Results 181 to 190 of about 146,206 (218)

National Policy on Congenital Heart Disease: Reflections and Proposals for Strengthening Care in Brazil. [PDF]

Arq Bras Cardiol
Miana L, Zheleva B, Passos JPU, Mattos R, Damiano AP, Afiune JY, Horowitz ESK, Jatene MB.   +7 more
europepmc   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

Assessment of Knowledge, Attitude, and Practice (KAP) Among Neuro-Critical Care Nurses in Preventing Ocular Surface Disorders in Unconscious, Mechanically Ventilated Patients. [PDF]

Cureus
Das NK, Das M, C S L.
europepmc   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Clinical and cost-effectiveness of oral versus intramuscular glucocorticoids in rheumatoid arthritis: protocol for a multicentre randomised controlled trial with economic evaluation and qualitative sub-study (LEADER trial). [PDF]

BMJ Open
Cook JA, Wilson N, Wilkins K, Staniland K, Ekang I, Azmi S, Heaney L, Gavan SP, Elliott RA, Wilson RJ, Calvert C, Francis A, Williams JAE, Turner A, Zimmermann A, Richards D, Barton A, Bluett J, LEADER trial network.   +18 more
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Unveiling the Clinical and Biochemical Impact of Vitamin D Deficiency in Indian Rheumatoid Arthritis Patients: A Cross-Sectional Analysis. [PDF]

Cureus
As S, Ca J, Kandi V, Pinnelli VBK, T SB, Sam KT, Gr M, Reddy S, As A.   +8 more
europepmc   +1 more source

Evaluation of Distributed Acoustic Sensing (DAS) Systems with Polarization Diversity for Railway Infrastructure: Effects of Fiber Type and Installation Conditions on System Performance. [PDF]

Sensors (Basel)
Chedid A, Kabalan A, Grand J, Hammi T, Papaiz Garbini G, Gaudot I, Bitri A, Bretaudeau F, Awwad E, Gabet R.   +9 more
europepmc   +1 more source

Epidemiology of glomerular diseases in Northeastern Brazil from 2008-2024. [PDF]

J Bras Nefrol
Sodré AM, Campos MAG, Cutrim ÉMM, Sousa PMB, Oliveira TKM, Teófilo KIM, Guedes FL, Almeida JB, Marques IDB, Alexandre CDS, Vasco RFV, Araújo DV, Ladchumananandasivam FR, Gatto GC, Gomes OV, Costa DMDN, Santana DRM, Muniz MPR, Brito DJA, Salgado Filho N, Neves PDMM, Silva GEB.   +21 more
europepmc   +1 more source