Results 61 to 70 of about 301 (167)

Investigating the Association of Gene Expression of IL-37 Isoforms a and b and Serum IL-37 with Rheumatoid Arthritis Activity and Severity

open access: yesMedical Journal of Babylon
Background: New rheumatoid arthritis (RA) biomarkers, such as serum interleukin-37, may aid in the identification and management as well as improved monitoring of disease severity, activity, and effectiveness of the therapy.
Furqan Hasan Razzaq, Rana Fadhil Obaid
doaj   +1 more source

Efficacy and Baseline Predictors of Tofacitinib Response in Patients with Rheumatoid Arthritis at a Private Tertiary Care Hospital in Pakistan

open access: yesPakistan Armed Forces Medical Journal
Objective: To analyze the efficacy of Tofacitinib and predictors of response in Rheumatoid Arthritis patients Study Design: Prospective longitudinal study Place and Duration of Study: Rheumatology Department, Fauji Foundation Hospital, Rawalpindi ...
Maryam Ahmed   +7 more
doaj   +1 more source

Bioinspired Porphyrin‐Based Catalysts From Temporospatial Confined Frameworks for Ultrafast Removal of Sulfaclozine

open access: yesAdvanced Science, EarlyView.
We report the rational design of artificial photocatalysts with asymmetrically coordinated dual‐metal centers and a tailored microenvironment, broadly applicable strategy is established for the synthesis of multivariate zirconium‐based metal–organic frameworks, offering a platform for precisely tuning active‐site configurations to optimize ...
Yuxin Lu   +11 more
wiley   +1 more source

Comparison of Disease Activity Indices in Patients of Rheumatoid Arthritis

open access: yesJournal of Clinical Rheumatology and Immunology
Objective: To find out correlation between disease activity scores of Rheumatoid arthritis (RA), shedding light on significance of each disease activity score. Patients and methods: It is a cross sectional comparative study.
Maimoona Firdus
doaj   +1 more source

Vitamin D receptor gene polymorphism in rheumatoid arthritis and its association with atherosclerosis

open access: yesEgyptian Rheumatology and Rehabilitation, 2015
Aim of the work Determine vitamin D receptor gene BsmI, FokI polymorphism and 25-hydroxyvitamin D in early Egyptian rheumatoid patients and its association to subclinical atherosclerosis.
Amal M El-Barbary   +4 more
doaj   +1 more source

Ion‐Exchange‐Driven Ternary Organic Neuromorphic Devices with High Efficiency and Stability

open access: yesAdvanced Science, EarlyView.
Spontaneous ion exchange in a ternary polymer–ionic liquid blend disrupts the phase‐separated ionic domains of the binary film and creates a more homogeneous polymer–ion environment. This ionically reorganized matrix enables stable and efficient electrochemical doping, leading to ion‐gel‐gated organic electrochemical transistors with enhanced ...
Sungmin Lee   +14 more
wiley   +1 more source

An Injectable Metal‐Drug Supramolecular Condensate Enables Radiosensitization and Systemic Antitumor Immunity for Post‐Surgical Osteosarcoma Therapy

open access: yesAdvanced Science, EarlyView.
This work designed an injectable metal‐drug supramolecular condensate formed from hafnium ions and alendronate (Hf‐ALN) and loaded with the COX‐2 inhibitor celecoxib (CXB) for synergistic radioimmunotherapy of postoperative osteosarcoma. Mechanistically, upon X‐ray irradiation, Hf enhances radiation energy deposition, ROS generation, and DNA damage ...
Tianhua Xiao   +12 more
wiley   +1 more source

Mitochondria‐Targeted Multimodal Nanotherapeutics Suppress Oxidized mtDNA‐Driven Inflammation at the Source

open access: yesAdvanced Science, EarlyView.
Ox‐mtDNA fragments escaping from mitochondria drive robust inflammatory responses. A targeted nanoplatform simultaneously inhibits mitochondrial FEN1‐mediated mtDNA cleavage and scavenges ROS, preventing the generation of immunogenic Ox‐mtDNA fragments. The released SeNPs further promote autophagic clearance of cytosolic mtDNA. Consequently, cGAS‐STING,
Wen‐Ling Li   +7 more
wiley   +1 more source

Evaluation of Tp-e interval and Tp-e/QT ratio in patients with rheumatoid arthritis

open access: yesTürk Kardiyoloji Derneği Arşivi, 2014
Objective: Several studies have suggested that the interval from the peak to the end of the electrocardiographic T wave (Tp-e) may correspond to the transmural dispersion of repolarization and that inreased Tp-e interval and Tp-e/QT ratio are associated
Gurkan Acar   +9 more
doaj   +1 more source

Ultrasound‐Activated Nanoinhibitors Blocking the Chemo‐Immune Checkpoint to Overcome Chemotherapy‐Induced Immune Resistance

open access: yesAdvanced Science, EarlyView.
A sono‐responsive chemo‐immune checkpoint nanoinhibitor (Sono‐TT8) co‐delivering TPZ chemotherapy and siXkr8 simultaneously kills tumor cells and blocks PS externalization, reversing chemotherapy‐induced immunosuppression and enhancing antitumor immunity. ABSTRACT Breast cancer features an immunosuppressive tumor microenvironment following chemotherapy
Yunfan Liu   +13 more
wiley   +1 more source

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