Early removal of senescent cells protects retinal ganglion cells loss in experimental ocular hypertension. [PDF]
, 2020 Experimental ocular hypertension induces senescence of retinal ganglion cells (RGCs) that mimics events occurring in human glaucoma. Senescence-related chromatin remodeling leads to profound transcriptional changes including the upregulation of a subset ...
Jabari, Mary +7 more
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Hypopigmentation of the Skin and Hair Associated with Dasatinib Therapy
, 2023 Vishnu Sharma, Vansh Bagrodia
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Combination of subtherapeutic anti-TNF dose with dasatinib restores clinical and molecular arthritogenic profiles better than standard anti-TNF treatment [PDF]
, 2021 Lydia Ntari +10 more
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Therapeutic targeting of chromatin alterations in leukemia and solid tumors
International Journal of Cancer, Volume 158, Issue 2, Page 382-408, 15 January 2026.Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner +7 more
wiley +1 more source
Journal of Electrochemical Science and EngineeringThe main goal of this effort is to create an innovative electrochemical sensor for dasatinib detection in the presence of doxorubicin. It was possible to create Bi2WO6 nanosheets easily.
Mayada Hadi Al-qassi +2 more
doaj +1 more source
Dasatinib + Gefitinib, a non platinum-based combination with enhanced growth inhibitory, anti-migratory and anti-invasive potency against human ovarian cancer cells [PDF]
, 2017 Benoît Thibault, Bertrand Jean-Claude
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Multi‐Omics Integration for Advancing Glioma Precision Medicine
Annals of Clinical and Translational Neurology, Volume 13, Issue 1, Page 4-13, January 2026.ABSTRACT Gliomas are among the most malignant and aggressive tumors of the central nervous system, characterized by the absence of early diagnostic markers, poor prognosis, and a lack of effective treatments. Advances in high‐throughput technologies have facilitated a refined molecular classification of gliomas, incorporating genetic features. However,
Maria Guarnaccia +4 more
wiley +1 more source
Engineering Aging: Approaches to Model and Deconstruct Biological Complexity
Advanced Materials, Volume 38, Issue 1, 2 January 2026.The macro‐experiences of aging are the result of an accumulation of micro‐changes that occur over time. Abstract The disparity between the global increase in life expectancy and the steady decline in health outcomes with age has been a major driver for developing new ways to research aging.
Habib Joukhdar +7 more
wiley +1 more source
Enhancing the Dissolution of Oral Dasatinib Tablets Using Zein–Hydroxypropyl Methylcellulose Solid Dispersions [PDF]
, 2023 Hanan M. Alharbi +7 more
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Mechanical Cues Regulate Cargo Sorting and Export at the Golgi
Advanced Science, Volume 13, Issue 1, 5 January 2026.A pathway is identified linking extracellular matrix stiffness to secretion via Src–FAK–AMPK–GBF1 signaling. Golgi‐localized GBF1 acts as a mechanotransducer whose phosphorylation controls post‐Golgi cargo sorting toward secretion or lysosomal degradation.
Greta Serafino +21 more
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