,630,167 (297)

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Upconversion of phonon modes into microwave photons in a lithium niobate bulk acoustic wave resonator coupled to a microwave cavity

open access: yesAPL Photonics
The coupling between acoustic vibrations in a lithium niobate bulk acoustic wave resonator and microwave photons of a re-entrant microwave cavity was investigated at a temperature close to 4 K.
S. Parashar   +5 more
doaj   +1 more source

Probing dark matter

open access: yesNature, 1995
Recent novel observations have probed the baryonic fraction of the galactic dark matter that has eluded astronomers for decades. Late in 1993, the MACHO and EROS collaborations announced in this journal the detection of transient and achromatic brightenings of a handful of stars in the Large Magellanic Cloud that are best interpreted as gravitational ...
Burrows, Adam, Liebert, Jim
openaire   +2 more sources

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

The Carrier Wave Principle

open access: yesInternational Journal of Communication, 2019
In this article, we propose a new theoretical premise called the “carrier wave principle.” It holds that there is no fixed limit to the amount and variety of knowledge that may be produced from a given cultural artifact.
Aram Sinnreich, Jesse Gilbert
doaj  

Demonstration of scissor-cross ionization injection in laser wakefield accelerators

open access: yesCommunications Physics
Laser wakefield acceleration (LWFA) holds great potential in the exploration of the next-generation accelerators and future colliders, in which the injection mechanism plays a crucial role as it directly affects the characteristics of electron ...
Siyu Chen   +18 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Off-Axis Color Characteristics of Binary Neutron Star Merger Events: Applications for Space Multi-Band Variable Object Monitor and James Webb Space Telescope

open access: yesUniverse
With advancements in gravitational wave detection technology, an increasing number of binary neutron star (BNS) merger events are expected to be detected.
Hongyu Gong, Daming Wei, Zhiping Jin
doaj   +1 more source

Supersymmetric dark matter

open access: yesPhysics Reports, 1996
The complete postscript file is available at ftp://ftp.npac.syr.edu/pub/users/jungman/susyreview/susyreview.ps.Z The TeX source and figures (plain TeX; macros included) are at ftp://ftp.npac.syr.edu/pub/users/jungman/susyreview/susyreview.tar.Z Full paper NOT submitted to lanl archive: table of contents only.
Jungman, G.   +5 more
openaire   +2 more sources

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