Results 161 to 170 of about 9,813,695 (247)

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Hänsel und Gretel. Vocal score

, 2012
vocal score (150 p.) 28 ...
Wette, Adelheid (1858 - 1916), Humperdinck, Engelbert (1854 - 1921)   +1 more
core  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Cantemire. Vocal score

With: Charles de France. Selections. Vocal score / musique de Boieldieu ; [parole de MM. Théaulon et Dartois] ; arrangée pour le piano avec accompagnement de violon et basse.
Pierre Gaveaux 1760-1825.
core  

Cherevichki. Vocal score. German & Russian

, 2012
vocal score (299 p.) ; 28 ...
Gogolʹ, Nikolaĭ Vasilʹevich (1809 - 1852), Polonskiĭ, I︠A︡. P. (I︠A︡kov Petrovich) (1819 - 1898), Tchaikovsky, Peter Ilich (1840 - 1893)   +2 more
core  

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Lasset uns ablegen. Vocal score

, 2012
vocal score (23 p.) 28 ...
Bach, Wilhelm Friedemann (1710 - 1784), Weston, George Benson   +1 more
core  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Kupet︠s︡ Kalashnikov. Vocal score. German

, 2012
1 vocal score (273 p.) ; 28 ...
Kulikov, N. I. (Nikolaĭ Ivanovich) (1815 - 1891), Lermontov, Mikhail I︠U︡rʹevich (1814 - 1841), Rubinstein, Anton (1829 - 1894)   +2 more
core  

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source