Results 101 to 110 of about 2,177 (259)

Integrated Single‐Nucleus Multi‐Omics Atlases Reveal Lineage Plasticity and Regulatory Networks of Luminal Epithelial Cells During Mammary Gland Lactation and Involution

Advanced Science, EarlyView.
This study integrates single‐cell multi‐omics, spatial transcriptomics, and cross‐species comparative analyses to systematically characterize the cellular composition and differentiation trajectories of goat mammary epithelial cells, along with the gene regulatory networks and intercellular communication mechanisms governing these trajectories, thereby
Xiaoru Yan, Xiaoyu Mi, Guanghui Tan, Xinmei Li, Zhenliang Zhu, Zhenyu Wei, Huimei Fan, Yamei Wu, Tao Shi, Lingzhao Fang, Yuanpeng Gao, Yu Wang, Jun Liu   +12 more
wiley   +1 more source

An accurate solar axions ray-tracing response of BabyIAXO

Journal of High Energy Physics
BabyIAXO is the intermediate stage of the International Axion Observatory (IAXO) to be hosted at DESY. Its primary goal is the detection of solar axions following the axion helioscope technique. Axions are converted into photons in a large magnet that is
IAXO collaboration, S. Ahyoune, K. Altenmüller, I. Antolín, S. Basso, P. Brun, F. R. Candón, J. F. Castel, S. Cebrián, D. Chouhan, R. Della Ceca, M. Cervera-Cortés, V. Chernov, M. M. Civitani, C. Cogollos, E. Costa, V. Cotroneo, T. Dafní, A. Derbin, K. Desch, M. C. Díaz-Martín, A. Díaz-Morcillo, D. Díez-Ibáñez, C. Diez Pardos, M. Dinter, B. Döbrich, I. Drachnev, A. Dudarev, A. Ezquerro, S. Fabiani, E. Ferrer-Ribas, F. Finelli, I. Fleck, J. Galán, G. Galanti, M. Galaverni, J. A. García, J. M. García-Barceló, L. Gastaldo, M. Giannotti, A. Giganon, C. Goblin, N. Goyal, Y. Gu, L. Hagge, L. Helary, D. Hengstler, D. Heuchel, S. Hoof, R. Iglesias-Marzoa, F. J. Iguaz, C. Iñiguez, I. G. Irastorza, K. Jakovčić, D. Käfer, J. Kaminski, S. Karstensen, M. Law, A. Lindner, M. Loidl, C. Loiseau, G. López-Alegre, A. Lozano-Guerrero, B. Lubsandorzhiev, G. Luzón, I. Manthos, C. Margalejo, A. Marín-Franch, J. Marqués, F. Marutzky, C. Menneglier, M. Mentink, S. Mertens, J. Miralda-Escudé, H. Mirallas, F. Muleri, V. Muratova, J. R. Navarro-Madrid, X. F. Navick, K. Nikolopoulos, A. Notari, A. Nozik, L. Obis, A. Ortiz-de-Solórzano, T. O’Shea, J. von Oy, G. Pareschi, T. Papaevangelou, G. Pareschi, K. Perez, O. Pérez, E. Picatoste, M. J. Pivovaroff, J. Porrón, M. J. Puyuelo, A. Quintana, J. Redondo, D. Reuther, A. Ringwald, M. Rodrigues, A. Rubini, S. Rueda-Teruel, F. Rueda-Teruel, E. Ruiz-Chóliz, J. Ruz, J. Schaffran, T. Schiffer, S. Schmidt, U. Schneekloth, L. Schönfeld, M. Schott, L. Segui, U. R. Singh, P. Soffitta, D. Spiga, M. Stern, O. Straniero, F. Tavecchio, E. Unzhakov, N. A. Ushakov, G. Vecchi, J. K. Vogel, D. M. Voronin, R. Ward, A. Weltman, C. Wiesinger, R. Wolf, A. Yanes-Díaz, Y. Yu   +128 more
doaj   +1 more source

