Results 261 to 270 of about 22,137 (292)

Identification of MEF2A, MEF2C, and MEF2D interactomes in basal and Fsk‐stimulated mouse MA‐10 Leydig cells

open access: yesAndrology, EarlyView.
Abstract Background Myocyte enhancer factor 2 transcription factors regulate essential transcriptional programs in various cell types. The activity of myocyte enhancer factor 2 factors is modulated through interactions with cofactors, chromatin remodelers, and other regulatory proteins, which are dependent on cell context and physiological state.
Karine de Mattos   +4 more
wiley   +1 more source

Macau as Method: Recombinant Urbanism in Post‐Socialist China

open access: yesAsia Pacific Viewpoint, EarlyView.
ABSTRACT In ‘Asia as Method’, Chen Kuan‐Hsing argues for the value of an indigenous inter‐Asian approach to analysing the effects of European imperialism on the countries and citizens of Asia. This article mobilises both Chen's inter‐Asian referencing strategy and the city‐state of Macau to explore Macau's role in China's engagements with global ...
Tim Simpson
wiley   +1 more source

‘Clinging Together Against the Dark’: A Pragmatist Reading of Sustainability Conversations

open access: yesBusiness Ethics, the Environment &Responsibility, EarlyView.
ABSTRACT In this paper, we present a typology of managers' interpretations of sustainability as ‘narrative fields’ derived from a qualitative multi‐site study and offer a Pragmatist reading of the results. Pragmatism is grounded in an ethic of meliorism, the belief in the possibility of gradually improving the world through human effort and ...
Barry A. Colbert, Elizabeth C. Kurucz
wiley   +1 more source

Cave Palaeolithic of the Ural Mountains – a review

open access: yesBoreas, EarlyView.
The Ural Mountains are of fundamental importance for studying early human migrations along the geographical limits between Europe and Asia. Geological processes and past climates gave rise to numerous caves, mostly in Palaeozoic carbonate formations.
Jiri Chlachula
wiley   +1 more source

Sex‐specific impact of repeated adolescent vapour exposure to JWH‐018 on dopamine response, behaviour and pharmacokinetics across adolescence and adulthood

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Alarming trends show that vaping e‐cigarettes containing synthetic cannabinoid receptor agonists, such as JWH‐018, is increasing among youth. However, the effects of these trends are unclear in both sexes. We therefore characterized the neuropharmacological effects of adolescent JWH‐018 inhalation in male and female rats.
Nicholas Pintori   +7 more
wiley   +1 more source

Cytochrome P450 1A1 influences obesity‐induced pulmonary hypertension

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose The contribution of obesity to pulmonary arterial hypertension (PAH) pathophysiology remains poorly understood. Adipose tissue synthesises estrogens via cytochrome P450 (CYP) 19A1 (aromatase), whereas circulating estrogens are metabolised in the lung by CYP1A1.
Joshua P. Dignam   +12 more
wiley   +1 more source

Pharmacological inhibition of hydroxysteroid 11‐beta dehydrogenase type 1 (11‐βHSD1) after myocardial infarction preserves cardiac function in a translational mini‐pig model

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Plasma glucocorticoids increase acutely after MI, thereafter tissue levels are amplified selectively within cells expressing 11‐ßhydroxysteroid dehydrogenase type 1 (11‐ßHSD1) that regenerates active glucocorticoids from circulating metabolites.
Sara Al Disi   +19 more
wiley   +1 more source

Search for Dark Matter in 2HDMS at LHC and future Lepton Colliders

open access: green
Dutta, Juhi   +5 more
openalex   +1 more source

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