Results 191 to 200 of about 19,199 (220)

AB0325 Comparison of Activity Score DAS28-ESR and DAS28 -CRP in Patients with Rheumatoid Arthritis

Annals of the Rheumatic Diseases, 2014
Objectives To compare the disease activity score (DAS)28- ESR versus DAS28 -CRP, and to determine the factors that might influence their difference. Methods Patients with RA were included in a cross-sectional study. We have collected the demographic characteristics and the characteristics of the RA: duration of evolution, morning stiffness in ...
I. Ben Slama, F. Allali, S. El Kabbaj, T. Lakhdar, L. Medrare, A. Ngeuleu, H. Rkain, N. Hajjaj-Hassouni   +7 more
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THU0073 DAS28-CRP and DAS28-ESR Cutoffs for High Disease Activity in Rheumatoid Arthritis Are Not Interchangeable

Annals of the Rheumatic Diseases, 2016
Background Rheumatoid arthritis (RA) clinical trials have shown that mean DAS28 calculated using C-reactive protein (CRP) is lower than DAS28 calculated using erythrocyte sedimentation rate (ESR). We demonstrated that DAS28-CRP cutoffs equivalent to DAS28-ESR for remission and low disease activity (LDA) were 2.4 and 2.9, respectively, rather than 2.6 ...
R.M. Fleischmann, D. van der Heijde, P.V. Gardiner, A. Szumski, L. Marshall, E. Bananis   +5 more
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Is DAS28-CRP with three and four variables interchangeable in individual patients selected for biological treatment in daily clinical practice?

Clinical Rheumatology, 2011
DAS28 is a widely used composite score for the assessment of disease activity in patients with rheumatoid arthritis (RA) and is often used as a treatment decision tool in the daily clinic. Different versions of DAS28 are available.
Ole Rintek Madsen
exaly   +2 more sources

OP0174 The Development of The Modified DAS28-CRP To Improve Agreement with DAS28-ESR and Ensure Appropriate Disease Activity Stratification in RA

Annals of the Rheumatic Diseases, 2016
Background Disease activity in rheumatoid arthritis (RA) has traditionally been measured using the 28-joint count disease activity score (DAS28) using ESR. Use of DAS28 with CRP in place of ESR is increasing. Evidence suggests these scores are not truly interchangeable and agreement varies dependant on disease activity. This study uses the BSRBR-RA to
P.D.H. Hamann, K. Hyrich, A. Jobling, N. McHugh, G. Shaddick, J. Pauling   +5 more
openaire   +1 more source

Construct and criterion validity of several proposed DAS28-based rheumatoid arthritis flare criteria: an OMERACT cohort validation study

Annals of the Rheumatic Diseases, 2013
Item does not contain fulltextBACKGROUND: To describe rheumatoid arthritis (RA) worsening that leads to change or re-initiation of treatment, several Disease Activity Score 28 (DAS28)-based flare criteria have been described, but none validated. METHODS:
Aatke van der Maas, Robin Christensen
exaly   +2 more sources

THU0235 Global Tenderness and Anxiety/Depression as a Component of the DAS28

Annals of the Rheumatic Diseases, 2014
Background The DAS28 (disease activity score 28) was created for the purpose of quantifying and comparing inflammatory processes for patients with Rheumatoid Arthritis. One of the four components measured is a 28 joint tender count. The objectivity of this marker is unclear.
A. Pervez, S. Kelly, B. Kidd
openaire   +1 more source

Remission in rheumatoid arthritis: missing objectives by using inadequate DAS28 targets

Nature Reviews Rheumatology, 2019
For too long, the definition of ‘remission’ in rheumatoid arthritis has been distorted by the widespread use of an inadequate tool, with consequences for clinical care and for making sense of clinical trial data. Has the time come to move away from DAS28-defined remission?
Daniel Aletaha, Josef S. Smolen
openaire   +2 more sources

FRI0573 Integration of Time-Averaged DAS28 Fits Better Joint Destruction In Rheumatoid Arthritis Than One-Time DAS28 and Identifies A Significant Joint-Destructive Association of HLA-DRB1*04:05 Which is Independent of ACPA and DAS28

Annals of the Rheumatic Diseases, 2016
Background Disease Activity Score 28 (DAS28) is one of correlates of joint destruction in rheumatoid arthritis (RA) as well as genetic components, RA-related autoantibodies, and disease duration. Joint destruction is considered to reflect the cumulative history of the disease activities, but one-time DAS28 is used in many studies.
H. Tsuji, C. Terao, K. Yano, K. Ikari, M. Hashimoto, M. Furu, H. Ito, T. Fujii, W. Yamamoto, N. Yamakawa, K. Ohmura, A. Taniguchi, S. Momohara, H. Yamanaka, F. Matsuda, T. Mimori   +15 more
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AB0539 Comparison of RA patients in tocilizumab (TCZ) therapy who showed only DAS28(ESR) remission and both DAS28-ESR and SDAI remission

Annals of the Rheumatic Diseases, 2012
Background The TCZ treatment for RA is known that there is a discrepancy within DAS remission and SDAI remission rate cause by the weight of gravity of acute phase reactants. Especially TCZ strongly inhibits CRP which produced by the liver through the IL-6. Therefore even if we meet to the DAS remission; we come across the cases occasionally who have
I. Yokoe, H. Kobayashi, H. Sato, A. Nishiwaki   +3 more
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FRI0024 Contribution of the Individual Components of the Disease Activity Score (DAS28) to the Total DAS28 Score among Responders and Non-Responders to Biological Therapy for Rheumatoid Arthritis

Annals of the Rheumatic Diseases, 2014
Background The commonly used Disease Activity Score based on 28 joints (DAS28) is a composite index composed of two somewhat subjective components (tender joint count and visual analogue scale general well-being) and two more objective components (swollen joint count and erythrocyte sedimentation rate).
M.S. Jurgens, C.L. Overman, J.W. Jacobs, R. Geenen, B.V. Cuppen, A.C. Marijnissen, J.W. Bijlsma, P.M. Welsing, F.P. Lafeber, J.M. van Laar   +9 more
openaire   +1 more source