Electroluminescence TPCs at the thermal diffusion limit

Journal of High Energy Physics, 2019
The NEXT experiment aims at searching for the hypothetical neutrinoless double-beta decay from the 136Xe isotope using a high-purity xenon TPC. Efficient discrimination of the events through pattern recognition of the topology of primary ionisation ...
The NEXT collaboration, C. A. O. Henriques, C. M. B. Monteiro, D. González-Díaz, C. D. R Azevedo, E. D. C. Freitas, R. D. P. Mano, M. R. Jorge, A. F. M. Fernandes, J. J. Gómez-Cadenas, L. M. P. Fernandes, C. Adams, V. Álvarez, L. Arazi, K. Bailey, F. Ballester, J. M. Benlloch-Rodríguez, F. I. G. M. Borges, A. Botas, S. Cárcel, J. V. Carrión, S. Cebrián, C. A. N. Conde, J. Díaz, M. Diesburg, J. Escada, R. Esteve, R. Felkai, P. Ferrario, A. L. Ferreira, J. Generowicz, A. Goldschmidt, R. Guenette, R. M. Gutiérrez, K. Hafidi, J. Hauptman, A. I. Hernandez, J. A. Hernando Morata, V. Herrero, S. Johnston, B. J. P. Jones, M. Kekic, L. Labarga, A. Laing, P. Lebrun, N. López-March, M. Losada, J. Martín-Albo, A. Martínez, G. Martínez-Lema, A. McDonald, F. Monrabal, F. J. Mora, J. Muñoz Vidal, M. Musti, M. Nebot-Guinot, P. Novella, D. R. Nygren, B. Palmeiro, A. Para, J. Pérez, F. Psihas, M. Querol, J. Renner, J. Repond, S. Riordan, L. Ripoll, J. Rodríguez, L. Rogers, C. Romo-Luque, F. P. Santos, J. M. F. dos Santos, A. Simón, C. Sofka, M. Sorel, T. Stiegler, J. F. Toledo, J. Torrent, J. F. C. A. Veloso, R. Webb, J. T. White, N. Yahlali   +81 more
doaj   +1 more source

Aberrant GRP78 Phase Transition Sustains Endothelial IRE1α Signaling and Drives Blood–Brain Barrier Failure in Cerebral Amyloid Angiopathy

Advanced Science, EarlyView.
Vascular Aβ40 corrupts GRP78 phase behavior in brain endothelial cells, sustaining IRE1α–TRAF2–JNK signaling and driving apoptosis, tight junction loss, and blood–brain barrier failure in cerebral amyloid angiopathy. Pharmacological IRE1α inhibition restores vascular integrity, reduces leakage, and improves functional outcomes, revealing a targetable ...
Honglin Zheng, Qiang Li, Haiyang Luo, Yapei Yuan, Na Zhang, Yongting Lu, Suying Duan, Jieshi Zhong, Hang Zhang, Chenyang Liu, Yaochong Zhang, Wenzhuo Zhao, Yaxuan Song, Tuo Wang, Si Yan, Yapeng Li, Han Liu, Yuan Gao, Zongping Xia, Yuming Xu   +19 more
wiley   +1 more source

Radon-induced surface contaminations in neutrinoless double beta decay and dark matter experiments

Pas de résumé en ...
openaire   +3 more sources

Enhanced detectability of axion’s electromagnetic response with a RF-excited magnetic field in cavity

Journal of High Energy Physics
Haloscope is one of the typical installations to detect the electromagnetic responses (EMRs) of axion field in radio-frequency (RF) and microwave bands.
Li Gao, Hao Zheng, Xianing Feng, Suirong He, Lingbo Zhao, Qingquan Jiang, Lianfu Wei   +6 more
doaj   +1 more source

Exploring X-ray lines as scotogenic signals

Physics Letters B, 2014
We consider some implications of X-ray lines from certain astronomical objects as potential effects of dark matter decay in the context of the scotogenic model, where neutrinos acquire mass radiatively via one-loop interactions with dark matter.
Gaber Faisel, Shu-Yu Ho, Jusak Tandean
doaj   +1 more source

Multifunctional Manganese Oxide Nanocomposite Hydrogel With Synergistic Reactive Oxygen Species‐Scavenging, Oxygen‐Generating, Immunomodulatory, and Photothermal Antimicrobial Activities for Enhanced Diabetic Wound Healing

Advanced Science, EarlyView.
CFP/PC@MnO2 hydrogel integrates ROS scavenging, oxygen delivery, oxidative stress reduction, immunomodulation, and photothermal antibacterial properties. The incorporation of PC@MnO2 NPs endows the hydrogel with multiple functional advantages tailored to the pathological microenvironment of diabetic wounds, including efficient ROS clearance, mitigation
Zhi Xu, Xiaodong Luo, Jingxian Wu, Chaoyang Huang, Zhuoying Yang, Yixiang HePeng, Bosong Zhou, Xiang Li, Ruiyuan Liu, Xu Wu   +9 more
wiley   +1 more source

AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing

Advanced Science, EarlyView.
A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li, Haojie Fu, Zhe Wang, Xuanzhou Chen, Ruhong Zhang, Xudong Wang, Louis D. Zhang, Xiang Li, Datao Li   +8 more
wiley   +1 more source

Li-containing scintillating bolometers for low background physics

EPJ Web of Conferences, 2014
We present the performances of Li-based compounds used as scintillating bolometer for rare decay studies such as double-beta decay and direct dark matter investigations.
Pattavina L.
doaj   +1 more source