Universally Coupled Massive Gravity, II: Densitized Tetrad and Cotetrad Theories
Einstein's equations in a tetrad formulation are derived from a linear theory in flat spacetime with an asymmetric potential using free field gauge invariance, local Lorentz invariance and universal coupling.
A. Gruzinov +39 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
On the energy of homogeneous cosmologies
An energy for the homogeneous cosmological models is presented. More specifically, using an appropriate natural prescription, we find the energy within any region with any gravitational source for a large class of gravity theories--namely those with a ...
A. Papapetrou +23 more
core +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
The mediating role of compassion for the others' lives in the relationship between the spouses' dark tetrad personality and verbal violence against women [PDF]
The present study was conducted with the aim of investigating the mediating role of compassion for the others' lives in the relationship between the spouses' dark tetrad personality and verbal violence against women.
Mozaffar Ghaffari, Yousef Hazrati
doaj +1 more source
The Dark Tetrad in the prediction of self-reported and behavioural risk-taking
Objective The explanatory power of the Dark Tetrad of personality (i.e., sub-clinical traits of sadism, psychopathy, narcissism and Machiavellianism) in the prediction of risk-taking behaviours is yet to be determined.
Deborah Nott, Benjamin R. Walker
doaj +1 more source
Modifying the theory of gravity by changing independent variables
We study some particular modifications of gravity in search for a natural way to unify the gravitational and electromagnetic interaction. The certain components of connection in the appearing variants of the theory can be identified with electromagnetic ...
Kharuk, N. V. +3 more
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
O contágio emocional na Dark Tetrad
A Dark Tetrad (DT) tem vindo a ser associada a défices na capacidade empática, sobretudo no que respeita à empatia afetiva. Como parecem ter uma empatia cognitiva preservada, sujeitos com traços DT parecem discernir acerca do estado emocional dos outros mantendo-se frios e distantes desses estados, ou seja, parecem revelar-se menos permeáveis ao ...
openaire +2 more sources
Violation of causality in $f(T)$ gravity
[Abridged] In its standard formulation, the $f(T)$ field equations are not invariant under local Lorentz transformations, and thus the theory does not inherit the causal structure of special relativity.
Otalora, G., Reboucas, M. J.
core +1 more source

