Results 201 to 210 of about 1,358,895 (382)

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

The roles of a light-dependent protochlorophyllide oxidoreductase (LPOR), and ATP-dependent dark operative protochlorophyllide oxidoreductase (DPOR) in chlorophyll biosynthesis

, 2021
Wenli Sun, Mohamad Hesam Shahrajabian, Qi Cheng   +2 more
openalex   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Molecular Mechanisms Preventing Senescence in Response to Prolonged Darkness in a Desiccation-Tolerant Plant1[OPEN]

Plant Physiology, 2018
Meriem R. Durgud, Saurabh Gupta, Ivan Ivanov, M. A. Omidbakhshfard, Maria Benina, S. Alseekh, Nikola Staykov, Mareike Hauenstein, P. Dijkwel, S. Hörtensteiner, V. Toneva, Y. Brotman, A. Fernie, B. Mueller‐Roeber, T. Gechev   +14 more
semanticscholar   +1 more source

Quintessence versus phantom dark energy: the arbitrating power of current and future observations [PDF]

, 2013
B Novosyadlyj, O Sergijenko, R Durrer, V Pelykh   +3 more
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

The Hawking temperature in the context of dark energy for Kerr–Newman and Kerr–Newman–AdS backgrounds [PDF]

, 2019
Goutam Manna, Bivash Majumder
openalex   +1 more source

Empathy as a Mediator of the Effect of Dark Triad Personality, Social Support, and Demographic Factors on Cyberbullying Behavior in SMAN 10 Depok Students [PDF]

, 2022
Bernianti Lingga Sari, Yufi Andriani
openalex   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Wandering in Darkness: Further Reflections [PDF]

, 2012
Eleonore, Stump
core   +1 more source