Results 51 to 60 of about 268,213 (316)

The Darkness of Dark Matter and Dark Energy

open access: yesInternational Journal of Engineering and Applied Sciences (IJEAS), 2018
The visible universemdashincluding Earth, the sun, other stars, and galaxiesmdashis made of protons, neutrons, and electrons bundled together into atoms. Perhaps one of the most surprising discoveries of the 20th century was that this ordinary, or baryonic, matter makes up less than 5 percent of the mass of the universe.
openaire   +2 more sources

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Dark energy and dark gravity: theory overview [PDF]

open access: yesGeneral Relativity and Gravitation, 2007
21 pages 10 figures Overview article for the dark energy issue of GRG revised to match version in print (minor typos corrected 4 refs. added)
Durrer, Ruth, Maartens, Roy
openaire   +7 more sources

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

Dark sector unifications: Dark matter-phantom energy, dark matter - constant w dark energy, dark matter-dark energy-dark matter

open access: yesPhysics Letters B, 2019
The paper brings a novel approach to unification of dark matter and dark energy in terms of a cosmic fluid. A model is introduced in which the cosmic fluid speed of sound squared is defined as a function of its equation of state (EoS) parameter. It is shown how logarithmic part of this function results in dynamical regimes previously not observed in ...
Dalibor Perković, Hrvoje Štefančić
openaire   +4 more sources

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Dipolar dark matter and dark energy [PDF]

open access: yesPhysical Review D, 2009
In previous work [L. Blanchet and A. Le Tiec, Phys. Rev. D 78, 024031 (2008)], a model of dark matter and dark energy based on the concept of gravitational polarization was investigated. This model was shown to recover the concordance cosmological scenario (Lambda-CDM) at cosmological scales, and the phenomenology of the modified Newtonian dynamics ...
Blanchet, Luc, Le Tiec, Alexandre
openaire   +3 more sources

Nightwatch

open access: yesContemporary Aesthetics, 2010
In this essay I examine the features of night, in particular, urban night. I try to highlight the epistemological divide between day and night, light and darkness.
Justin Winkler
doaj  

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

The dark side of cosmology: Dark matter and dark energy [PDF]

open access: yesScience, 2015
A simple model with only six parameters (the age of the universe, the density of atoms, the density of matter, the amplitude of the initial fluctuations, the scale dependence of this amplitude, and the epoch of first star formation) fits all of our cosmological data . Although simple, this standard model is strange.
openaire   +3 more sources

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