Results 221 to 230 of about 6,210,082 (250)

Sustained Delivery of a Shingles Subunit Vaccine Overcomes Age‐Related Declines in Humoral and Cellular Immunity Relative to Shingrix

Advanced Science, EarlyView.
Sustained delivery of a shingles subunit vaccine from an injectable polymer–nanoparticle hydrogel enhanced the potency, durability, and breadth of immune responses in aged mice while minimizing inflammatory cytokine production and reactogenicity. This strategy decouples immunogenicity from reactogenicity and offers a promising approach to improve ...
Ye Eun Song, Jerry Yan, Ben S. Ou, Olivia M. Saouaf, Noah Eckman, E. A. Appel   +5 more
wiley   +1 more source

MRI Brain Findings and Clinical Spectrum of Children With Typhus-Positive Acute Encephalitis Syndrome: Associations With Neurological Sequelae. [PDF]

Cureus
Mehta A, Gani S, Shankar V, Kumar A, Ahmad K.   +4 more
europepmc   +1 more source

Cobalt Single‐Atom Nanozyme for Enhanced Intestinal Radioprotection and Tumor Radiosensitization via Bidirectional ROS Modulation

Advanced Science, EarlyView.
Orally administered, pH‐responsive Co‐SAN exerts dual functions: in the alkaline intestinal milieu, it scavenges reactive oxygen species (ROS) and suppresses the PI3K/AKT pathway and NETs formation, thus providing radioprotection; whereas in the acidic tumor microenvironment, it generates ROS and alleviates hypoxia, thereby enhancing radiosensitization.
Shengqi Yin, Junjie Li, Yishu Zou, Yang Liu, Yilin Zheng, Lu Yu, Wanying Zheng, Yajun Zou, Zehui Zhang, Tao Li, Peiqun Yin, Jianlin Zhang, Yuen Wu, Yi Ding   +13 more
wiley   +1 more source

PIF4 enhances temperature-independent tolerance to TSWV in Nicotiana benthamiana. [PDF]

Sci Rep
Sunita G, Lee SY, Venkatesh J, Kwon JK, Kang BC.   +4 more
europepmc   +1 more source

Unraveling Bone‐Skin Crosstalk Enables miRNA Nanoformulation for Cutaneous Neurovascular Reconstruction in Diabetic Mice

Advanced Science, EarlyView.
This study unravels that bone fracture accelerates diabetic wound healing by releasing exosomal microRNA (miR‐130b‐3p). To mimic this bone‐skin crosstalk, we engineered a self‐assembling agomir‐130b‐3p nanocomplex. Delivered via a photocrosslinkable hydrogel, this bio‐inspired therapy provides sustained localized agomir release.
Tao Shen, Hongdou Shen, Weiyue Wu, Zhuoying Jiang, Bin Liu, Yansi Xian, Rui Peng, An Yan, Yu Ben, Yong Shi, Xiang Chen, Baosheng Guo, Qing Jiang, Weijun Wang, Pingqiang Cai   +14 more
wiley   +1 more source

Lupus Retinopathy Mimicking Ocular Tuberculosis: A Diagnostic Dilemma. [PDF]

Cureus
Rawat S, Malhotra S, Lakhlan P, Das S, Bhatt V, Luthra G, Gururani S, Bakaya V, Luthra S.   +8 more
europepmc   +1 more source

Redox and physiological responses of wheat to wheat streak mosaic virus under liposomal bionanocomposite seed treatment. [PDF]

Appl Microbiol Biotechnol
Nyzhnyk T, Kovalenko O, Snihur H, Kiriziy D, Kyrychenko A.   +4 more
europepmc   +1 more source

A Subcellular Keap1-Nrf2 Disruption Strategy for Atopic Dermatitis Therapy. [PDF]

J Med Chem
Zhang Z, Wu J, Liu J, Chan DS, Wong CY, Wang J, Leung CH, Wang W.   +7 more
europepmc   +1 more source

Virus-like particle (VLP)-based indirect ELISA (iELISA) for the detection of beak and feather disease virus (BFDV) antibodies. [PDF]

Appl Microbiol Biotechnol
Dhar PK, Das T, Nath BK, Chowdhury P, Peters A, Forwood JK, Raidal SR, Das S.   +7 more
europepmc   +1 more source

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