Results 161 to 170 of about 4,173,231 (371)

Comprehensive asymmetric dark matter model

, 2018
Asymmetric dark matter (ADM) is motivated by the similar cosmological mass densities measured for ordinary and dark matter. We present a comprehensive theory for ADM that addresses the mass density similarity, going beyond the usual ADM explanations of ...
Lonsdale, Stephen J., Volkas, Raymond R.
core   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Model-independent approach for incorporating interference effects in collider searches for new resonances

European Physical Journal C: Particles and Fields, 2020
The presence of large-mass resonances in the data collected at the Large Hadron Collider would provide direct evidence of physics beyond the Standard Model.
Stefano Frixione, Lydia Roos, Edmund Ting, Eleni Vryonidou, Martin White, Anthony G. Williams   +5 more
doaj   +1 more source

Bouncing dark matter

Physical Review D
We present a novel mechanism for thermal dark matter production, characterized by a “bounce”: the dark matter equilibrium distribution transitions from the canonical exponentially falling abundance to an exponentially rising one, resulting in an enhancement of the freeze-out abundance by many orders of magnitude.
Lucas Puetter, Joshua T. Ruderman, Ennio Salvioni, Bibhushan Shakya   +3 more
openaire   +4 more sources

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

Molecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban, Shivakumar Keerthikumar, Ashlee Clark, Hong Wang, Belinda Phipson, Andrew Bakshi, Andrew Ryan, Heather Thorne, Renea A. Taylor, Mitchell G. Lawrence, Gail P. Risbridger, Roxanne Toivanen, David L. Goode   +12 more
wiley   +1 more source

Dark matter and the early Universe: A review [PDF]

, 2021
A. Arbey, F. Mahmoudi
semanticscholar   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

II. Interstellar Matter and Young Stars: The distribution of Emission-line Stars in the Taurus Dark Nebulae [PDF]

, 1966
G. H. Herbig, M. Peimbert
openalex   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Formation of galaxies and large-scale structure with cold dark matter [PDF]

, 1984
George R. Blumenthal, S. M. Faber, Joel R. Primack, M. J. Rees   +3 more
openalex   +1 more source